| Recent applications of multicomponent reactions in medicinal chemistry P Slobbe, E Ruijter, RVA Orru MedChemComm 3 (10), 1189-1218, 2012 | 508 | 2012 |
| PET imaging with small-molecule tyrosine kinase inhibitors: TKI-PET P Slobbe, AJ Poot, AD Windhorst, GAMS van Dongen Drug discovery today 17 (21-22), 1175-1187, 2012 | 80 | 2012 |
| A comparative PET imaging study with the reversible and irreversible EGFR tyrosine kinase inhibitors [11C]erlotinib and [18F]afatinib in lung cancer-bearing mice P Slobbe, AD Windhorst, M Stigter-van Walsum, EF Smit, HG Niessen, ... EJNMMI research 5, 1-12, 2015 | 54 | 2015 |
| Development of [18F] afatinib as new TKI-PET tracer for EGFR positive tumors P Slobbe, AD Windhorst, M Stigter-van Walsum, RC Schuit, EF Smit, ... Nuclear medicine and biology 41 (9), 749-757, 2014 | 49 | 2014 |
| Imaging of TKI–Target Interactions for Personalized Cancer Therapy AJ Poot, P Slobbe, NH Hendrikse, AD Windhorst, G van Dongen Clinical Pharmacology & Therapeutics 93 (3), 239-241, 2013 | 22 | 2013 |
| Synthesis and evaluation of a selective fluorogenic Pup derived assay reagent for Dop, a potential drug target in Mycobacterium tuberculosis R Merkx, KE Burns, P Slobbe, F El Oualid, D El Atmioui, KH Darwin, ... ChemBioChem 13 (14), 2056, 2012 | 15 | 2012 |
| Two anti-angiogenic TKI-PET tracers,[11C] axitinib and [11C] nintedanib: radiosynthesis, in vivo metabolism and initial biodistribution studies in rodents P Slobbe, AJ Poot, R Haumann, RC Schuit, AD Windhorst, ... Nuclear medicine and biology 43 (10), 612-624, 2016 | 13 | 2016 |
| Development of [11C] vemurafenib employing a carbon-11 carbonylative Stille coupling and preliminary evaluation in mice bearing melanoma tumor xenografts P Slobbe, AD Windhorst, K Adamzek, M Bolijn, RC Schuit, ... Oncotarget 8 (24), 38337, 2017 | 10 | 2017 |
| Diastereoselective one-pot synthesis of tetrafunctionalized 2-imidazolines GV Janssen, P Slobbe, M Mooijman, A Kruithof, AW Ehlers, CF Guerra, ... The Journal of Organic Chemistry 79 (11), 5219-5226, 2014 | 8 | 2014 |
| Synthesis of Enaminones by a Palladium-Catalyzed Four-Component Carbonylative Addition Reaction L Wang, J Ma, X Chen, X Zhou Synlett 28 (19), 2680-2684, 2017 | 6 | 2017 |
| MedChemComm 2012, 3, 1189; b) A. Dçmling, W. Wang, K. Wang P Slobbe, E Ruijter, RVA Orru Chem. Rev 112, 3083, 2012 | 5 | 2012 |
| Radiolabeled tyrosine kinase inhibitors for drug development and cancer treatment: TKI-PET P Slobbe | 2 | 2016 |
| Radiolabeled quinazoline derivatives P Slobbe, AJ Poot, AAMS Van Dongen, H Niessen, AD Windhorst US Patent App. 14/765,042, 2015 | 2 | 2015 |
| [11C] nintedanib as TKI-PET tracer for angiogenesis imaging in vivo. A Poot, P Slobbe, A Windhorst, R Haumann, R Schuit, G Van Dongen Journal of Nuclear Medicine 57 (supplement 2), 1153-1153, 2016 | 1 | 2016 |
| Development of an LC-MS method to analyze the primary metabolite of [C-11] nintedanib in vivo P Slobbe, AD Windhorst, R Haumann, R Schuit, GA van Dongen, AJ Poot JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 58, S30-S30, 2015 | 1 | 2015 |
| Synthesis of [C-11] vemurafenib via a unique [C-11] CO carbonylative Stille coupling to image V600E mutated B-Raf in cancer. P Slobbe, AD Windhorst, GA van Dongen, AJ Poot JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS 58, S281-S281, 2015 | 1 | 2015 |
| Development of [11C] vemurafenib employing a carbon-11 carbonylative Stille coupling for the in vivo detection of V600E mutated BRAF P Slobbe, AD Windhorst, WA Adamzek, M Bolijn, RC Schuit, ... Paul Slobbe, 179, 2016 | | 2016 |
| A comparative preclinical PET imaging study between [11C] erlotinib and [18F] afatinib P Slobbe, A Windhorst, MS Walsum, R Schuit, E Smit, H Niessen, ... Cancer Research 74 (19_Supplement), 113-113, 2014 | | 2014 |
| Development of [11C] nintedanib as potential TKI-PET tracer for angiogenesis imaging AJ Poot, P Slobbe, G Van Dongen, AD Windhorst EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 40, S317-S317, 2013 | | 2013 |
| [18F] afatinib as imaging biomarker of EGFR tyrosine kinase in NSCLC P Slobbe, AD Windhorst, M Stigter-van Walsum, H Niessen, ... EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 40, S199-S199, 2013 | | 2013 |
