VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing DC Koboldt, Q Zhang, DE Larson, D Shen, MD McLellan, L Lin, CA Miller, ... Genome research 22 (3), 568-576, 2012 | 4881 | 2012 |
The genomic landscapes of human breast and colorectal cancers LD Wood, DW Parsons, S Jones, J Lin, T Sjoblom, RJ Leary, D Shen, ... Science 318 (5853), 1108-1113, 2007 | 3758 | 2007 |
Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing L Ding, TJ Ley, DE Larson, CA Miller, DC Koboldt, JS Welch, JK Ritchey, ... Nature 481 (7382), 506-510, 2012 | 2532 | 2012 |
Detection and quantification of mutations in the plasma of patients with colorectal tumors F Diehl, M Li, D Dressman, Y He, D Shen, S Szabo, LA Diaz Jr, ... Proceedings of the National Academy of Sciences 102 (45), 16368-16373, 2005 | 1525 | 2005 |
Genome remodelling in a basal-like breast cancer metastasis and xenograft LI Ding, MJ Ellis, S Li, DE Larson, K Chen, JW Wallis, CC Harris, ... Nature 464 (7291), 999-1005, 2010 | 1351 | 2010 |
Whole-genome analysis informs breast cancer response to aromatase inhibition MJ Ellis, L Ding, D Shen, J Luo, VJ Suman, JW Wallis, BA Van Tine, ... Nature 486 (7403), 353-360, 2012 | 1206 | 2012 |
Clonal architecture of secondary acute myeloid leukemia MJ Walter, D Shen, L Ding, J Shao, DC Koboldt, K Chen, DE Larson, ... New England Journal of Medicine 366 (12), 1090-1098, 2012 | 977 | 2012 |
Activating HER2 mutations in HER2 gene amplification negative breast cancer R Bose, SM Kavuri, AC Searleman, W Shen, D Shen, DC Koboldt, ... Cancer discovery 3 (2), 224-237, 2013 | 898 | 2013 |
Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia TN Wong, G Ramsingh, AL Young, CA Miller, W Touma, JS Welch, ... Nature 518 (7540), 552-555, 2015 | 827 | 2015 |
Endocrine-therapy-resistant ESR1 variants revealed by genomic characterization of breast-cancer-derived xenografts S Li, D Shen, J Shao, R Crowder, W Liu, A Prat, X He, S Liu, J Hoog, C Lu, ... Cell reports 4 (6), 1116-1130, 2013 | 697 | 2013 |
Recurrent DNMT3A mutations in patients with myelodysplastic syndromes MJ Walter, L Ding, D Shen, J Shao, M Grillot, M McLellan, R Fulton, ... Leukemia 25 (7), 1153-1158, 2011 | 687 | 2011 |
Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes TA Graubert, D Shen, L Ding, T Okeyo-Owuor, CL Lunn, J Shao, K Krysiak, ... Nature genetics 44 (1), 53-57, 2012 | 649 | 2012 |
Mutational analysis of the tyrosine phosphatome in colorectal cancers Z Wang, D Shen, DW Parsons, A Bardelli, J Sager, S Szabo, J Ptak, ... Science 304 (5674), 1164-1166, 2004 | 645 | 2004 |
Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers TD Barber, K McManus, KWY Yuen, M Reis, G Parmigiani, D Shen, ... Proceedings of the National Academy of Sciences 105 (9), 3443-3448, 2008 | 542 | 2008 |
Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia JM Klco, CA Miller, M Griffith, A Petti, DH Spencer, S Ketkar-Kulkarni, ... Jama 314 (8), 811-822, 2015 | 381 | 2015 |
Clonal diversity of recurrently mutated genes in myelodysplastic syndromes MJ Walter, D Shen, J Shao, L Ding, BS White, C Kandoth, CA Miller, B Niu, ... Leukemia 27 (6), 1275-1282, 2013 | 327 | 2013 |
Genomic analysis of germ line and somatic variants in familial myelodysplasia/acute myeloid leukemia JE Churpek, K Pyrtel, KL Kanchi, J Shao, D Koboldt, CA Miller, D Shen, ... Blood, The Journal of the American Society of Hematology 126 (22), 2484-2490, 2015 | 266 | 2015 |
Three classes of genes mutated in colorectal cancers with chromosomal instability Z Wang, JM Cummins, D Shen, DP Cahill, PV Jallepalli, TL Wang, ... Cancer research 64 (9), 2998-3001, 2004 | 260 | 2004 |
Identification of a novel TP53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML DC Link, LG Schuettpelz, D Shen, J Wang, MJ Walter, S Kulkarni, ... Jama 305 (15), 1568-1576, 2011 | 210 | 2011 |
A validated prediction tool for initial survivors of in-hospital cardiac arrest PS Chan, JA Spertus, HM Krumholz, RA Berg, Y Li, C Sasson, ... Archives of internal medicine 172 (12), 947-953, 2012 | 170 | 2012 |