mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern RR Goel, MM Painter, SA Apostolidis, D Mathew, W Meng, AM Rosenfeld, ... Science 374 (6572), abm0829, 2021 | 814 | 2021 |
Single-cell analyses identify brain mural cells expressing CD19 as potential off-tumor targets for CAR-T immunotherapies KR Parker, D Migliorini, E Perkey, KE Yost, A Bhaduri, P Bagga, M Haris, ... Cell 183 (1), 126-142. e17, 2020 | 389 | 2020 |
Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19 LA Vella, JR Giles, AE Baxter, DA Oldridge, C Diorio, L Kuri-Cervantes, ... Science immunology 6 (57), eabf7570, 2021 | 221 | 2021 |
Menin inhibitor MI-3454 induces remission in MLL1-rearranged and NPM1-mutated models of leukemia S Klossowski, H Miao, K Kempinska, T Wu, T Purohit, EG Kim, ... The Journal of clinical investigation 130 (2), 981-997, 2020 | 196 | 2020 |
An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling H Jun, H Yu, J Gong, J Jiang, X Qiao, E Perkey, D Kim, MP Emont, ... Nature medicine 24 (6), 814-822, 2018 | 91 | 2018 |
Fibroblastic niches prime T cell alloimmunity through Delta-like Notch ligands J Chung, CL Ebens, E Perkey, V Radojcic, U Koch, L Scarpellino, A Tong, ... The Journal of clinical investigation 127 (4), 1574-1588, 2017 | 85 | 2017 |
New insights into graft-versus-host disease and graft rejection E Perkey, I Maillard Annual Review of Pathology: Mechanisms of Disease 13 (1), 219-245, 2018 | 67 | 2018 |
Cytomegalovirus latent infection is associated with an increased risk of COVID-19-related hospitalization C Alanio, A Verma, D Mathew, S Gouma, G Liang, T Dunn, DA Oldridge, ... The Journal of Infectious Diseases 226 (3), 463-473, 2022 | 55 | 2022 |
BCL6 antagonizes NOTCH2 to maintain survival of human follicular lymphoma cells E Valls, C Lobry, H Geng, L Wang, M Cardenas, M Rivas, L Cerchietti, ... Cancer discovery 7 (5), 506-521, 2017 | 53 | 2017 |
Signaling through FcγRIIA and the C5a-C5aR pathway mediate platelet hyperactivation in COVID-19 SA Apostolidis, A Sarkar, HM Giannini, RR Goel, D Mathew, A Suzuki, ... Frontiers in immunology 13, 834988, 2022 | 49 | 2022 |
Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice V Radojcic, K Paz, J Chung, J Du, ET Perkey, R Flynn, S Ivcevic, M Zaiken, ... Blood, The Journal of the American Society of Hematology 132 (20), 2188-2200, 2018 | 38 | 2018 |
Acetylcholine‐synthesizing macrophages in subcutaneous fat are regulated by β2‐adrenergic signaling AJ Knights, S Liu, Y Ma, VS Nudell, E Perkey, MJ Sorensen, RT Kennedy, ... The EMBO journal 40 (24), e106061, 2021 | 32 | 2021 |
GCNT1-mediated O-glycosylation of the sialomucin CD43 is a sensitive indicator of notch signaling in activated T cells E Perkey, DM De Sousa, L Carrington, J Chung, A Dils, D Granadier, ... The Journal of Immunology 204 (6), 1674-1688, 2020 | 28 | 2020 |
Increased mammalian target of rapamycin complex 2 signaling promotes age-related decline in CD4 T cell signaling and function E Perkey, D Fingar, RA Miller, GG Garcia The Journal of Immunology 191 (9), 4648-4655, 2013 | 23 | 2013 |
Early notch signals induce a pathogenic molecular signature during priming of alloantigen-specific conventional CD4+ T cells in graft-versus-host disease J Chung, V Radojcic, E Perkey, TJ Parnell, Y Niknafs, X Jin, A Friedman, ... The Journal of Immunology 203 (2), 557-568, 2019 | 14 | 2019 |
Ex vivo enzymatic treatment of aged CD4 T cells restores cognate T cell helper function and enhances antibody production in mice E Perkey, RA Miller, GG Garcia The Journal of Immunology 189 (12), 5582-5589, 2012 | 14 | 2012 |
TPP1 mutagenesis screens unravel shelterin interfaces and functions in hematopoiesis S Grill, S Padmanaban, A Friedman, E Perkey, F Allen, VM Tesmer, ... JCI insight 6 (9), 2021 | 12 | 2021 |
DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance N Zhou, J Choi, G Grothusen, BJ Kim, D Ren, Z Cao, Y Liu, Q Li, ... Blood 142 (11), 973-988, 2023 | 9 | 2023 |
Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells DG Atria, BT Gaudette, J Londregan, S Kelly, E Perkey, A Allman, ... The Journal of Clinical Investigation 132 (13), 2022 | 9 | 2022 |
Notch signaling drives intestinal graft-versus-host disease in mice and nonhuman primates V Tkachev, A Vanderbeck, E Perkey, SN Furlan, C McGuckin, ... Science Translational Medicine 15 (702), eadd1175, 2023 | 7 | 2023 |