| A metabolic stress-inducible miR-34a-HNF4α pathway regulates lipid and lipoprotein metabolism Y Xu, M Zalzala, J Xu, Y Li, L Yin, Y Zhang Nature communications 6, 7466, 2015 | 233 | 2015 |
| Bile acid receptors in non-alcoholic fatty liver disease Y Li, K Jadhav, Y Zhang Biochemical pharmacology 86 (11), 1517-1524, 2013 | 157 | 2013 |
| Hepatic carboxylesterase 1 is essential for both normal and farnesoid X receptor‐controlled lipid homeostasis J Xu, Y Li, WD Chen, Y Xu, L Yin, X Ge, K Jadhav, L Adorini, Y Zhang Hepatology 59 (5), 1761-1771, 2014 | 133 | 2014 |
| Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice Y Li, M Zalzala, K Jadhav, Y Xu, T Kasumov, L Yin, Y Zhang Hepatology 63 (6), 1860-1874, 2016 | 128 | 2016 |
| Mouse-Human Experimental Epigenetic Analysis Unmasks Dietary Targets and Genetic Liability for Diabetic Phenotypes ML Multhaup, MM Seldin, AE Jaffe, X Lei, H Kirchner, P Mondal, Y Li, ... Cell metabolism 21 (1), 138-149, 2015 | 121 | 2015 |
| Novel small-molecule PGC-1α transcriptional regulator with beneficial effects on diabetic db/db mice LN Zhang, HY Zhou, YY Fu, YY Li, F Wu, M Gu, LY Wu, CM Xia, TC Dong, ... Diabetes 62 (4), 1297-1307, 2013 | 112 | 2013 |
| Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR K Jadhav, Y Xu, Y Xu, Y Li, J Xu, Y Zhu, L Adorini, YK Lee, T Kasumov, ... Molecular Metabolism, 2018 | 106 | 2018 |
| 8, 8-Dimethyldihydroberberine with improved bioavailability and oral efficacy on obese and diabetic mouse models Z Cheng, AF Chen, F Wu, L Sheng, HK Zhang, M Gu, YY Li, LN Zhang, ... Bioorganic & medicinal chemistry 18 (16), 5915-5924, 2010 | 79 | 2010 |
| Development of novel alkene oxindole derivatives as orally efficacious AMP-activated protein kinase activators LF Yu, YY Li, MB Su, M Zhang, W Zhang, LN Zhang, T Pang, RT Zhang, ... ACS medicinal chemistry letters 4 (5), 475-480, 2013 | 78 | 2013 |
| Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis RC Riddle, JL Frey, RE Tomlinson, M Ferron, Y Li, DJ DiGirolamo, ... Molecular and cellular biology 34 (10), 1850-1862, 2014 | 66 | 2014 |
| Pancreatic β-cell response to increased metabolic demand and to pharmacologic secretagogues requires EPAC2A WJ Song, P Mondal, Y Li, SE Lee, MA Hussain Diabetes 62 (8), 2796-807, 2013 | 66 | 2013 |
| Novel small-molecule AMPK activator orally exerts beneficial effects on diabetic db/db mice YY Li, LF Yu, LN Zhang, BY Qiu, MB Su, F Wu, DK Chen, T Pang, M Gu, ... Toxicology and applied pharmacology 273 (2), 325-334, 2013 | 65 | 2013 |
| High-throughput assay for modulators of mitochondrial membrane potential identifies a novel compound with beneficial effects on db/db mice BY Qiu, N Turner, YY Li, M Gu, MW Huang, F Wu, T Pang, FJ Nan, JM Ye, ... diabetes 59 (1), 256-265, 2010 | 51 | 2010 |
| Hepatocyte ATF3 protects against atherosclerosis by regulating HDL and bile acid metabolism Y Xu, Y Li, K Jadhav, X Pan, Y Zhu, S Hu, S Chen, L Chen, Y Tang, ... Nature Metabolism 3 (1), 59-74, 2021 | 44 | 2021 |
| Discovery of novel PTP1B inhibitors with antihyperglycemic activity Z Liu, Q Chai, Y Li, Q Shen, L Ma, L Zhang, X Wang, L Sheng, J Li, J Li, ... Acta Pharmacologica Sinica 31 (8), 1005-1012, 2010 | 44 | 2010 |
| Carboxylesterase 1 Is Regulated by Hepatocyte Nuclear Factor 4α and Protects Against Alcohol-and MCD diet-induced Liver Injury J Xu, Y Xu, Y Li, K Jadhav, M You, L Yin, Y Zhang Scientific Reports 6, 24277, 2016 | 41 | 2016 |
| Hepatic Carboxylesterase 1 Is Induced by Glucose and Regulates Postprandial Glucose Levels J Xu, L Yin, Y Xu, Y Li, M Zalzala, G Cheng, Y Zhang PloS one 9 (10), e109663, 2014 | 40 | 2014 |
| Novel small-molecule AMP-activated protein kinase allosteric activator with beneficial effects in db/db mice LN Zhang, L Xu, HY Zhou, LY Wu, YY Li, T Pang, CM Xia, BY Qiu, M Gu, ... PloS one 8 (8), e72092, 2013 | 36 | 2013 |
| Lipocalin‐2 Protects Against Diet‐Induced Nonalcoholic Fatty Liver Disease by Targeting Hepatocytes Y Xu, Y Zhu, K Jadhav, Y Li, H Sun, L Yin, T Kasumov, X Chen, Y Zhang Hepatology Communications, 2019 | 30 | 2019 |
| Synthesis of (S)-,(R)-, and (rac)-2-amino-3, 3-bis (4-fluorophenyl) propanoic acids and an evaluation of the DPP IV inhibitory activity of Denagliptin diastereomers G Deng, D Ye, Y Li, L He, Y Zhou, J Wang, J Li, H Jiang, H Liu Tetrahedron 64 (46), 10512-10516, 2008 | 27 | 2008 |
