The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation G Hansen*, TR Hercus*, BJ McClure, FC Stomski, M Dottore, J Powell, ... Cell 134 (3), 496-507, 2008 | 360 | 2008 |
Site-specific serine phosphorylation of the IL-3 receptor is required for hemopoietic cell survival MA Guthridge, FC Stomski, EF Barry, W Winnall, JM Woodcock, ... Molecular cell 6 (1), 99-108, 2000 | 120 | 2000 |
Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common β-chain bound to an antagonist J Rossjohn, WJ McKinstry, JM Woodcock, BJ McClure, TR Hercus, ... Blood, The Journal of the American Society of Hematology 95 (8), 2491-2498, 2000 | 109 | 2000 |
The phosphoserine-585–dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-κB and induction of bcl-2 MA Guthridge, EF Barry, FA Felquer, BJ McClure, FC Stomski, ... Blood 103 (3), 820-827, 2004 | 101 | 2004 |
Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch MA Guthridge, JA Powell, EF Barry, FC Stomski, BJ McClure, H Ramshaw, ... The EMBO Journal 25 (3), 479-489, 2006 | 97 | 2006 |
The human granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor exists as a preformed receptor complex that can be activated by GM-CSF, interleukin-3, or interleukin-5 JM Woodcock, BJ McClure, FC Stomski, MJ Elliott, CJ Bagley, AF Lopez Blood, The Journal of the American Society of Hematology 90 (8), 3005-3017, 1997 | 88 | 1997 |
Simultaneous antagonism of interleukin-5, granulocyte-macrophage colony-stimulating factor, and interleukin-3 stimulation of human eosinophils by targetting the common cytokine … Q Sun, K Jones, B McClure, B Cambareri, B Zacharakis, PO Iversen, ... Blood, The Journal of the American Society of Hematology 94 (6), 1943-1951, 1999 | 76 | 1999 |
Expression profiling of a hemopoietic cell survival transcriptome implicates osteopontin as a functional prognostic factor in AML JA Powell, D Thomas, EF Barry, CH Kok, BJ McClure, A Tsykin, LB To, ... Blood, The Journal of the American Society of Hematology 114 (23), 4859-4870, 2009 | 70 | 2009 |
High prevalence of relapse in children with Philadelphia-like acute lymphoblastic leukemia despite risk-adapted treatment SL Heatley, T Sadras, CH Kok, E Nievergall, K Quek, P Dang, B McClure, ... Haematologica 102 (12), e490, 2017 | 59 | 2017 |
Dual mechanism of interleukin-3 receptor blockade by an anti-cancer antibody SE Broughton, TR Hercus, MP Hardy, BJ McClure, TL Nero, M Dottore, ... Cell reports 8 (2), 410-419, 2014 | 54 | 2014 |
Molecular assembly of the ternary granulocyte-macrophage colony-stimulating factor receptor complex BJ McClure, TR Hercus, BA Cambareri, JM Woodcock, CJ Bagley, ... Blood, The Journal of the American Society of Hematology 101 (4), 1308-1315, 2003 | 52 | 2003 |
Conformational changes in the GM-CSF receptor suggest a molecular mechanism for affinity conversion and receptor signaling SE Broughton, TR Hercus, TL Nero, M Dottore, BJ McClure, U Dhagat, ... Structure 24 (8), 1271-1281, 2016 | 47 | 2016 |
CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors C Panousis, U Dhagat, KM Edwards, V Rayzman, MP Hardy, H Braley, ... MAbs 8 (3), 436-453, 2016 | 46 | 2016 |
New approaches in the treatment of asthma HS Ramshaw, JM Woodcock, CJ Bagley, BJ McClure, TR Hercus, ... Immunology and cell biology 79 (2), 154-159, 2001 | 46 | 2001 |
KMT2A rearranged acute lymphoblastic leukaemia: Unravelling the genomic complexity and heterogeneity of this high-risk disease MO Forgione, BJ McClure, LN Eadie, DT Yeung, DL White Cancer letters 469, 410-418, 2020 | 42 | 2020 |
Locomotor hyperactivity in 14-3-3ζ KO mice is associated with dopamine transporter dysfunction H Ramshaw, X Xu, EJ Jaehne, P McCarthy, Z Greenberg, E Saleh, ... Translational psychiatry 3 (12), e327-e327, 2013 | 40 | 2013 |
Pre-B acute lymphoblastic leukaemia recurrent fusion, EP300-ZNF384, is associated with a distinct gene expression BJ McClure, SL Heatley, CH Kok, T Sadras, J An, TP Hughes, RB Lock, ... British Journal of cancer 118 (7), 1000-1004, 2018 | 37 | 2018 |
Differential expression of MUC4, GPR110 and IL2RA defines two groups of CRLF2-rearranged acute lymphoblastic leukemia patients with distinct secondary lesions T Sadras, SL Heatley, CH Kok, P Dang, KM Galbraith, BJ McClure, ... Cancer letters 408, 92-101, 2017 | 28 | 2017 |
JAK2 Alterations in Acute Lymphoblastic Leukemia: Molecular Insights for Superior Precision Medicine Strategies CEJ Downes, BJ McClure, DP McDougal, SL Heatley, JB Bruning, ... Frontiers in Cell and Developmental Biology 10, 942053, 2022 | 18 | 2022 |
Outcomes for Australian children with relapsed/refractory acute lymphoblastic leukaemia treated with blinatumomab R Sutton, LD Pozza, SL Khaw, C Fraser, T Revesz, J Chamberlain, ... Pediatric Blood & Cancer 68 (5), e28922, 2021 | 17 | 2021 |