HOXBLINC long non-coding RNA activation promotes leukemogenesis in NPM1-mutant acute myeloid leukemia G Zhu, H Luo, Y Feng, OA Guryanova, J Xu, S Chen, Q Lai, A Sharma, ... Nature communications 12 (1), 1956, 2021 | 36 | 2021 |
Alterations to DNMT3A in Hematologic Malignancies K Venugopal, Y Feng, D Shabashvili, OA Guryanova Cancer research 81 (2), 254-263, 2021 | 36 | 2021 |
Inhibition of Polo-like kinase 2 ameliorates pathogenesis in Alzheimer’s disease model mice JS Lee, Y Lee, EA André, KJ Lee, T Nguyen, Y Feng, N Jia, BT Harris, ... PLoS One 14 (7), e0219691, 2019 | 32 | 2019 |
DNMT3A harboring leukemia-associated mutations directs sensitivity to DNA damage at replication forks K Venugopal, Y Feng, P Nowialis, H Xu, DE Shabashvili, CM Berntsen, ... Clinical Cancer Research 28 (4), 756-769, 2022 | 14 | 2022 |
Kappa opioid receptors regulate hippocampal synaptic homeostasis and epileptogenesis BN Queenan, RL Dunn, VR Santos, Y Feng, MN Huizenga, RJ Hammack, ... Epilepsia 59 (1), 106-122, 2018 | 14 | 2018 |
IDH1-Mutant Preleukemic Hematopoietic Stem Cells Can Be Eliminated by Inhibition of Oxidative Phosphorylation N Landberg, T Köhnke, Y Feng, Y Nakauchi, AC Fan, MH Linde, ... Blood cancer discovery 5 (2), 114-131, 2024 | 9 | 2024 |
miR-196b–TLR7/8 Signaling Axis Regulates Innate Immune Signaling and Myeloid Maturation in DNMT3A-Mutant AML HA Gamlen, JS Romer-Seibert, ME Lawler, AM Versace, ML Goetz, ... Clinical Cancer Research 28 (20), 4574-4586, 2022 | 9 | 2022 |
Combination strategies to promote sensitivity to cytarabine-induced replication stress in acute myeloid leukemia with and without DNMT3A mutations DE Shabashvili, Y Feng, P Kaur, K Venugopal, OA Guryanova Experimental hematology 110, 20-27, 2022 | 9 | 2022 |
Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer Y Feng, Q Yuan, RC Newsome, T Robinson, RL Bowman, AN Zuniga, ... Journal of Experimental Medicine 220 (11), e20230011, 2023 | 7 | 2023 |
Dnmt3a mutations in the hematopoietic system promote colitis-associated colon cancer: A model of clonal hematopoiesis in solid tumors Y Feng, R Newsome, T Robinson, RL Bowman, A Zuniga, K Hall, ... Blood 138, 2161, 2021 | 4 | 2021 |
DNMT3A alterations associated with myeloid malignancies dictate differential responses to hypomethylating agents HLC Roman, K Venugopal, Y Feng, DE Shabashvili, LM Posada, J Li, ... Leukemia research 94, 106372, 2020 | 3 | 2020 |
Gene Correction of DNMT3A: R882H in Primary Human AML Demonstrates That This Mutation Is Not Required for Disease Maintenance, but Is Associated with Increased Leukemia Stem … T Koehnke, D Karigane, E Hilgart, K Kayamori, AC Fan, CT Collins, ... Blood 142, 579, 2023 | 1 | 2023 |
DNMT3A with leukemia-associated mutations directs sensitivity to DNA damage at replication forks K Venugopal, DE Shabashvili, J Li, LM Posada, RL Bennett, Y Feng, ... Blood 134, 535, 2019 | 1 | 2019 |
THE EFFECT OF CLONAL HEMATOPOIESIS ON THE MOLECULAR PATHOPHYSIOLOGY OF SOLID TUMORS Y Feng University of Florida, 2024 | | 2024 |
A new era of functional experimentation in human hematopoiesis and leukemia research T Köhnke, Y Feng, R Majeti Experimental Hematology, 104652, 2024 | | 2024 |
DNMT3AR882H Is Not Required for Disease Maintenance in Primary Human AML, but Is Associated With Increased Leukemia Stem Cell Frequency T Koehnke, D Karigane, E Hilgart, AC Fan, K Kayamori, M Miyauchi, ... bioRxiv, 2024.10. 26.620318, 2024 | | 2024 |
DNMT3A with Leukemia-Associated R882 Mutations Promotes Fitness Advantage through Functional Heterogeneity within HSCs Z Zaroogian, C Gunaratne, D Shabashvili, C Berntsen, Y Feng, ... Blood 138, 2151, 2021 | | 2021 |
3015–CLONAL HEMATOPOIESIS DRIVEN BY PARTIAL DNMT3A LOSS CONTRIBUTES TO AN AGGRESSIVE PHENOTYPE OF COLITIS-ASSOCIATED COLON CANCER OA Guryanova, Y Feng, R Newsome, T Robinson, R Bowman, A Zuniga, ... Experimental Hematology 100, S50, 2021 | | 2021 |
NPM1 mutation mediated HOXBLINC lncRNA activation promotes AML leukemogenesis G Zhu, H Luo, Y Feng, O Guryanova, J Xu, S Chen, Q Lai, B Xu, Z Zhao, ... | | 2020 |
3141–LEUKEMIA-ASSOCIATED MUTATIONS IN DNMT3A MEDIATE SENSITIVITY TO REPLICATION STRESS INDUCED BY NUCLEOSIDE ANALOGS K Venugopal, D Shabashvili, J Li, Y Feng, A Riva, S Pondugula, ... Experimental Hematology 88, S82, 2020 | | 2020 |