Protein kinase C and cancer: what we know and what we do not R Garg, LG Benedetti, MB Abera, H Wang, M Abba, MG Kazanietz Oncogene 33 (45), 5225-5237, 2014 | 328 | 2014 |
The role of the matricellular protein SPARC in the dynamic interaction between the tumor and the host OL Podhajcer, L Benedetti, MR Girotti, F Prada, E Salvatierra, AS Llera Cancer and Metastasis Reviews 27, 523-537, 2008 | 312 | 2008 |
Nanoscale subcellular architecture revealed by multicolor three-dimensional salvaged fluorescence imaging Y Zhang, LK Schroeder, MD Lessard, P Kidd, J Chung, Y Song, ... Nature methods 17 (2), 225-231, 2020 | 104 | 2020 |
SPARC promotes cathepsin B-mediated melanoma invasiveness through a collagen I/α2β1 integrin axis MR Girotti, M Fernández, JA López, E Camafeita, EA Fernández, JP Albar, ... Journal of investigative dermatology 131 (12), 2438-2447, 2011 | 94 | 2011 |
Immunogenomics of colorectal cancer response to checkpoint blockade: analysis of the KEYNOTE 177 trial and validation cohorts M Bortolomeazzi, MR Keddar, L Montorsi, A Acha-Sagredo, L Benedetti, ... Gastroenterology 161 (4), 1179-1193, 2021 | 84 | 2021 |
Synthetic lethal interaction between the tumour suppressor STAG2 and its paralog STAG1 L Benedetti, M Cereda, LA Monteverde, N Desai, FD Ciccarelli Oncotarget 8 (23), 37619, 2017 | 79 | 2017 |
SPARC endogenous level, rather than fibroblast-produced SPARC or stroma reorganization induced by SPARC, is responsible for melanoma cell growth F Prada, LG Benedetti, AI Bravo, MJ Alvarez, C Carbone, OL Podhajcer Journal of Investigative Dermatology 127 (11), 2618-2628, 2007 | 71 | 2007 |
SPARC downregulation attenuates the profibrogenic response of hepatic stellate cells induced by TGF-β1 and PDGF C Atorrasagasti, JB Aquino, L Hofman, L Alaniz, M Malvicini, M Garcia, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 300 (5 …, 2011 | 57 | 2011 |
Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells L Benedetti, JS Marvin, H Falahati, A Guillén-Samander, LL Looger, ... Elife 9, e63230, 2020 | 53 | 2020 |
Patients with genetically heterogeneous synchronous colorectal cancer carry rare damaging germline mutations in immune-related genes M Cereda, G Gambardella, L Benedetti, F Iannelli, D Patel, G Basso, ... Nature Communications 7 (1), 12072, 2016 | 52 | 2016 |
The inositol 5-phosphatase INPP5K participates in the fine control of ER organization R Dong, T Zhu, L Benedetti, S Gowrishankar, H Deng, Y Cai, X Wang, ... The Journal of cell biology 217 (10), 3577, 2018 | 47 | 2018 |
INaP selective inhibition reverts precocious inter- and motorneurons hyperexcitability in the Sod1-G93R zebrafish ALS model L Benedetti, A Ghilardi, E Rottoli, M De Maglie, L Prosperi, C Perego, ... Scientific reports 6 (1), 24515, 2016 | 41 | 2016 |
Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation L Barrio-Real, LG Benedetti, N Engel, Y Tu, S Cho, S Sukumar, ... Breast Cancer Research 16, 1-13, 2014 | 41 | 2014 |
Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma TP Mourikis, L Benedetti, E Foxall, D Temelkovski, J Nulsen, J Perner, ... Nature Communications 10 (1), 3101, 2019 | 40 | 2019 |
CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function L Lataniotis, A Albrecht, FO Kok, CAL Monfries, L Benedetti, ND Lawson, ... Scientific reports 7 (1), 8585, 2017 | 37 | 2017 |
A tumor-stroma targeted oncolytic adenovirus replicated in human ovary cancer samples and inhibited growth of disseminated solid tumors in mice MV Lopez, AA Rivera, DL Viale, L Benedetti, N Cuneo, KJ Kimball, ... Molecular Therapy 20 (12), 2222-2233, 2012 | 28 | 2012 |
Predictive outcomes for HER2-enriched cancer using growth and metastasis signatures driven by SPARC LN Güttlein, LG Benedetti, C Fresno, RG Spallanzani, SF Mansilla, ... Molecular Cancer Research 15 (3), 304-316, 2017 | 25 | 2017 |
Matricellular proteins and inflammatory cells: a task force to promote or defeat cancer? AS Llera, MR Girotti, LG Benedetti, OL Podhajcer Cytokine & growth factor reviews 21 (1), 67-76, 2010 | 25 | 2010 |
Hippocampal SPARC regulates depression‐related behavior M Campolongo, L Benedetti, OL Podhajcer, F Pitossi, AM Depino Genes, Brain and Behavior 11 (8), 966-976, 2012 | 22 | 2012 |
YAP1 nuclear efflux and transcriptional reprograming follow membrane diminution upon VSV-G-induced cell fusion D Feliciano, CM Ott, I Espinosa-Medina, AV Weigel, L Benedetti, ... Nature Communications 12 (1), 4502, 2021 | 7 | 2021 |