| Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification S Ito, AC D’Alessio, OV Taranova, K Hong, LC Sowers, Y Zhang Nature 466 (7310), 1129-1133, 2010 | 2968 | 2010 |
| Endogenous bile acids are ligands for the nuclear receptor FXR/BAR H Wang, J Chen, K Hollister, LC Sowers, BM Forman Molecular cell 3 (5), 543-553, 1999 | 1873 | 1999 |
| Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2) V Valinluck, HH Tsai, DK Rogstad, A Burdzy, A Bird, LC Sowers Nucleic acids research 32 (14), 4100-4108, 2004 | 879 | 2004 |
| Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1 V Valinluck, LC Sowers Cancer research 67 (3), 946-950, 2007 | 649 | 2007 |
| Comparison between DNA melting thermodynamics and DNA polymerase fidelity. J Petruska, MF Goodman, MS Boosalis, LC Sowers, C Cheong, ... Proceedings of the National Academy of Sciences 85 (17), 6252-6256, 1988 | 448 | 1988 |
| Dynamics of mismatched base pairs in DNA CR Guest, RA Hochstrasser, LC Sowers, DP Millar Biochemistry 30 (13), 3271-3279, 1991 | 308 | 1991 |
| Base pairing and mutagenesis: observation of a protonated base pair between 2-aminopurine and cytosine in an oligonucleotide by proton NMR. LC Sowers, GV Fazakerley, R Eritja, BE Kaplan, MF Goodman Proceedings of the National Academy of Sciences 83 (15), 5434-5438, 1986 | 295 | 1986 |
| Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA. DI Feig, LC Sowers, LA Loeb Proceedings of the National Academy of Sciences 91 (14), 6609-6613, 1994 | 262 | 1994 |
| First Principles Calculation of pKa Values for 5-Substituted Uracils YH Jang, LC Sowers, T Çaǧin, WA Goddard The Journal of Physical Chemistry A 105 (1), 274-280, 2001 | 250 | 2001 |
| pKa Values of Guanine in Water: Density Functional Theory Calculations Combined with Poisson−Boltzmann Continuum−Solvation Model YH Jang, WA Goddard, KT Noyes, LC Sowers, S Hwang, DS Chung The Journal of Physical Chemistry B 107 (1), 344-357, 2003 | 243 | 2003 |
| The abasic site as a challenge to DNA polymerase: a nuclear magnetic resonance study of G, C and T opposite a model abasic site P Cuniasse, GV Fazakerley, W Guschlbauer, BE Kaplan, LC Sowers Journal of molecular biology 213 (2), 303-314, 1990 | 214 | 1990 |
| Mechanism of human methyl-directed DNA methyltransferase and the fidelity of cytosine methylation. SS Smith, BE Kaplan, LC Sowers, EM Newman Proceedings of the National Academy of Sciences 89 (10), 4744-4748, 1992 | 208 | 1992 |
| Comparison of nucleotide interactions in water, proteins, and vacuum: model for DNA polymerase fidelity. J Petruska, LC Sowers, MF Goodman Proceedings of the National Academy of Sciences 83 (6), 1559-1562, 1986 | 207 | 1986 |
| The nucleotide analog 2-aminopurine as a spectroscopic probe of nucleotide incorporation by the Klenow fragment of Escherichia coli polymerase I and bacteriophage T4 DNA polymerase MW Frey, LC Sowers, DP Millar, SJ Benkovic Biochemistry 34 (28), 9185-9192, 1995 | 203 | 1995 |
| A fluorescence-based assay for monitoring helicase activity. KD Raney, LC Sowers, DP Millar, SJ Benkovic Proceedings of the National Academy of Sciences 91 (14), 6644-6648, 1994 | 179 | 1994 |
| Inflammation-mediated cytosine damage: a mechanistic link between inflammation and the epigenetic alterations in human cancers V Valinluck, LC Sowers Cancer research 67 (12), 5583-5586, 2007 | 172 | 2007 |
| Metabolism and anti-human immunodeficiency virus-1 activity of 2-halo-2 ‘, 3 ‘-dideoxyadenosine derivatives. T Haertle, CJ Carrera, DB Wasson, LC Sowers, DD Richman, DA Carson Journal of Biological Chemistry 263 (12), 5870-5875, 1988 | 166 | 1988 |
| Molecular basis of cisplatin resistance in human carcinomas: model systems and patients. KJ Scanlon, M Kashani-Sabet, H Miyachi, LC Sowers, J Rossi Anticancer Research 9 (5), 1301-1312, 1989 | 150 | 1989 |
| Melting of a DNA helix terminus within the active site of a DNA polymerase RA Hochstrasser, TE Carver, LC Sowers, DP Millar Biochemistry 33 (39), 11971-11979, 1994 | 137 | 1994 |
| Base stacking and molecular polarizability: effect of a methyl group in the 5-position of pyrimidines LC Sowers, BR Shaw, WD Sedwick Biochemical and biophysical research communications 148 (2), 790-794, 1987 | 137 | 1987 |
