| Small-molecule–induced DNA damage identifies alternative DNA structures in human genes R Rodriguez, KM Miller, JV Forment, CR Bradshaw, M Nikan, S Britton, ... Nature chemical biology 8 (3), 301-310, 2012 | 706 | 2012 |
| Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining KM Miller, JV Tjeertes, J Coates, G Legube, SE Polo, S Britton, ... Nature structural & molecular biology 17 (99), 1144-1151, 2010 | 691 | 2010 |
| Chemical inhibition of NAT10 corrects defects of laminopathic cells D Larrieu, S Britton, M Demir, R Rodriguez, SP Jackson Science 344 (6183), 527-532, 2014 | 314 | 2014 |
| A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair S Britton, J Coates, SP Jackson J Cell Biol 202 (3), 579-595, 2013 | 292 | 2013 |
| TRF2 and Apollo cooperate with topoisomerase 2α to protect human telomeres from replicative damage J Ye, C Lenain, S Bauwens, A Rizzo, A Saint-Léger, A Poulet, ... Cell 142 (2), 230-242, 2010 | 201 | 2010 |
| DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal S Britton, E Dernoncourt, C Delteil, C Froment, O Schiltz, B Salles, P Frit, ... Nucleic acids research, gku601, 2014 | 196 | 2014 |
| Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks P Chanut, S Britton, J Coates, SP Jackson, P Calsou Nature Communications 7, 2016 | 155 | 2016 |
| Dual Processing of R-Loops and Topoisomerase I Induces Transcription-Dependent DNA Double-Strand Breaks A Cristini, G Ricci, S Britton, S Salimbeni, SN Huang, J Marinello, ... Cell reports 28 (12), 3167-3181. e6, 2019 | 136 | 2019 |
| Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites JS Brown, N Lukashchuk, M Sczaniecka-Clift, S Britton, C le Sage, ... Cell reports 11 (5), 704-714, 2015 | 136 | 2015 |
| ATR controls cellular adaptation to hypoxia through positive regulation of hypoxia-inducible factor 1 (HIF-1) expression F Fallone, S Britton, L Nieto, B Salles, C Muller Oncogene 32 (37), 4387-4396, 2013 | 66 | 2013 |
| Transcription-associated topoisomerase 2α activity is a major effector of cytotoxicity induced by G-quadruplex ligands M Bossaert, A Pipier, JF Riou, C Noirot, LT Nguyễn, RF Serre, O Bouchez, ... Elife 10, e65184, 2021 | 51 | 2021 |
| Cell nonhomologous end joining capacity controls SAF-A phosphorylation by DNA-PK in response to DNA double-strand breaks inducers S Britton, C Froment, P Frit, B Monsarrat, B Salles, P Calsou Cell Cycle 8 (22), 3717-3722, 2009 | 48 | 2009 |
| DNA folds threaten genetic stability and can be leveraged for chemotherapy J Zell, FR Sperti, S Britton, D Monchaud RSC Chemical Biology, 2020 | 41 | 2020 |
| ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks S Britton, P Chanut, C Delteil, N Barboule, P Frit, P Calsou Nucleic Acids Research, 2020 | 37 | 2020 |
| DNA junction ligands trigger DNA damage and are synthetic lethal with DNA repair inhibitors in cancer cells K Duskova, P Lejault, É Benchimol, R Guillot, S Britton, A Granzhan, ... Journal of the American Chemical Society, 2019 | 35 | 2019 |
| BRCA1 prevents R-loop-associated centromeric instability C Racca, S Britton, S Hédouin, C Francastel, P Calsou, F Larminat Cell Death & Disease 12 (10), 1-11, 2021 | 31 | 2021 |
| Identification of three-way DNA junction ligands through screening of chemical libraries and validation by complementary in vitro assays K Duskova, J Lamarche, S Amor, C Caron, N Queyriaux, M Gaschard, ... Journal of medicinal chemistry, 2019 | 30 | 2019 |
| A novel cytoprotective function for the DNA repair protein Ku in regulating p53 mRNA translation and function A Lamaa, M Le Bras, N Skuli, S Britton, P Frit, P Calsou, H Prats, ... EMBO reports 17 (4), 508-518, 2016 | 30 | 2016 |
| ARTEMIS nuclease facilitates apoptotic chromatin cleavage S Britton, P Frit, D Biard, B Salles, P Calsou Cancer research 69 (20), 8120-8126, 2009 | 30 | 2009 |
| Phosphorylation of SAF-A/hnRNP-U serine 59 by Polo-like kinase 1 is required for mitosis P Douglas, R Ye, N Morrice, S Britton, L Trinkle-Mulcahy, SP Lees-Miller Molecular and cellular biology 35 (15), 2699-2713, 2015 | 27 | 2015 |
