Biological activities of plant extracts from Ficus elastica and Selaginella vogelli: An antimalarial, antitrypanosomal and cytotoxity evaluation JEM Teinkela, XS Noundou, EL Nguemfo, F Meyer, R Wintjens, M Isaacs, ... Saudi journal of biological sciences 25 (1), 117-122, 2018 | 54 | 2018 |
Application of the Morita-Baylis-Hillman reaction in the synthesis of 3-[(N-cycloalkylbenzamido) methyl]-2-quinolones as potential HIV-1 integrase inhibitors KC Sekgota, S Majumder, M Isaacs, D Mnkandhla, HC Hoppe, ... Bioorganic chemistry 75, 310-316, 2017 | 51 | 2017 |
Ferrocenyl and organic novobiocin derivatives: Synthesis and their in vitro biological activity M Mbaba, AN Mabhula, N Boel, AL Edkins, M Isaacs, HC Hoppe, ... Journal of inorganic biochemistry 172, 88-93, 2017 | 38 | 2017 |
Novobiocin–ferrocene conjugates possessing anticancer and antiplasmodial activity independent of HSP90 inhibition M Mbaba, JA de la Mare, JN Sterrenberg, D Kajewole, S Maharaj, ... JBIC Journal of Biological Inorganic Chemistry 24, 139-149, 2019 | 29 | 2019 |
Indolyl-3-ethanone-α-thioethers: a promising new class of non-toxic antimalarial agents AL Svogie, M Isaacs, HC Hoppe, SD Khanye, CGL Veale European Journal of Medicinal Chemistry 114, 79-88, 2016 | 26 | 2016 |
Biological activity of plant extracts and isolated compounds from Alchornea laxiflora: Anti-HIV, antibacterial and cytotoxicity evaluation X Siwe-Noundou, DT Ndinteh, DK Olivier, D Mnkandhla, M Isaacs, ... South African Journal of Botany 122, 498-503, 2019 | 24 | 2019 |
Cinnamoyl-oxaborole amides: Synthesis and their in vitro biological activity M Gumbo, RM Beteck, T Mandizvo, R Seldon, DF Warner, HC Hoppe, ... Molecules 23 (8), 2038, 2018 | 21 | 2018 |
In vitro antimalarial, antitrypanosomal and HIV-1 integrase inhibitory activities of two Cameroonian medicinal plants: Antrocaryon klaineanum (Anacardiaceae) and Diospyros … Y Fouokeng, HMF Feusso, JEM Teinkela, XS Noundou, R Wintjens, ... South African journal of botany 122, 510-517, 2019 | 20 | 2019 |
Evaluation of novel N′-(3-hydroxybenzoyl)-2-oxo-2 H-chromene-3-carbohydrazide derivatives as potential HIV-1 integrase inhibitors OJ Jesumoroti, D Mnkandhla, M Isaacs, HC Hoppe, R Klein MedChemComm 10 (1), 80-88, 2019 | 20 | 2019 |
New thiazolidine‐2, 4‐dione derivatives combined with organometallic ferrocene: Synthesis, structure and antiparasitic activity OO Oderinlo, M Tukulula, M Isaacs, HC Hoppe, D Taylor, VJ Smith, ... Applied Organometallic Chemistry 32 (7), e4385, 2018 | 19 | 2018 |
Fungal colonization and enzyme-mediated metabolism of waste coal by Neosartorya fischeri strain ECCN 84 LM Sekhohola, ML Isaacs, AK Cowan Bioscience, Biotechnology, and Biochemistry 78 (10), 1797-1802, 2014 | 19 | 2014 |
Synthesis and antimalarial activity of N-benzylated (N-arylcarbamoyl) alkylphosphonic acid derivatives CM Adeyemi, M Isaacs, D Mnkandhla, HC Hoppe, RWM Krause, PT Kaye Bioorganic & Medicinal Chemistry 24 (23), 6131-6138, 2016 | 18 | 2016 |
Synthesis, structure and in vitro anti-trypanosomal activity of non-toxic arylpyrrole-based chalcone derivatives AI Zulu, OO Oderinlo, C Kruger, M Isaacs, HC Hoppe, VJ Smith, ... Molecules 25 (7), 1668, 2020 | 17 | 2020 |
Synthesis and biological evaluation of 2-chloro-3-[(thiazol-2-yl) amino]-1, 4-naphthoquinones EO Olawode, R Tandlich, E Prinsloo, M Isaacs, H Hoppe, R Seldon, ... Bioorganic & medicinal chemistry letters 29 (13), 1572-1575, 2019 | 17 | 2019 |
Synthesis and evaluation of 3-hydroxy-3-phenylpropanoate ester–AZT conjugates as potential dual-action HIV-1 Integrase and Reverse Transcriptase inhibitors MH Manyeruke, TO Olomola, S Majumder, S Abrahams, M Isaacs, ... Bioorganic & Medicinal Chemistry 23 (24), 7521-7528, 2015 | 17 | 2015 |
Expanding the SAR of nontoxic antiplasmodial indolyl‐3‐ethanone ethers and thioethers MJ Lunga, RL Chisango, C Weyers, M Isaacs, D Taylor, AL Edkins, ... ChemMedChem 13 (13), 1353-1362, 2018 | 16 | 2018 |
Anti-trypanosomal and antimalarial properties of tetralone derivatives and structurally related benzocycloalkanones RM Beteck, LJ Legoabe, M Isaacs, SD Khanye, D Laming, HC Hoppe Medicina 55 (5), 206, 2019 | 15 | 2019 |
Anti-cancer and anti-trypanosomal properties of alkaloids from the root bark of Zanthoxylum leprieurii Guill and Perr FI Eze, X Siwe-Noundou, M Isaacs, S Patnala, PO Osadebe, RWM Krause Tropical Journal of Pharmaceutical Research 19 (11), 2377-2383, 2020 | 13 | 2020 |
Synthesis of N-Substituted phosphoramidic acid esters as “reverse” fosmidomycin analogues CM Adeyemi, HC Hoppe, M Isaacs, R Klein, KA Lobb, PT Kaye Tetrahedron 75 (16), 2371-2378, 2019 | 11 | 2019 |
Antiplasmodial activity of the n-hexane extract from Pleurotus ostreatus (Jacq. Ex. Fr) P. Kumm. OE Afieroho, XS Noundou, CP Onyia, OH Festus, EC Chukwu, ... Turkish Journal of Pharmaceutical Sciences 16 (1), 37, 2019 | 11 | 2019 |