Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism PH Chen, J Wu, CKC Ding, CC Lin, S Pan, N Bossa, Y Xu, WH Yang, ... Cell Death & Differentiation 27 (3), 1008-1022, 2020 | 200 | 2020 |
MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis CKC Ding, J Rose, T Sun, J Wu, PH Chen, CC Lin, WH Yang, KY Chen, ... Nature Metabolism 2 (3), 270-277, 2020 | 141 | 2020 |
Glycosylation of KEAP 1 links nutrient sensing to redox stress signaling PH Chen, TJ Smith, J Wu, PF Siesser, BJ Bisnett, F Khan, M Hogue, ... The EMBO journal 36 (15), 2233-2250, 2017 | 94 | 2017 |
An interferon-β-resistant and NLRP3 inflammasome–independent subtype of EAE with neuronal damage M Inoue, P Chen, S Siecinski, Q Li, C Liu, L Steinman, SG Gregory, ... Nature neuroscience 19 (12), 1599-1609, 2016 | 84 | 2016 |
The Hippo pathway effector YAP promotes ferroptosis via the E3 ligase SKP2 WH Yang, CC Lin, J Wu, PY Chao, K Chen, PH Chen, JT Chi Molecular Cancer Research 19 (6), 1005-1014, 2021 | 77 | 2021 |
Zinc transporter ZIP7 is a novel determinant of ferroptosis PH Chen, J Wu, Y Xu, CKC Ding, AA Mestre, CC Lin, WH Yang, JT Chi Cell death & disease 12 (2), 198, 2021 | 77 | 2021 |
DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway CC Lin, WH Yang, YT Lin, X Tang, PH Chen, CKC Ding, DC Qu, ... Oncogene 40 (11), 2018-2034, 2021 | 63 | 2021 |
Modulation of phosphoprotein activity by phosphorylation targeting chimeras (PhosTACs) PH Chen, Z Hu, E An, I Okeke, S Zheng, X Luo, A Gong, ... ACS chemical biology 16 (12), 2808-2815, 2021 | 58 | 2021 |
Syngeneic murine ovarian cancer model reveals that ascites enriches for ovarian cancer stem-like cells expressing membrane GRP78 L Mo, RE Bachelder, M Kennedy, PH Chen, JT Chi, A Berchuck, ... Molecular cancer therapeutics 14 (3), 747-756, 2015 | 58 | 2015 |
Functional crosstalk among oxidative stress and O-GlcNAc signaling pathways PH Chen, JT Chi, M Boyce Glycobiology 28 (8), 556-564, 2018 | 50 | 2018 |
Breast cancer amplified sequence 2, a novel negative regulator of the p53 tumor suppressor PC Kuo, YP Tsao, HW Chang, PH Chen, CW Huang, ST Lin, YT Weng, ... Cancer research 69 (23), 8877-8885, 2009 | 48 | 2009 |
Targeted dephosphorylation of tau by phosphorylation targeting chimeras (PhosTACs) as a therapeutic modality Z Hu, PH Chen, W Li, T Douglas, J Hines, Y Liu, CM Crews Journal of the American Chemical Society 145 (7), 4045-4055, 2023 | 30 | 2023 |
The intersection of DNA damage response and ferroptosis—a rationale for combination therapeutics PH Chen, WHS Tseng, JT Chi Biology 9 (8), 187, 2020 | 26 | 2020 |
Secreted Frizzled-Related Protein 3 (SFRP3) Is Required for Tumorigenesis of PAX3–FOXO1-Positive Alveolar Rhabdomyosarcoma JJG Kephart, RGJ Tiller, LES Crose, KK Slemmons, PH Chen, AR Hinson, ... Clinical Cancer Research 21 (21), 4868-4880, 2015 | 26 | 2015 |
BCAS2 is essential for Drosophila viability and functions in pre-mRNA splicing PH Chen, CI Lee, YT Weng, WY Tarn, YP Tsao, PC Kuo, PH Hsu, ... Rna 19 (2), 208-218, 2013 | 24 | 2013 |
Conditional knockout of breast carcinoma amplified sequence 2 (BCAS2) in mouse forebrain causes dendritic malformation via β-catenin CW Huang, YW Chen, YR Lin, PH Chen, MH Chou, LJ Lee, PY Wang, ... Scientific reports 6 (1), 34927, 2016 | 14 | 2016 |
BCAS2 Regulates Delta-Notch Signaling Activity through Delta Pre-mRNA Splicing in Drosophila Wing Development MH Chou, YC Hsieh, CW Huang, PH Chen, SP Chan, YP Tsao, HH Lee, ... PLoS One 10 (6), e0130706, 2015 | 14 | 2015 |
Gigaxonin glycosylation regulates intermediate filament turnover and may impact giant axonal neuropathy etiology or treatment PH Chen, J Hu, J Wu, DT Huynh, TJ Smith, S Pan, BJ Bisnett, AB Smith, ... JCI insight 5 (1), 2020 | 13 | 2020 |
Mammalian stringent-like response mediated by the cytosolic NADPH phosphatase MESH1 CKC Ding, J Rose, J Wu, T Sun, KY Chen, PH Chen, E Xu, S Tian, ... Biorxiv, 325266, 2018 | 13 | 2018 |
RssAB signaling coordinates early development of surface multicellularity in Serratia marcescens YH Tsai, JR Wei, CS Lin, PH Chen, S Huang, YC Lin, CF Wei, CC Lu, ... PloS one 6 (8), e24154, 2011 | 13 | 2011 |