| Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction KM Fujihara, BZ Zhang, TD Jackson, MO Ogunkola, B Nijagal, JV Milne, ... Science Advances 8 (37), eabm9427, 2022 | 42 | 2022 |
| Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome Y Kang, AJ Anderson, TD Jackson, CS Palmer, DP De Souza, ... Elife 8, e48828, 2019 | 41 | 2019 |
| A thiol‐bound drug reservoir enhances APR‐246‐induced mutant p53 tumor cell death S Ceder, SE Eriksson, EH Cheteh, S Dawar, M Corrales Benitez, ... EMBO molecular medicine 13 (2), e10852, 2021 | 39 | 2021 |
| The TIM22 complex mediates the import of sideroflexins and is required for efficient mitochondrial one-carbon metabolism TD Jackson, DH Hock, KM Fujihara, CS Palmer, AE Frazier, YC Low, ... Molecular Biology of the Cell 32 (6), 475-491, 2021 | 34 | 2021 |
| SLC7A11 Is a Superior Determinant of APR-246 (Eprenetapopt) Response than TP53 Mutation Status KM Fujihara, M Corrales Benitez, CS Cabalag, BZ Zhang, HS Ko, DS Liu, ... Molecular cancer therapeutics 20 (10), 1858-1867, 2021 | 30 | 2021 |
| Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module TD Jackson, JJ Crameri, L Muellner-Wong, AE Frazier, CS Palmer, ... Proceedings of the National Academy of Sciences 119 (13), e2115566119, 2022 | 19 | 2022 |
| Opportunities for ferroptosis in cancer therapy KM Fujihara, BZ Zhang, NJ Clemons Antioxidants 10 (6), 986, 2021 | 18 | 2021 |
| Loss of SMAD4 is sufficient to promote tumorigenesis in a model of dysplastic Barrett’s esophagus JR Gotovac, T Kader, JV Milne, KM Fujihara, LE Lara-Gonzalez, ... Cellular and Molecular Gastroenterology and Hepatology 12 (2), 689-713, 2021 | 18 | 2021 |
| Molecular comparison of interval and screen‐detected breast cancers D Cheasley, N Li, SM Rowley, K Elder, GB Mann, S Loi, P Savas, ... The Journal of Pathology 248 (2), 243-252, 2019 | 18 | 2019 |
| Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells S Ceder, SE Eriksson, YY Liang, EH Cheteh, SM Zhang, KM Fujihara, ... Cell Death & Disease 12 (7), 709, 2021 | 17 | 2021 |
| Potential clinical utility of a targeted circulating tumor DNA assay in esophageal adenocarcinoma CS Cabalag, M Yates, MB Corrales, P Yeh, SQ Wong, BZ Zhang, ... Annals of surgery 276 (2), e120-e126, 2022 | 14 | 2022 |
| TGF-beta signaling and its targeted therapy in gastrointestinal cancers JR Gotovac, KM Fujihara, WA Phillips, NJ Clemons Discovery Medicine 26 (142), 103-112, 2018 | 14 | 2018 |
| Multiparametric high-content cell painting identifies copper ionophores as selective modulators of esophageal cancer phenotypes RE Hughes, RJR Elliott, X Li, AF Munro, A Makda, RN Carter, NM Morton, ... ACS Chemical Biology 17 (7), 1876-1889, 2022 | 13 | 2022 |
| Allosteric regulation of CAD modulates de novo pyrimidine synthesis during the cell cycle J Shin, H Mir, MA Khurram, KM Fujihara, BD Dynlacht, TJ Cardozo, ... Nature metabolism 5 (2), 277-293, 2023 | 12 | 2023 |
| Targeting MDM4 as a novel therapeutic approach in prostate cancer independent of p53 status JO Mejía-Hernández, D Raghu, F Caramia, N Clemons, K Fujihara, ... Cancers 14 (16), 3947, 2022 | 7 | 2022 |
| The TIM22 complex regulates mitochondrial one-carbon metabolism by mediating the import of Sideroflexins TD Jackson, D Hock, CS Palmer, Y Kang, KM Fujihara, NJ Clemons, ... bioRxiv, 2020.02. 06.937920, 2020 | 7 | 2020 |
| Bridging the molecular divide: alcohol‐induced downregulation of PAX9 and tumour development KM Fujihara, NJ Clemons The Journal of pathology 244 (4), 386-388, 2018 | 7 | 2018 |
| Genome-wide CRISPR screens reveal APR-246 (Eprenetapopt) triggers ferroptosis and inhibits iron-sulfur cluster biogenesis KM Fujihara, B Zhang, TD Jackson, B Nijiagel, CS Ang, I Nikolic, V Sutton, ... bioRxiv, 2020.11. 29.398867, 2020 | 6 | 2020 |
| Tumor-infiltrating neutrophils after neoadjuvant therapy are associated with poor prognosis in esophageal cancer CS Cabalag, OWJ Prall, J Ciciulla, LA Galea, N Thio, M Jayawardana, ... Annals of Surgical Oncology 30 (3), 1614-1625, 2023 | 5 | 2023 |
| Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation JV Milne, BZ Zhang, KM Fujihara, S Dawar, WA Phillips, NJ Clemons Scientific Reports 11 (1), 4480, 2021 | 5 | 2021 |
