Original multivalent copper (II)-conjugated phosphorus dendrimers and corresponding mononuclear copper (II) complexes with antitumoral activities N El Brahmi, S El Kazzouli, SM Mignani, EM Essassi, G Aubert, R Laurent, ... Molecular Pharmaceutics 10 (4), 1459-1464, 2013 | 114 | 2013 |
Advances in direct C–H arylation of 5, 5-6, 5-and 6, 6-fused-heterocycles containing heteroatoms (N, O, S) S El Kazzouli, J Koubachi, N El Brahmi, G Guillaumet RSC advances 5 (20), 15292-15327, 2015 | 99 | 2015 |
Anti-inflammatory effect of anti-TNF-α SiRNA cationic phosphorus dendrimer nanocomplexes administered intranasally in a murine acute lung injury model A Bohr, N Tsapis, I Andreana, A Chamarat, C Foged, C Delomenie, ... Biomacromolecules 18 (8), 2379-2388, 2017 | 91 | 2017 |
Anticancer copper (II) phosphorus dendrimers are potent proapoptotic Bax activators S Mignani, N El Brahmi, L Eloy, J Poupon, V Nicolas, A Steinmetz, ... European Journal of Medicinal Chemistry 132, 142-156, 2017 | 83 | 2017 |
Original multivalent gold (III) and dual gold (III)–copper (II) conjugated phosphorus dendrimers as potent antitumoral and antimicrobial agents SM Mignani, N El Brahmi, S El Kazzouli, R Laurent, S Ladeira, ... molecular pharmaceutics 14 (11), 4087-4097, 2017 | 70 | 2017 |
From metallodrugs to metallodendrimers for nanotherapy in oncology: a concise overview S El Kazzouli, N El Brahmi, S Mignani, M Bousmina, M Zablocka, ... Current medicinal chemistry 19 (29), 4995-5010, 2012 | 62 | 2012 |
A novel class of ethacrynic acid derivatives as promising drug-like potent generation of anticancer agents with established mechanism of action S Mignani, N El Brahmi, S El Kazzouli, L Eloy, D Courilleau, J Caron, ... European Journal of Medicinal Chemistry 122, 656-673, 2016 | 41 | 2016 |
Synthesis of onion‐peel nanodendritic structures with sequential functional phosphorus diversity N Katir, N El Brahmi, A El Kadib, S Mignani, AM Caminade, M Bousmina, ... Chemistry–A European Journal 21 (17), 6400-6408, 2015 | 41 | 2015 |
Investigations on dendrimer space reveal solid and liquid tumor growth-inhibition by original phosphorus-based dendrimers and the corresponding monomers and dendrons with … N El Brahmi, SM Mignani, J Caron, S El Kazzouli, MM Bousmina, ... Nanoscale 7 (9), 3915-3922, 2015 | 41 | 2015 |
Neutral high-generation phosphorus dendrimers inhibit macrophage-mediated inflammatory response in vitro and in vivo I Posadas, L Romero-Castillo, N El Brahmi, D Manzanares, S Mignani, ... Proceedings of the National Academy of Sciences 114 (37), E7660-E7669, 2017 | 40 | 2017 |
Comparative EPR studies of Cu (II)-conjugated phosphorous-dendrimers in the absence and presence of normal and cancer cells MF Ottaviani, N El Brahmi, M Cangiotti, C Coppola, F Buccella, T Cresteil, ... RSC advances 4 (69), 36573-36583, 2014 | 36 | 2014 |
Synthesis, characterization and biological properties of new hybrid carbosilane–viologen–phosphorus dendrimers S Moreno, A Szwed, N El Brahmi, K Milowska, J Kurowska, ... RSC Advances 5 (33), 25942-25958, 2015 | 30 | 2015 |
Copper in dendrimer synthesis and applications of copper–dendrimer systems in catalysis: a concise overview N El Brahmi, S El Kazzouli, S Mignani, M Bousmina, JP Majoral Tetrahedron 69 (15), 3103-3133, 2013 | 29 | 2013 |
Dendrimer for templating the growth of porous catechol-coordinated titanium dioxide frameworks: toward hemocompatible nanomaterials N Katir, N Marcotte, S Michlewska, M Ionov, N El Brahmi, M Bousmina, ... ACS Applied Nano Materials 2 (5), 2979-2990, 2019 | 26 | 2019 |
Elucidating the role of surface chemistry on cationic phosphorus dendrimer–siRNA complexation MA Deriu, N Tsapis, M Noiray, G Grasso, N El Brahmi, S Mignani, ... Nanoscale 10 (23), 10952-10962, 2018 | 26 | 2018 |
Orthogonal synthesis of covalent polydendrimer frameworks by fusing classical and onion-peel phosphorus-based dendritic units N Katir, N El Brahmi, N Marcotte, JP Majoral, M Bousmina, A El Kadib Macromolecules 49 (16), 5796-5805, 2016 | 16 | 2016 |
Synthesis, Anticancer Activities and Molecular Docking Studies of a Novel Class of 2-Phenyl-5,6,7,8-tetrahydroimidazo [1,2-b]pyridazine Derivatives Bearing … O Bourzikat, A El Abbouchi, H Ghammaz, N El Brahmi, E El Fahime, ... Molecules 27 (16), 5238, 2022 | 15 | 2022 |
Oxidative alkenylation of fused bicyclic heterocycles J Koubachi, N El Brahmi, G Guillaumet, S El Kazzouli European Journal of Organic Chemistry 2019 (15), 2568-2586, 2019 | 15 | 2019 |
Synthesis and biological evaluation of ethacrynic acid derivatives bearing sulfonamides as potent anti-cancer agents A El Abbouchi, N El Brahmi, MA Hiebel, J Bignon, G Guillaumet, ... Bioorganic & Medicinal Chemistry Letters 30 (19), 127426, 2020 | 14 | 2020 |
First-in-class combination therapy of a copper (II) metallo-phosphorus dendrimer with cytotoxic agents S Mignani, N El Brahmi, T Cresteil, JP Majoral Oncology 94 (5), 324-328, 2018 | 14 | 2018 |