n→ π* interactions in proteins GJ Bartlett, A Choudhary, RT Raines, DN Woolfson Nature chemical biology 6 (8), 615-620, 2010 | 367 | 2010 |
Targeting the pancreatic β-cell to treat diabetes A Vetere, A Choudhary, S Burns, B Wagner Nature Reviews Drug Discovery, 2014 | 330 | 2014 |
Nature of amide carbonyl− carbonyl interactions in proteins A Choudhary, D Gandla, GR Krow, RT Raines Journal of the American Chemical Society 131 (21), 7244-7246, 2009 | 274 | 2009 |
An evaluation of peptide‐bond isosteres A Choudhary, RT Raines ChemBioChem 12 (12), 1801-1807, 2011 | 255 | 2011 |
Multidimensional chemical control of CRISPR–Cas9 B Maji, CL Moore, B Zetsche, SE Volz, F Zhang, MD Shoulders, ... Nature chemical biology 13 (1), 9-11, 2017 | 180 | 2017 |
A high-throughput platform to identify small-molecule inhibitors of CRISPR-Cas9 B Maji, SA Gangopadhyay, M Lee, M Shi, P Wu, R Heler, B Mok, D Lim, ... Cell 177 (4), 1067-1079. e19, 2019 | 169 | 2019 |
n → π* Interaction and n)(π Pauli Repulsion Are Antagonistic for Protein Stability CE Jakobsche, A Choudhary, SJ Miller, RT Raines Journal of the American Chemical Society 132 (19), 6651-6653, 2010 | 134 | 2010 |
Precision control of CRISPR-Cas9 using small molecules and light SA Gangopadhyay, KJ Cox, D Manna, D Lim, B Maji, Q Zhou, ... Biochemistry 58 (4), 234-244, 2019 | 116 | 2019 |
Phosphorylation-inducing chimeric small molecules SU Siriwardena, DNP Munkanatta Godage, VM Shoba, S Lai, M Shi, ... Journal of the American Chemical Society 142 (33), 14052-14057, 2020 | 107 | 2020 |
Intimate Interactions with Carbonyl Groups: Dipole–Dipole or n→π*? KJ Kamer, A Choudhary, RT Raines The Journal of organic chemistry 78 (5), 2099-2103, 2013 | 99 | 2013 |
Core commitments for field trials of gene drive organisms KC Long, L Alphey, GJ Annas, CS Bloss, KJ Campbell, J Champer, ... Science 370 (6523), 1417-1419, 2020 | 78 | 2020 |
The Aberrance of the 4S Diastereomer of 4-Hydroxyproline MD Shoulders, FW Kotch, A Choudhary, IA Guzei, RT Raines Journal of the American Chemical Society 132 (31), 10857-10865, 2010 | 75 | 2010 |
An n→π* Interaction in Aspirin: Implications for Structure and Reactivity A Choudhary, KJ Kamer, RT Raines The Journal of organic chemistry 76 (19), 7933-7937, 2011 | 71 | 2011 |
Signature of n→ π* interactions in α‐helices A Choudhary, RT Raines Protein Science 20 (6), 1077-1081, 2011 | 62 | 2011 |
A stereoelectronic effect in prebiotic nucleotide synthesis A Choudhary, KJ Kamer, MW Powner, JD Sutherland, RT Raines ACS chemical biology 5 (7), 655-657, 2010 | 56 | 2010 |
Small-molecule control of super-Mendelian inheritance in gene drives VL Del Amo, BS Leger, KJ Cox, S Gill, AL Bishop, GD Scanlon, JA Walker, ... Cell reports 31 (13), 2020 | 49 | 2020 |
n→π* Interactions Engender Chirality in Carbonyl Groups A Choudhary, RW Newberry, RT Raines Organic letters 16 (13), 3421-3423, 2014 | 49 | 2014 |
A Singular System with Precise Dosing and Spatiotemporal Control of CRISPR‐Cas9 D Manna, B Maji, SA Gangopadhyay, KJ Cox, Q Zhou, BK Law, ... Angewandte Chemie 131 (19), 6351-6355, 2019 | 46 | 2019 |
CRISPR-based therapeutics: current challenges and future applications AE Modell, D Lim, TM Nguyen, V Sreekanth, A Choudhary Trends in pharmacological sciences 43 (2), 151-161, 2022 | 44 | 2022 |
Engineering designer beta cells with a CRISPR-Cas9 conjugation platform D Lim, V Sreekanth, KJ Cox, BK Law, BK Wagner, JM Karp, A Choudhary Nature communications 11 (1), 4043, 2020 | 41 | 2020 |