| USP7 small-molecule inhibitors interfere with ubiquitin binding L Kategaya, P Di Lello, L Rougé, R Pastor, KR Clark, J Drummond, ... Nature 550 (7677), 534-538, 2017 | 290 | 2017 |
| Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization B Graves, T Thompson, M Xia, C Janson, C Lukacs, D Deo, P Di Lello, ... Proceedings of the National Academy of Sciences 109 (29), 11788-11793, 2012 | 254 | 2012 |
| Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53 P Di Lello, LMM Jenkins, TN Jones, BD Nguyen, T Hara, H Yamaguchi, ... Molecular cell 22 (6), 731-740, 2006 | 241 | 2006 |
| Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor Y Zhang, C Eigenbrot, L Zhou, S Shia, W Li, C Quan, J Tom, P Moran, ... Journal of Biological Chemistry 289 (2), 942-955, 2014 | 167 | 2014 |
| Molecular understanding of USP7 substrate recognition and C-terminal activation L Rougé, TW Bainbridge, M Kwok, R Tong, P Di Lello, IE Wertz, T Maurer, ... Structure 24 (8), 1335-1345, 2016 | 95 | 2016 |
| A stable mercury-containing complex of the organomercurial lyase MerB: catalysis, product release, and direct transfer to MerA GC Benison, P Di Lello, JE Shokes, NJ Cosper, RA Scott, P Legault, ... Biochemistry 43 (26), 8333-8345, 2004 | 82 | 2004 |
| Crystal structures of the organomercurial lyase MerB in its free and mercury-bound forms: insights into the mechanism of methylmercury degradation J Lafrance-Vanasse, M Lefebvre, P Di Lello, J Sygusch, JG Omichinski Journal of Biological Chemistry 284 (2), 938-944, 2009 | 77 | 2009 |
| Discovery of small-molecule inhibitors of ubiquitin specific protease 7 (USP7) using integrated NMR and in silico techniques P Di Lello, R Pastor, JM Murray, RA Blake, F Cohen, TD Crawford, ... Journal of medicinal chemistry 60 (24), 10056-10070, 2017 | 72 | 2017 |
| NMR structure of the complex between the Tfb1 subunit of TFIIH and the activation domain of VP16: structural similarities between VP16 and p53 C Langlois, C Mas, P Di Lello, LMM Jenkins, P Legault, JG Omichinski Journal of the American Chemical Society 130 (32), 10596-10604, 2008 | 72 | 2008 |
| Structural and functional characterization of an atypical activation domain in erythroid Krüppel-like factor (EKLF) C Mas, M Lussier-Price, S Soni, T Morse, G Arseneault, P Di Lello, ... Proceedings of the National Academy of Sciences 108 (26), 10484-10489, 2011 | 65 | 2011 |
| GATA-1 associates with and inhibits p53 CD Trainor, C Mas, P Archambault, P Di Lello, JG Omichinski Blood, The Journal of the American Society of Hematology 114 (1), 165-173, 2009 | 65 | 2009 |
| Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists Y Zhang, M Ultsch, NJ Skelton, DJ Burdick, MH Beresini, W Li, ... Nature structural & molecular biology 24 (10), 848-856, 2017 | 59 | 2017 |
| NMR Structure of the Amino-Terminal Domain from the Tfb1 Subunit of TFIIH and Characterization of Its Phosphoinositide and VP16 Binding Sites, P Di Lello, BD Nguyen, TN Jones, K Potempa, MS Kobor, P Legault, ... Biochemistry 44 (21), 7678-7686, 2005 | 56 | 2005 |
| NMR Structure of the Single QALGGH Zinc Finger Domain from the Arabidopsis thaliana SUPERMAN Protein C Isernia, E Bucci, M Leone, L Zaccaro, P Di Lello, G Digilio, S Esposito, ... Chembiochem 4 (2‐3), 171-180, 2003 | 56 | 2003 |
| p53 and TFIIEα share a common binding site on the Tfb1/p62 subunit of TFIIH P Di Lello, LM Miller Jenkins, C Mas, C Langlois, E Malitskaya, ... Proceedings of the National Academy of Sciences 105 (1), 106-111, 2008 | 54 | 2008 |
| NMR Structural Studies Reveal a Novel Protein Fold for MerB, the Organomercurial Lyase Involved in the Bacterial Mercury Resistance System, P Di Lello, GC Benison, H Valafar, KE Pitts, AO Summers, P Legault, ... Biochemistry 43 (26), 8322-8332, 2004 | 50 | 2004 |
| Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease JD Dikeakos, P Di Lello, MJ Lacombe, R Ghirlando, P Legault, ... Proceedings of the National Academy of Sciences 106 (18), 7408-7413, 2009 | 49 | 2009 |
| An allosteric pan-TEAD inhibitor blocks oncogenic YAP/TAZ signaling and overcomes KRAS G12C inhibitor resistance TJ Hagenbeek, JR Zbieg, M Hafner, R Mroue, JA Lacap, NM Sodir, ... Nature Cancer 4 (6), 812-828, 2023 | 42 | 2023 |
| Design of libraries targeting protein-protein interfaces. D Fry, KS Huang, P Di Lello, P Mohr, K Müller, SS So, T Harada, M Stahl, ... ChemMedChem 8 (5), 726-732, 2013 | 38 | 2013 |
| A conserved amphipathic helix in the N-terminal regulatory region of the papillomavirus E1 helicase is required for efficient viral DNA replication G Morin, A Fradet-Turcotte, P Di Lello, F Bergeron-Labrecque, ... Journal of virology 85 (11), 5287-5300, 2011 | 35 | 2011 |
