Nanoparticle biodistribution coefficients: A quantitative approach for understanding the tissue distribution of nanoparticles M Kumar, P Kulkarni, S Liu, N Chemuturi, DK Shah Advanced Drug Delivery Reviews 194, 114708, 2023 | 42 | 2023 |
The universally unrecognized assumption in predicting drug clearance and organ extraction ratio LZ Benet, S Liu, AR Wolfe Clinical Pharmacology & Therapeutics 103 (3), 521-525, 2018 | 37 | 2018 |
Effect of variable domain charge on in vitro and in vivo disposition of monoclonal antibodies S Liu, A Verma, H Kettenberger, WF Richter, DK Shah MAbs 13 (1), 1993769, 2021 | 31 | 2021 |
The extended clearance concept following oral and intravenous dosing: theory and critical analyses LZ Benet, CM Bowman, S Liu, JK Sodhi Pharmaceutical research 35, 1-12, 2018 | 21 | 2018 |
Physiologically Based Pharmacokinetic Modeling to Characterize the Effect of Molecular Charge on Whole-Body Disposition of Monoclonal Antibodies S Liu, DK Shah The AAPS Journal 25 (3), 48, 2023 | 8 | 2023 |
Mathematical Models to Characterize the Absorption, Distribution, Metabolism, and Excretion of Protein Therapeutics S Liu, DK Shah Drug Metabolism and Disposition 50 (6), 867-878, 2022 | 4 | 2022 |
Clinical validation of translational antibody PBPK model using tissue distribution data generated with 89Zr-immuno-PET imaging S Liu, Z Li, M Huisman, DK Shah Journal of Pharmacokinetics and Pharmacodynamics 50 (5), 377-394, 2023 | 3 | 2023 |
Pharmacokinetics of AAV9 Mediated Trastuzumab Expression in Rat Brain Following Systemic and Local Administration EA Chowdhury, M Ahuja, S Wu, S Liu, HW Huang, M Kumar, KS Sunkara, ... Journal of Pharmaceutical Sciences 113 (1), 131-140, 2024 | 2 | 2024 |
Whole-Body Disposition and Physiologically Based Pharmacokinetic Modeling of Adeno-Associated Viruses and the Transgene Product S Liu, EA Chowdhury, V Xu, A Jerez, L Mahmood, BQ Ly, HK Le, ... Journal of Pharmaceutical Sciences 113 (1), 141-157, 2024 | 1 | 2024 |
Translational two-pore PBPK model to characterize whole-body disposition of different-size endogenous and exogenous proteins S Liu, Y Li, Z Li, S Wu, JM Harrold, DK Shah Journal of Pharmacokinetics and Pharmacodynamics, 1-28, 2024 | | 2024 |
Development of a generalized pharmacokinetic model to characterize clinical pharmacokinetics of monomethyl auristatin E‐based antibody–drug conjugates HP Chang, YK Cheung, S Liu, DK Shah British Journal of Clinical Pharmacology, 2024 | | 2024 |
Physiologically based pharmacokinetic modeling of adeno-associated viruses and the transgene product S Liu, E Chowdhury, G Meno-Tetang, D Shah Drug Metabolism and Pharmacokinetics 55, 100974, 2024 | | 2024 |
Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice S Liu, SC Humphreys, KD Cook, KP Conner, AR Correia, AW Jacobitz, ... Mabs 15 (1), 2263926, 2023 | | 2023 |
Special Section on Pharmacokinetics and ADME of Biological Therapeutics-Minireview S Liu, DK Shah DRUG METABOLISM AND DISPOSITION 50 (6), 867-878, 2022 | | 2022 |
Development and Application of a Single Cell-Level PK-PD Model for ADCs S Liu, DK Shah Quantitative Analysis of Cellular Drug Transport, Disposition, and Delivery …, 2021 | | 2021 |