Non-electrophilic TRPA1 agonists, menthol, carvacrol and clotrimazole, open epithelial tight junctions via TRPA1 activation M Mukaiyama, T Usui, Y Nagumo The journal of biochemistry 168 (4), 407-415, 2020 | 19 | 2020 |
Structure optimization of gatastatin for the development of γ-tubulin-specific inhibitor K Shintani, H Ebisu, M Mukaiyama, T Hatanaka, T Chinen, D Takao, ... ACS Medicinal Chemistry Letters 11 (6), 1125-1129, 2020 | 10 | 2020 |
Transient receptor potential V4 channel stimulation induces reversible epithelial cell permeability in MDCK cell monolayers M Mukaiyama, Y Yamasaki, T Usui, Y Nagumo FEBS letters 593 (16), 2250-2260, 2019 | 10 | 2019 |
Structural revision of natural cyclic depsipeptide MA026 established by total synthesis and biosynthetic gene cluster analysis C Uchiyama, A Fukuda, M Mukaiyama, Y Nakazawa, Y Kuramochi, ... Angewandte Chemie International Edition 60 (16), 8792-8797, 2021 | 7 | 2021 |
Capsaicin indirectly regulates TRPA1 via the arachidonic acid cascade, resulting in TJ opening Y Kanda, M Mukaiyama, Y Yamasaki, T Usui, Y Nagumo Bioscience, Biotechnology, and Biochemistry 88 (1), 44-52, 2024 | | 2024 |
X-Ray Conformation and Structure–Activity Relationships of MA026, a Reversible Tight Junction Opener M Mukaiyama, C Uchiyama, A Fukuda, Y Nakazawa, Y Kuramochi, ... Journal of Medicinal Chemistry 66 (13), 8717-8724, 2023 | | 2023 |
Cell layer permeation promoter. composition for facilitating drug absorption. and pharmaceutical composition T Usui, Y Nagumo, M Mukaiyama, Y Hayashi, A Taniguchi, C Uchiyama US Patent App. 17/442,797, 2022 | | 2022 |
非侵襲的薬剤投与法を可能とする上皮タイトジャンクション可逆的開口剤の開発 注射・点滴に依らない医薬品投与を目指して 臼井健郎, 向山海凪, 南雲陽子 化学と生物 58 (4), 204-209, 2020 | | 2020 |