Native chemical ligation and extended methods: mechanisms, catalysis, scope, and limitations V Agouridas, O El Mahdi, V Diemer, M Cargoet, JCM Monbaliu, O Melnyk Chemical reviews 119 (12), 7328-7443, 2019 | 476 | 2019 |
A statistical view of protein chemical synthesis using NCL and extended methodologies V Agouridas, O El Mahdi, M Cargoët, O Melnyk Bioorganic & Medicinal Chemistry 25 (18), 4938-4945, 2017 | 76 | 2017 |
Total synthesis of discodermolide: optimization of the effective synthetic route E de Lemos, FH Porée, A Bourin, J Barbion, E Agouridas, MI Lannou, ... Chemistry–A European Journal 14 (35), 11092-11112, 2008 | 57 | 2008 |
Design and synthesis of ansamycin antibiotics IE Wrona, V Agouridas, JS Panek Comptes Rendus Chimie 11 (11-12), 1483-1522, 2008 | 45 | 2008 |
From protein total synthesis to peptide transamidation and metathesis: playing with the reversibility of N, S-acyl or N, Se-acyl migration reactions O Melnyk, V Agouridas Current Opinion in Chemical Biology 22, 137-145, 2014 | 36 | 2014 |
Chemical Protein Synthesis in Medicinal Chemistry: Miniperspective V Agouridas, O El Mahdi, O Melnyk Journal of Medicinal Chemistry 63 (24), 15140-15152, 2020 | 28 | 2020 |
M. Cargo t, J.-CM Monbaliu, O. Melnyk V Agouridas, O El Mahdi, V Diemer Chem. Rev 119, 7328-7443, 2019 | 27 | 2019 |
A cysteine selenosulfide redox switch for protein chemical synthesis V Diemer, N Ollivier, B Leclercq, H Drobecq, J Vicogne, V Agouridas, ... Nature Communications 11 (1), 2558, 2020 | 25 | 2020 |
Catalysis of Thiol–Thioester Exchange by Water-Soluble Alkyldiselenols Applied to the Synthesis of Peptide Thioesters and SEA-Mediated Ligation M Cargoët, V Diemer, B Snella, R Desmet, A Blanpain, H Drobecq, ... The Journal of organic chemistry 83 (20), 12584-12594, 2018 | 25 | 2018 |
Cyclic Sulfamidates as Vehicles for the Synthesis of Poly- and Diversely Substituted Benzosultams via Unusual S(O)2−O Bond Cleavage M Lorion, V Agouridas, A Couture, E Deniau, P Grandclaudon Organic Letters 12 (6), 1356-1359, 2010 | 24 | 2010 |
Loss of antagonistic activity of tamoxifen by replacement of one N-methyl of its side chain by fluorinated residues V Agouridas, I Laı, A Cleeren, E Kizilian, E Magnier, JC Blazejewski, ... Bioorganic & medicinal chemistry 14 (22), 7531-7538, 2006 | 22 | 2006 |
Strategies and open questions in solid-phase protein chemical synthesis V Agouridas, V Diemer, O Melnyk Current Opinion in Chemical Biology 58, 1-9, 2020 | 21 | 2020 |
Native chemical ligation at serine revisited B Snella, V Diemer, H Drobecq, V Agouridas, O Melnyk Organic Letters 20 (23), 7616-7619, 2018 | 16 | 2018 |
Pedal to the metal: The homogeneous catalysis of the native chemical ligation reaction V Diemer, O Firstova, V Agouridas, O Melnyk Chemistry–A European Journal 28 (16), e202104229, 2022 | 15 | 2022 |
Conception, synthesis, and biological evaluation of original discodermolide analogues E de Lemos, E Agouridas, G Sorin, A Guerreiro, A Commerçon, ... Chemistry–A European Journal 17 (36), 10123-10134, 2011 | 15 | 2011 |
Effect of fluorination on the pharmacological profile of 11β isomers of fulvestrant in breast carcinoma cells V Agouridas, E Magnier, JC Blazejewski, I Laïos, A Cleeren, D Nonclercq, ... Journal of medicinal chemistry 52 (3), 883-887, 2009 | 15 | 2009 |
Cesium carbonate mediated aryl triflate esters’ deprotection AE Green, V Agouridas, E Deniau Tetrahedron Letters 54 (51), 7078-7079, 2013 | 14 | 2013 |
A highly diastereoselective synthesis of isoindolinone-centered Meyers’ tetracyclic lactams. Application to the asymmetric synthesis of 3-alkylisoindolinones V Agouridas, F Capet, A Couture, E Deniau, P Grandclaudon Tetrahedron: Asymmetry 22 (13), 1441-1447, 2011 | 14 | 2011 |
Total chemical synthesis of proteins A Brik, P Dawson, L Liu John Wiley & Sons, 2021 | 13 | 2021 |
Synthesis and cytotoxic evaluation of cis-locked and constrained analogues of combretastatin and combretastatin A4 M Lorion, V Agouridas, A Couture, E Deniau, P Grandclaudon Tetrahedron Letters 51 (39), 5146-5149, 2010 | 12 | 2010 |