Inhibition of human pancreatic ribonuclease by the human ribonuclease inhibitor protein RJ Johnson, JG McCoy, CA Bingman, GN Phillips Jr, RT Raines Journal of molecular biology 368 (2), 434-449, 2007 | 202 | 2007 |
Cytotoxic ribonucleases: the dichotomy of Coulombic forces RJ Johnson, TY Chao, LD Lavis, RT Raines Biochemistry 46 (36), 10308-10316, 2007 | 73 | 2007 |
Implementation of a collaborative series of classroom-based undergraduate research experiences spanning chemical biology, biochemistry, and neurobiology JR Kowalski, GC Hoops, RJ Johnson CBE—Life Sciences Education 15 (4), ar55, 2016 | 62 | 2016 |
Microbial esterases and ester prodrugs: An unlikely marriage for combating antibiotic resistance EM Larsen, RJ Johnson Drug development research 80 (1), 33-47, 2019 | 51 | 2019 |
Structure of the U6 RNA intramolecular stem–loop harboring an SP-phosphorothioate modification NJ Reiter, LJ Nikstad, AM Allmann, RJ Johnson, SE Butcher Rna 9 (5), 533-542, 2003 | 50 | 2003 |
Rapid and adaptable measurement of protein thermal stability by differential scanning fluorimetry: updating a common biochemical laboratory experiment RJ Johnson, CJ Savas, Z Kartje, GC Hoops Journal of chemical education 91 (7), 1077-1080, 2014 | 45 | 2014 |
A ribonuclease zymogen activated by the NS3 protease of the hepatitis C virus RJ Johnson, SR Lin, RT Raines The FEBS journal 273 (23), 5457-5465, 2006 | 39 | 2006 |
Large scale structural rearrangement of a serine hydrolase from Francisella tularensis facilitates catalysis EV Filippova, LA Weston, ML Kuhn, B Geissler, AM Gehring, N Armoush, ... Journal of Biological Chemistry 288 (15), 10522-10535, 2013 | 36 | 2013 |
The structural basis for the narrow substrate specificity of an acetyl esterase from Thermotoga maritima MK Hedge, AM Gehring, CT Adkins, LA Weston, LD Lavis, RJ Johnson Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1824 (9), 1024-1030, 2012 | 36 | 2012 |
Cytotoxic ribonuclease variants RT Raines, GN Phillips, RJ Johnson, JG McCoy US Patent 7,655,757, 2010 | 30 | 2010 |
A sensitive and robust enzyme kinetic experiment using microplates and fluorogenic ester substrates RJ Johnson, GC Hoops, CJ Savas, Z Kartje, LD Lavis Journal of chemical education 92 (2), 385-388, 2015 | 26 | 2015 |
Does prolonged combined androgen blockade have survival benefits over short-term combined androgen blockade therapy? MF Sarosdy, PF Schellhammer, R Johnson, K Carroll, G Kolvenbag Urology 55 (3), 391-395, 2000 | 24 | 2000 |
Distinct Substrate Selectivity of a Metabolic Hydrolase from Mycobacterium tuberculosis JK Lukowski, CP Savas, AM Gehring, MG McKary, CT Adkins, LD Lavis, ... Biochemistry 53 (47), 7386-7395, 2014 | 23 | 2014 |
Decoupled roles for the atypical, bifurcated binding pocket of the ybfF hydrolase EE Ellis, CT Adkins, NM Galovska, LD Lavis, RJ Johnson ChemBioChem 14 (9), 1134-1144, 2013 | 23 | 2013 |
Intraspecies regulation of ribonucleolytic activity RJ Johnson, LD Lavis, RT Raines Biochemistry 46 (45), 13131-13140, 2007 | 23 | 2007 |
Structural basis for the strict substrate selectivity of the mycobacterial hydrolase LipW MG McKary, J Abendroth, TE Edwards, RJ Johnson Biochemistry 55 (51), 7099-7111, 2016 | 22 | 2016 |
Fatty Liver Subgroup of Look AHEAD Research Group Higher dietary fructose is associated with impaired hepatic adenosine triphosphate homeostasis in obese individuals with type … MF Abdelmalek, M Lazo, A Horska, S Bonekamp, EW Lipkin, ... Hepatology 56 (3), 952-960, 2012 | 16 | 2012 |
Measuring the global substrate specificity of mycobacterial serine hydrolases using a library of fluorogenic ester substrates B Bassett, B Waibel, A White, H Hansen, D Stephens, A Koelper, ... ACS infectious diseases 4 (6), 904-911, 2018 | 15 | 2018 |
Structure-guided microbial targeting of antistaphylococcal prodrugs JJ Miller, IT Shah, J Hatten, Y Barekatain, EA Mueller, AM Moustafa, ... Elife 10, e66657, 2021 | 14 | 2021 |
Ester-prodrugs of ethambutol control its antibacterial activity and provide rapid screening for mycobacterial hydrolase activity EM Larsen, DC Stephens, NH Clarke, RJ Johnson Bioorganic & medicinal chemistry letters 27 (19), 4544-4547, 2017 | 13 | 2017 |