Disorder and cysteines in proteins: A design for orchestration of conformational see-saw and modulatory functions AA Bhopatkar, VN Uversky, V Rangachari Progress in molecular biology and translational science 174, 331-373, 2020 | 38 | 2020 |
Granulins modulate liquid–liquid phase separation and aggregation of the prion-like C-terminal domain of the neurodegeneration-associated protein TDP-43 AA Bhopatkar, VN Uversky, V Rangachari Journal of Biological Chemistry 295 (8), 2506-2519, 2020 | 34 | 2020 |
Charge and redox states modulate granulin—TDP-43 coacervation toward phase separation or aggregation AA Bhopatkar, S Dhakal, HG Abernathy, SE Morgan, V Rangachari Biophysical journal 121 (11), 2107-2126, 2022 | 13 | 2022 |
Flanking regions, amyloid cores, and polymorphism: the potential interplay underlying structural diversity AA Bhopatkar, R Kayed Journal of Biological Chemistry 299 (9), 2023 | 10 | 2023 |
Cysteine-rich granulin-3 rapidly promotes amyloid-β fibrils in both redox states AA Bhopatkar, G Ghag, LM Wolf, DN Dean, MA Moss, V Rangachari Biochemical Journal 476 (5), 859-873, 2019 | 10 | 2019 |
Are granulins copper sequestering proteins? AA Bhopatkar, V Rangachari Proteins: Structure, Function, and Bioinformatics 89 (4), 450-461, 2021 | 8 | 2021 |
MAPT mutations associated with familial tauopathies lead to formation of conformationally distinct oligomers that have cross‐seeding ability AA Bhopatkar, N Bhatt, MA Haque, R Xavier, L Fung, C Jerez, R Kayed Protein Science 33 (9), e5099, 2024 | 1 | 2024 |
Granulins modulate liquid-liquid phase separation and aggregation of TDP-43 C-terminal domain AA Bhopatkar, VN Uversky, V Rangachari bioRxiv, 812115, 2019 | 1 | 2019 |
Combination of reduced uterine perfusion pressure and leptin infusion as a novel model of preeclampsia AA Bhopatkar, S Mandal, JM Williams American Journal of Physiology-Heart and Circulatory Physiology 327 (2 …, 2024 | | 2024 |
Time restricted feeding improves insulin resistance and reduces progressive proteinuria in young obese Dahl salt-sensitive rats prior to puberty S Mandal, AA Bhopatkar, L Evans, A Johnson, US Ekperikpe, JM Williams Physiology 39 (S1), 1935, 2024 | | 2024 |
Kidney disease associated with pre-pubertal obesity initiates pathological alterations in the brain of Dahl salt-sensitive rats AA Bhopatkar, S Mandal, T Johnson, JM Williams Physiology 39 (S1), 467, 2024 | | 2024 |
Molecular Dynamics Simulations Uncovering the Key Stabilizing Interactions in the p53 Tetramerization Domain M Demny, AA Bhopatkar, A Vlachou, R Kayed, P Tamamis 2023 AIChE Annual Meeting, 2023 | | 2023 |
Abatacept decreases renal T-cell infiltration and renal inflammation and ameliorates progressive renal injury in obese Dahl salt-sensitive rats before puberty US Ekperikpe, S Mandal, AA Bhopatkar, CA Shields, CA Coley, ... Journal of Cardiovascular Pharmacology, 10.1097, 2022 | | 2022 |
Granulins modulate liquid-liquid phase separation or aggregation of prion-like domain of TDP-43 by electrostatic interactions and the redox state of cysteines A Bhopatkar, S Dhakal, V Rangachari Biophysical Journal 121 (3), 474a, 2022 | | 2022 |
Cytoplasmic Colocalization of Granulins and TDP-43 Prion-like Domain Involves Electrostatically Driven Coacervation Tuned by the Redox State of Cysteines AA Bhopatkar, S Dhakal, V Rangachari bioRxiv, 2021.06. 25.449959, 2021 | | 2021 |
Granulins in Norm and Neurodegenerative Pathologies A Bhopatkar | | 2021 |
Cysteine-Rich Granulin-3 Rapidly Promotes Aggregation of Amyloid-Beta in Both Redox States AA Bhopatkar, G Ghag, LM Wolf, DN Dean, MA Moss, V Rangachari Biophysical Journal 116 (3), 351a, 2019 | | 2019 |