Sodium Channel Nav1.5 Controls Epithelial-to-Mesenchymal Transition and Invasiveness in Breast Cancer Cells Through its Regulation by the Salt-Inducible … F Gradek, O Lopez-Charcas, S Chadet, L Poisson, L Ouldamer, ... Scientific reports 9 (1), 18652, 2019 | 59 | 2019 |
The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity O Lopez-Charcas, AM Espinosa, A Alfaro, Z Herrera-Carrillo, ... Scientific reports 8 (1), 12995, 2018 | 48 | 2018 |
Discovery and evaluation of nNav1. 5 sodium channel blockers with potent cell invasion inhibitory activity in breast cancer cells S Dutta, OL Charcas, S Tanner, F Gradek, V Driffort, S Roger, K Selander, ... Bioorganic & medicinal chemistry 26 (9), 2428-2436, 2018 | 38 | 2018 |
P2X7 receptor promotes mouse mammary cancer cell invasiveness and tumour progression, and is a target for anticancer treatment L Brisson, S Chadet, O Lopez-Charcas, B Jelassi, D Ternant, ... Cancers 12 (9), 2342, 2020 | 31 | 2020 |
Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers O Lopez-Charcas, P Pukkanasut, SE Velu, WJ Brackenbury, TG Hales, ... IScience 24 (4), 2021 | 29 | 2021 |
P2x4 receptor promotes mammary cancer progression by sustaining autophagy and associated mesenchymal transition S Chadet, J Allard, L Brisson, O Lopez-Charcas, R Lemoine, A Heraud, ... Oncogene 41 (21), 2920-2931, 2022 | 23 | 2022 |
Voltage-Gated Sodium Channel NaV1.5 Controls NHE−1−Dependent Invasive Properties in Colon Cancer Cells O Lopez-Charcas, L Poisson, O Benouna, R Lemoine, S Chadet, ... Cancers 15 (1), 46, 2022 | 15 | 2022 |
Rock inhibition promotes NaV1.5 sodium channel-dependent SW620 colon cancer cell invasiveness L Poisson, O Lopez-Charcas, S Chadet, E Bon, R Lemoine, L Brisson, ... Scientific reports 10 (1), 13350, 2020 | 15 | 2020 |
Block of human CaV3 channels by the diuretic amiloride O Lopez-Charcas, M Rivera, JC Gomora Molecular Pharmacology 82 (4), 658-667, 2012 | 14 | 2012 |
Novel TASK channels inhibitors derived from dihydropyrrolo [2, 1-a] isoquinoline R Noriega-Navarro, O Lopez-Charcas, B Hernández-Enríquez, ... Neuropharmacology 79, 28-36, 2014 | 9 | 2014 |
Leveraging the ATP‐P2X7 receptor signalling axis to alleviate traumatic CNS damage and related complications Y Yin, L Wei, EA Caseley, O Lopez‐Charcas, Y Wei, D Li, SP Muench, ... Medicinal Research Reviews 43 (5), 1346-1373, 2023 | 7 | 2023 |
Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers. iScience O Lopez-Charcas, P Pukkanasut, SE Velu, WJ Brackenbury, TG Hales, ... doi, 2021 | 6 | 2021 |
P2X7 receptor promotes mouse mammary cancer cell invasiveness and tumour progression, and is a target for anticancer treatment. Cancers (Basel) 12 (9) L Brisson, S Chadet, O Lopez-Charcas, B Jelassi, D Ternant, ... | 5 | 2020 |
The voltage-gated sodium channel Beta4 subunit maintains epithelial phenotype in mammary cells A Doray, R Lemoine, M Severin, S Chadet, O Lopez-Charcas, A Héraud, ... Cells 10 (7), 1624, 2021 | 4 | 2021 |
Blockade of CaV3 calcium channels and induction of G0/G1 cell cycle arrest in colon cancer cells by gossypol O Lopez‐Charcas, O Benouna, R Lemoine, MJ Rosendo‐Pineda, ... British Journal of Pharmacology, 2024 | | 2024 |
Recombinant Intrabodies as Molecular Tools and Potential Therapeutics for Amyotrophic Lateral Sclerosis DR de Assis, A Chami, R Hergesheimer, J Halewa, STA Pour, ... | | 2019 |
Block of Recombinant T-Type Calcium Channels by Gossypol, a Potential Contraceptive O Lopez-Charcas, Z Herrera-Carrillo, LE Montiel-Reyes, JC Gomora Biophysical Journal 110 (3), 440a, 2016 | | 2016 |
Amiloride Docking to T-Type Calcium Channels M Rivera, O López-Charcas, JC Gomora Biophysical Journal 100 (3), 568a, 2011 | | 2011 |