hTERT alone immortalizes epithelial cells of renal proximal tubules without changing their functional characteristics M Wieser, G Stadler, P Jennings, B Streubel, W Pfaller, P Ambros, C Riedl, ... American Journal of Physiology-Renal Physiology 295 (5), F1365-F1375, 2008 | 339 | 2008 |
Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of Toxicology 91, 3477-3505, 2017 | 336 | 2017 |
Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress A Wilmes, A Limonciel, L Aschauer, K Moenks, C Bielow, MO Leonard, ... Journal of proteomics 79, 180-194, 2013 | 194 | 2013 |
Evidence for a role of uromodulin in chronic kidney disease progression S Prajczer, U Heidenreich, W Pfaller, P Kotanko, K Lhotta, P Jennings Nephrology Dialysis Transplantation 25 (6), 1896-1903, 2010 | 180 | 2010 |
In vitro evaluation of the toxicity induced by nickel soluble and particulate forms in human airway epithelial cells E Forti, S Salovaara, Y Cetin, A Bulgheroni, R Tessadri, P Jennings, ... Toxicology in vitro 25 (2), 454-461, 2011 | 174 | 2011 |
An overview of transcriptional regulation in response to toxicological insult P Jennings, A Limonciel, L Felice, MO Leonard Archives of toxicology 87, 49-72, 2013 | 162 | 2013 |
Cyclosporine A induces senescence in renal tubular epithelial cells P Jennings, C Koppelstaetter, S Aydin, T Abberger, AM Wolf, G Mayer, ... American Journal of Physiology-Renal Physiology 293 (3), F831-F838, 2007 | 154 | 2007 |
Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics A Wilmes, C Bielow, C Ranninger, P Bellwon, L Aschauer, A Limonciel, ... Toxicology in Vitro 30 (1), 117-127, 2015 | 139 | 2015 |
A review of the evidence that ochratoxin A is an Nrf2 inhibitor: implications for nephrotoxicity and renal carcinogenicity A Limonciel, P Jennings Toxins 6 (1), 371-379, 2014 | 136 | 2014 |
Advanced good cell culture practice for human primary, stem cell-derived and organoid models as well as microphysiological systems D Pamies, AK Bal-Price, C Chesné, S Coecke, A Dinnyes, C Eskes, ... | 129 | 2018 |
The surface properties of nanocrystalline diamond and nanoparticulate diamond powder and their suitability as cell growth support surfaces T Lechleitner, F Klauser, T Seppi, J Lechner, P Jennings, P Perco, ... Biomaterials 29 (32), 4275-4284, 2008 | 123 | 2008 |
The future of in vitro toxicology P Jennings Toxicology in Vitro 29 (6), 1217-1221, 2015 | 114 | 2015 |
Systems toxicology: real world applications and opportunities T Hartung, RE FitzGerald, P Jennings, GR Mirams, MC Peitsch, ... Chemical research in toxicology 30 (4), 870-882, 2017 | 107 | 2017 |
Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity A Wilmes, D Crean, S Aydin, W Pfaller, P Jennings, MO Leonard Toxicology In Vitro 25 (3), 613-622, 2011 | 102 | 2011 |
Expression of xenobiotic transporters in the human renal proximal tubule cell line RPTEC/TERT1 L Aschauer, G Carta, N Vogelsang, E Schlatter, P Jennings Toxicology in Vitro 30 (1), 95-105, 2015 | 95 | 2015 |
Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes A Limonciel, L Aschauer, A Wilmes, S Prajczer, MO Leonard, W Pfaller, ... Toxicology in Vitro 25 (8), 1855-1862, 2011 | 93 | 2011 |
Delineation of the key aspects in the regulation of epithelial monolayer formation L Aschauer, LN Gruber, W Pfaller, A Limonciel, TJ Athersuch, R Cavill, ... Molecular and cellular biology 33 (13), 2535-2550, 2013 | 90 | 2013 |
Membrane targeting and secretion of mutant uromodulin in familial juvenile hyperuricemic nephropathy P Jennings, S Aydin, P Kotanko, J Lechner, K Lhotta, S Williams, ... Journal of the American Society of Nephrology 18 (1), 264-273, 2007 | 89 | 2007 |
Ca2+ entry is essential for cell strain-induced lamellar body fusion in isolated rat type II pneumocytes M Frick, C Bertocchi, P Jennings, T Haller, N Mair, W Singer, W Pfaller, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 286 (1 …, 2004 | 73 | 2004 |
The carcinoGENOMICS project: critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays M Vinken, T Doktorova, H Ellinger-Ziegelbauer, HJ Ahr, E Lock, ... Mutation Research/Reviews in Mutation Research 659 (3), 202-210, 2008 | 68 | 2008 |