Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II D Baillat, MA Hakimi, AM Näär, A Shilatifard, N Cooch, R Shiekhattar Cell 123 (2), 265-276, 2005 | 560 | 2005 |
Reinforcement of silencing at transposons and highly repeated sequences requires the concerted action of two distinct RNA polymerases IV in Arabidopsis D Pontier, G Yahubyan, D Vega, A Bulski, J Saez-Vasquez, MA Hakimi, ... Genes & development 19 (17), 2030-2040, 2005 | 462 | 2005 |
Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components M El-Shami, D Pontier, S Lahmy, L Braun, C Picart, D Vega, MA Hakimi, ... Genes & development 21 (20), 2539-2544, 2007 | 377 | 2007 |
A core–BRAF35 complex containing histone deacetylase mediates repression of neuronal-specific genes MA Hakimi, DA Bochar, J Chenoweth, WS Lane, G Mandel, R Shiekhattar Proceedings of the National Academy of Sciences 99 (11), 7420-7425, 2002 | 365 | 2002 |
A chromatin remodelling complex that loads cohesin onto human chromosomes MA Hakimi, DA Bochar, JA Schmiesing, Y Dong, OG Barak, DW Speicher, ... Nature 418 (6901), 994-998, 2002 | 360 | 2002 |
Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein J Azevedo, D Garcia, D Pontier, S Ohnesorge, A Yu, S Garcia, L Braun, ... Genes & development 24 (9), 904-915, 2010 | 350 | 2010 |
Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair Y Dong, MA Hakimi, X Chen, E Kumaraswamy, NS Cooch, AK Godwin, ... Molecular cell 12 (5), 1087-1099, 2003 | 344 | 2003 |
Toxoplasma Effectors Targeting Host Signaling and Transcription MA Hakimi, P Olias, LD Sibley Clinical microbiology reviews 30 (3), 615-645, 2017 | 317 | 2017 |
Functional interplay between histone demethylase and deacetylase enzymes MG Lee, C Wynder, DA Bochar, MA Hakimi, N Cooch, R Shiekhattar Molecular and cellular biology 26 (17), 6395-6402, 2006 | 313 | 2006 |
A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation L Braun, MP Brenier-Pinchart, M Yogavel, A Curt-Varesano, ... Journal of Experimental Medicine 210 (10), 2071-2086, 2013 | 287 | 2013 |
Host cell subversion by Toxoplasma GRA16, an exported dense granule protein that targets the host cell nucleus and alters gene expression A Bougdour, E Durandau, MP Brenier-Pinchart, P Ortet, M Barakat, ... Cell host & microbe 13 (4), 489-500, 2013 | 262 | 2013 |
The Toxoplasma dense granule proteins GRA17 and GRA23 mediate the movement of small molecules between the host and the parasitophorous vacuole DA Gold, AD Kaplan, A Lis, GCL Bett, EE Rosowski, KM Cirelli, ... Cell host & microbe 17 (5), 642-652, 2015 | 248 | 2015 |
A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes MA Hakimi, Y Dong, WS Lane, DW Speicher, R Shiekhattar Journal of Biological Chemistry 278 (9), 7234-7239, 2003 | 241 | 2003 |
Histone-modifying complexes regulate gene expression pertinent to the differentiation of the protozoan parasite Toxoplasma gondii N Saksouk, MM Bhatti, S Kieffer, AT Smith, K Musset, J Garin, ... Molecular and cellular biology, 2005 | 224 | 2005 |
Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ–mediated host defenses G Gay, L Braun, MP Brenier-Pinchart, J Vollaire, V Josserand, RL Bertini, ... Journal of Experimental Medicine 213 (9), 1779-1798, 2016 | 200 | 2016 |
Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites A Bougdour, D Maubon, P Baldacci, P Ortet, O Bastien, A Bouillon, ... Journal of Experimental Medicine 206 (4), 953-966, 2009 | 197 | 2009 |
A complex small RNA repertoire is generated by a plant/fungal-like machinery and effected by a metazoan-like Argonaute in the single-cell human parasite Toxoplasma gondii L Braun, D Cannella, P Ortet, M Barakat, CF Sautel, S Kieffer, J Garin, ... PLoS pathogens 6 (5), e1000920, 2010 | 123 | 2010 |
Characterization of Arabidopsisplastid sigma-like transcription factors SIG1, SIG2 and SIG3 I Privat, MA Hakimi, L Buhot, JJ Favory, S Lerbs-Mache Plant molecular biology 51, 385-399, 2003 | 120 | 2003 |
The aspartyl protease TgASP5 mediates the export of the Toxoplasma GRA16 and GRA24 effectors into host cells A Curt‐Varesano, L Braun, C Ranquet, MA Hakimi, A Bougdour Cellular microbiology 18 (2), 151-167, 2016 | 115 | 2016 |
Structure of prolyl-tRNA synthetase-halofuginone complex provides basis for development of drugs against malaria and toxoplasmosis V Jain, M Yogavel, Y Oshima, H Kikuchi, B Touquet, MA Hakimi, ... Structure 23 (5), 819-829, 2015 | 111 | 2015 |