| FinnGen provides genetic insights from a well-phenotyped isolated population MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, KM Donner, ... Nature 613 (7944), 508-518, 2023 | 1110 | 2023 |
| Diagnostic utility of exome sequencing for kidney disease EE Groopman, M Marasa, S Cameron-Christie, S Petrovski, VS Aggarwal, ... New England Journal of Medicine 380 (2), 142-151, 2019 | 628 | 2019 |
| Drug development in the era of precision medicine SA Dugger, A Platt, DB Goldstein Nature reviews Drug discovery 17 (3), 183-196, 2018 | 428 | 2018 |
| FinnGen: Unique genetic insights from combining isolated population and national health register data MI Kurki, J Karjalainen, P Palta, TP Sipilä, K Kristiansson, K Donner, ... medrxiv, 2022.03. 03.22271360, 2022 | 397 | 2022 |
| Rare variant contribution to human disease in 281,104 UK Biobank exomes Q Wang, RS Dhindsa, K Carss, AR Harper, A Nag, I Tachmazidou, ... Nature 597 (7877), 527-532, 2021 | 274 | 2021 |
| The yeast galactose genetic switch is mediated by the formation of a Gal4p–Gal80p–Gal3p complex A Platt, RJ Reece The EMBO journal, 1998 | 224 | 1998 |
| Identification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT … L Xia, L Wang, AS Chung, SS Ivanov, MY Ling, AM Dragoi, A Platt, ... Journal of Biological Chemistry 277 (34), 30716-30723, 2002 | 171 | 2002 |
| Nitrogen metabolite signalling involves the C‐terminus and the GATA domain of the Aspergillus transcription factor AREA and the 3′ untranslated region of its mRNA. A Platt, T Langdon, HN Arst Jr, D Kirk, D Tollervey, JM Sanchez, ... The EMBO journal 15 (11), 2791-2801, 1996 | 166 | 1996 |
| Biochemical markers of ongoing joint damage in rheumatoid arthritis-current and future applications, limitations and opportunities MA Karsdal, T Woodworth, K Henriksen, WP Maksymowych, H Genant, ... Arthritis research & therapy 13, 1-20, 2011 | 144 | 2011 |
| A distinct subset of chemokines dominates the mucosal chemokine response in inflammatory bowel disease J Puleston, M Cooper, S Murch, K Bid, S Makh, P Ashwood, AH Bingham, ... Alimentary pharmacology & therapeutics 21 (2), 109-120, 2005 | 144 | 2005 |
| The insertion of two amino acids into a transcriptional inducer converts it into a galactokinase A Platt, HC Ross, S Hankin, RJ Reece Proceedings of the National Academy of Sciences 97 (7), 3154-3159, 2000 | 136 | 2000 |
| Human immature monocyte-derived dendritic cells express the G protein-coupled receptor GPR105 (KIAA0001, P2Y14) and increase intracellular calcium in response to its agonist … L Skelton, M Cooper, M Murphy, A Platt The Journal of Immunology 171 (4), 1941-1949, 2003 | 114 | 2003 |
| Nitrogen regulation in fungi MX Caddick, D Peters, A Platt Antonie Van Leeuwenhoek 65, 169-177, 1994 | 107 | 1994 |
| IL-6 receptor inhibition positively modulates bone balance in rheumatoid arthritis patients with an inadequate response to anti-tumor necrosis factor therapy: biochemical … MA Karsdal, G Schett, P Emery, O Harari, I Byrjalsen, A Kenwright, ... Seminars in arthritis and rheumatism 42 (2), 131-139, 2012 | 99 | 2012 |
| Effect of tocilizumab combined with methotrexate on circulating biomarkers of synovium, cartilage, and bone in the LITHE study AC Bay-Jensen, A Platt, I Byrjalsen, P Vergnoud, C Christiansen, ... Seminars in arthritis and rheumatism 43 (4), 470-478, 2014 | 98 | 2014 |
| c-Jun N-terminal kinase primes endothelial cells at atheroprone sites for apoptosis H Chaudhury, M Zakkar, J Boyle, S Cuhlmann, K Van Der Heiden, ... Arteriosclerosis, thrombosis, and vascular biology 30 (3), 546-553, 2010 | 81 | 2010 |
| Genetic regulation of the human plasma proteome in 54,306 UK Biobank participants BB Sun, J Chiou, M Traylor, C Benner, YH Hsu, TG Richardson, ... BioRxiv, 2022.06. 17.496443, 2022 | 76 | 2022 |
| IL-6 pathway-driven investigation of response to IL-6 receptor inhibition in rheumatoid arthritis J Wang, A Platt, R Upmanyu, S Germer, G Lei, C Rabe, R Benayed, ... BMJ open 3 (8), e003199, 2013 | 66 | 2013 |
| A retrospective analysis of RET translocation, gene copy number gain and expression in NSCLC patients treated with vandetanib in four randomized Phase III studies A Platt, J Morten, Q Ji, P Elvin, C Womack, X Su, E Donald, N Gray, ... BMC cancer 15, 1-10, 2015 | 65 | 2015 |
| Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors M Alam, RE Beevers, T Ceska, RJ Davenport, KM Dickson, M Fortunato, ... Bioorganic & medicinal chemistry letters 17 (12), 3463-3467, 2007 | 63 | 2007 |
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