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Rakesh Chatrikhi
Rakesh Chatrikhi
Massachusetts General Hospital Cancer Center
在 mgh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
U2AF1 mutations alter sequence specificity of pre-mRNA binding and splicing
T Okeyo-Owuor, BS White, R Chatrikhi, DR Mohan, S Kim, M Griffith, ...
Leukemia 29 (4), 909-917, 2015
1452015
Wild-type U2AF1 antagonizes the splicing program characteristic of U2AF1-mutant tumors and is required for cell survival
DL Fei, H Motowski, R Chatrikhi, S Prasad, J Yu, S Gao, CL Kielkopf, ...
PLoS Genetics 12 (10), e1006384, 2016
1002016
An extended U2AF65–RNA-binding domain recognizes the 3′ splice site signal
AA Agrawal, E Salsi, R Chatrikhi, S Henderson, JL Jenkins, MR Green, ...
Nature communications 7 (1), 10950, 2016
732016
RNA binding protein CELF2 regulates signal-induced alternative polyadenylation by competing with enhancers of the polyadenylation machinery
R Chatrikhi, MJ Mallory, MR Gazzara, LM Agosto, WS Zhu, AJ Litterman, ...
Cell reports 28 (11), 2795-2806. e3, 2019
392019
Alternative splicing redefines landscape of commonly mutated genes in acute myeloid leukemia
OD Rivera, MJ Mallory, M Quesnel-Vallières, R Chatrikhi, DC Schultz, ...
Proceedings of the National Academy of Sciences 118 (15), e2014967118, 2021
352021
A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex
R Chatrikhi, Feeney CF, Pulvino MJ, Alachouzos G, MacRae AJ, Falls Z, Rai S ...
Cell Chemical Biology, 2021
302021
Reciprocal regulation of hnRNP C and CELF2 through translation and transcription tunes splicing activity in T cells
MJ Mallory, SP McClory, R Chatrikhi, MR Gazzara, RJ Ontiveros, ...
Nucleic acids research 48 (10), 5710-5719, 2020
242020
SF1 phosphorylation enhances specific binding to U2AF65 and reduces binding to 3′-splice-site RNA
R Chatrikhi, W Wang, A Gupta, S Loerch, A Maucuer, CL Kielkopf
Biophysical Journal 111 (12), 2570-2586, 2016
182016
A synthetic molecule stalls pre-mRNA splicing by enhancing cancer-relevant U2AF2–RNA complexes
C. L. Kielkopf, C. F. Feeney, R. Chatrikhi, A. MacRae, G. Alachouzos, Z ...
Acta Cryst. 75 (103), 2019
2019
Understanding and Modulating RNA Recognition of Myelodysplasia-Relevant Pre-mRNA Splicing Factor U2AF35
R Chatrikhi
University of Rochester School of Medicine and Dentistry (http://hdl.handle …, 2016
2016
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