The kinetic stability of MHC class II: peptide complexes is a key parameter that dictates immunodominance CA Lazarski, FA Chaves, SA Jenks, S Wu, KA Richards, JM Weaver, ... Immunity 23 (1), 29-40, 2005 | 268 | 2005 |
A reappraisal of CTLA-4 checkpoint blockade in cancer immunotherapy X Du, F Tang, M Liu, J Su, Y Zhang, W Wu, M Devenport, CA Lazarski, ... Cell research 28 (4), 416-432, 2018 | 230 | 2018 |
The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II: peptide complexes AJ Sant, FA Chaves, SA Jenks, KA Richards, P Menges, JM Weaver, ... Immunological reviews 207 (1), 261-278, 2005 | 145 | 2005 |
SARS-CoV-2–specific T cells are rapidly expanded for therapeutic use and target conserved regions of the membrane protein MD Keller, KM Harris, MA Jensen-Wachspress, VV Kankate, H Lang, ... Blood, The Journal of the American Society of Hematology 136 (25), 2905-2917, 2020 | 123 | 2020 |
Fibroadipogenic progenitors are responsible for muscle loss in limb girdle muscular dystrophy 2B MW Hogarth, A Defour, C Lazarski, E Gallardo, J Diaz Manera, ... Nature communications 10 (1), 2430, 2019 | 121 | 2019 |
High-intensity focused ultrasound (HIFU) triggers immune sensitization of refractory murine neuroblastoma to checkpoint inhibitor therapy A Eranki, P Srinivasan, M Ries, AR Kim, CA Lazarski, CT Rossi, ... Clinical Cancer Research 26 (5), 1152-1161, 2020 | 118 | 2020 |
IL-4 attenuates Th1-associated chemokine expression and Th1 trafficking to inflamed tissues and limits pathogen clearance CA Lazarski, J Ford, SD Katzman, AF Rosenberg, DJ Fowell PloS one 8 (8), e71949, 2013 | 95 | 2013 |
The impact of DM on MHC class II–restricted antigen presentation can be altered by manipulation of MHC–peptide kinetic stability CA Lazarski, FA Chaves, AJ Sant The Journal of experimental medicine 203 (5), 1319-1328, 2006 | 92 | 2006 |
Direct ex vivo analyses of HLA-DR1 transgenic mice reveal an exceptionally broad pattern of immunodominance in the primary HLA-DR1-restricted CD4 T-cell response to influenza … KA Richards, FA Chaves, FR Krafcik, DJ Topham, CA Lazarski, AJ Sant Journal of virology 81 (14), 7608-7619, 2007 | 83 | 2007 |
Enhanced growth of primary tumors in cancer-prone mice after immunization against the mutant region of an inherited oncoprotein CT Siegel, K Schreiber, SC Meredith, GB Beck-Engeser, DW Lancki, ... The Journal of experimental medicine 191 (11), 1945-1956, 2000 | 75 | 2000 |
Immunodominance in CD4 T-cell responses: implications for immune responses to influenza virus and for vaccine design AJ Sant, FA Chaves, FR Krafcik, CA Lazarski, P Menges, K Richards, ... Expert review of vaccines 6 (3), 357-368, 2007 | 72 | 2007 |
Leishmania induces survival, proliferation and elevated cellular dNTP levels in human monocytes promoting acceleration of HIV co-infection DJ Mock, JA Hollenbaugh, W Daddacha, MG Overstreet, CA Lazarski, ... PLoS pathogens 8 (4), e1002635, 2012 | 60 | 2012 |
Immunodominance of CD4 T cells to foreign antigens is peptide intrinsic and independent of molecular context: implications for vaccine design JM Weaver, CA Lazarski, KA Richards, FA Chaves, SA Jenks, PR Menges, ... The Journal of Immunology 181 (5), 3039-3048, 2008 | 55 | 2008 |
Robust antibody and T cell responses to SARS-CoV-2 in patients with antibody deficiency H Kinoshita, J Durkee-Shock, M Jensen-Wachspress, VV Kankate, ... Journal of Clinical Immunology 41 (6), 1146-1153, 2021 | 51 | 2021 |
MYC drives group 3 medulloblastoma through transformation of Sox2+ astrocyte progenitor cells R Tao, N Murad, Z Xu, P Zhang, K Okonechnikov, M Kool, ... Cancer research 79 (8), 1967-1980, 2019 | 43 | 2019 |
MYC oncogene is associated with suppression of tumor immunity and targeting Myc induces tumor cell immunogenicity for therapeutic whole cell vaccination X Wu, M Nelson, M Basu, P Srinivasan, C Lazarski, P Zhang, P Zheng, ... Journal for immunotherapy of cancer 9 (3), 2021 | 37 | 2021 |
T‐cell receptor sequencing demonstrates persistence of virus‐specific T cells after antiviral immunotherapy MD Keller, S Darko, H Lang, A Ransier, CA Lazarski, Y Wang, PJ Hanley, ... British journal of haematology 187 (2), 206-218, 2019 | 33 | 2019 |
Critical requirement for the Wiskott-Aldrich syndrome protein in Th2 effector function V Morales-Tirado, DK Sojka, SD Katzman, CA Lazarski, FD Finkelman, ... Blood, The Journal of the American Society of Hematology 115 (17), 3498-3507, 2010 | 32 | 2010 |
SARS-CoV-2-specific T cell responses are stronger in children with multisystem inflammatory syndrome compared to children with uncomplicated SARS-CoV-2 infection SR Conway, CA Lazarski, NE Field, M Jensen-Wachspress, H Lang, ... Frontiers in immunology 12, 793197, 2022 | 20 | 2022 |
An aptamer-based targeted delivery of miR-26a protects mice against chemotherapy toxicity while suppressing tumor growth T Tanno, P Zhang, CA Lazarski, Y Liu, P Zheng Blood advances 1 (15), 1107-1119, 2017 | 18 | 2017 |