| Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass R Gunaratne, S Kumar, JW Frederiksen, S Stayrook, JL Lohrmann, ... Nature biotechnology 36 (7), 606-613, 2018 | 65 | 2018 |
| Identification of a new exosite involved in catalytic turnover by the streptokinase-plasmin activator complex during human plasminogen activation R Aneja, M Datt, B Singh, S Kumar, G Sahni Journal of biological chemistry 284 (47), 32642-32650, 2009 | 28 | 2009 |
| Mutants of streptokinase and their covalently modified forms S Kumar, N Maheshwari, G Sahni EP Patent EP3124496A1, 2018 | 21* | 2018 |
| Site-Specific Thiol-mediated PEGylation of streptokinase leads to improved properties with clinical potential P Sawhney, S Kumar, N Maheshwari, S Singh Guleria, N Dhar, ... Current pharmaceutical design 22 (38), 5868-5878, 2016 | 19 | 2016 |
| Generation of an anticoagulant aptamer that targets factor V/Va and disrupts the FVa-membrane interaction in normal and COVID-19 patient samples EE Soule, H Yu, L Olson, I Naqvi, S Kumar, S Krishnaswamy, ... Cell Chemical Biology 29 (2), 215-225. e5, 2022 | 7 | 2022 |
| Aptameric hirudins as selective and reversible EXosite-ACTive site (EXACT) inhibitors H Yu, S Kumar, JW Frederiksen, VN Kolyadko, G Pitoc, J Layzer, A Yan, ... Nature Communications 15 (1), 3977, 2024 | 4 | 2024 |
| High resolution X-ray structure of snake venom factor V: evolution of a hemostatic cofactor to a toxin poised to inflict maximal damage to mammalian blood coagulation S Kumar, S Stayrook, JA Huntington, RM Camire, S Krishnaswamy Blood 118 (21), 375, 2011 | 3 | 2011 |
| Thrombin formation S Kumar, S Krishnaswamy Trauma Induced Coagulopathy, 55-74, 2016 | 2 | 2016 |
| Structural basis for the procofactor to cofactor transition in human factor V S Kumar, W Deng, S Stayrook, R Li, RM Camire, S Krishnaswamy Blood 128 (22), 253, 2016 | 1 | 2016 |
| The X-ray structure of a variant of human factor V provides structural insights into the procofactor activation paradox S Kumar, S Stayrook, RM Camire, S Krishnaswamy Blood 126 (23), 121, 2015 | 1 | 2015 |
| New Structural Insights into High Affinity Membrane Binding By Coagulation Factor V/Va S Kumar, S Stayrook, JA Huntington, RM Camire, S Krishnaswamy Blood 124 (21), 4216, 2014 | 1 | 2014 |
| Design of a Superior Factor VIIIa Mimetic By Coupling a Membrane Binding Domain to a Factor IXa Binding Antibody Fragment S Kumar, S Krishnaswamy Blood 142, 22, 2023 | | 2023 |
| X-Ray Structure of Thrombin Bound to a Heterobifunctional Aptamer-Drug Conjugate Reveals the Mechanistic Basis for a Novel Tethered Inhibition Strategy S Kumar, H Yu, BA Sullenger, S Krishnaswamy Blood 140 (Supplement 1), 1668-1669, 2022 | | 2022 |
| Kringles of substrate plasminogen provide a ‘catalytic switch'in plasminogen to plasmin turnover by Streptokinase V Sharma, S Kumar, G Sahni Biochemical Journal 477 (5), 953-970, 2020 | | 2020 |
| Mutants of Streptokinase and their covalently modified forms S Kumar, N Maheshwari, G Sahni US Patent US9115210B2, 2015 | | 2015 |
| X-Ray Structure of an Anticoagulant RNA Aptamer Bound to Factor Xa. Structural Basis for Its Ability to Disrupt Interactions Between Xa and Va within Prothrombinase S Kumar, BA Sullenger, S Stayrook, S Krishnaswamy Blood 124 (21), 4232, 2014 | | 2014 |
