Mutation-independent rhodopsin gene therapy by knockdown and replacement with a single AAV vector AV Cideciyan, R Sudharsan, VL Dufour, MT Massengill, S Iwabe, ... Proceedings of the National Academy of Sciences 115 (36), E8547-E8556, 2018 | 136 | 2018 |
Deoxycholate interacts with IpaD of Shigella flexneri in inducing the recruitment of IpaB to the type III secretion apparatus needle tip KF Stensrud, PR Adam, CD La Mar, AJ Olive, GH Lushington, ... Journal of Biological Chemistry 283 (27), 18646-18654, 2008 | 120 | 2008 |
Involvement of innate immune system in late stages of inherited photoreceptor degeneration R Sudharsan, DP Beiting, GD Aguirre, WA Beltran Scientific reports 7 (1), 17897, 2017 | 34 | 2017 |
The SUMO ligase PIAS1 regulates UV-induced apoptosis by recruiting Daxx to SUMOylated foci R Sudharsan, Y Azuma Journal of cell science 125 (23), 5819-5829, 2012 | 24 | 2012 |
Genome-wide association study and whole-genome sequencing identify a deletion in LRIT3 associated with canine congenital stationary night blindness RG Das, D Becker, V Jagannathan, O Goldstein, E Santana, K Carlin, ... Scientific reports 9 (1), 14166, 2019 | 23 | 2019 |
Gene therapy reforms photoreceptor structure and restores vision in NPHP5-associated Leber congenital amaurosis GD Aguirre, AV Cideciyan, VL Dufour, A Ripolles-García, R Sudharsan, ... Molecular Therapy 29 (8), 2456-2468, 2021 | 21 | 2021 |
Exclusion of the unfolded protein response in light-induced retinal degeneration in the canine T4R RHO model of autosomal dominant retinitis pigmentosa S Marsili, S Genini, R Sudharsan, J Gingrich, GD Aguirre, WA Beltran PLoS One 10 (2), e0115723, 2015 | 20 | 2015 |
Progress in gene therapy for rhodopsin autosomal dominant retinitis pigmentosa R Sudharsan, WA Beltran Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 113-118, 2019 | 18 | 2019 |
Comparative localization of cystathionine beta synthases and cystathionine gamma lyase in canine, non-human primate and human retina A Badiei, R Sudharsan, E Santana, JL Dunaief, GD Aguirre Experimental eye research 181, 72-84, 2019 | 16 | 2019 |
Acute and protracted cell death in light-induced retinal degeneration in the canine model of rhodopsin autosomal dominant retinitis pigmentosa R Sudharsan, KM Simone, NP Anderson, GD Aguirre, WA Beltran Investigative Ophthalmology & Visual Science 58 (1), 270-281, 2017 | 16 | 2017 |
Short prolactin isoforms are expressed in photoreceptors of canine retinas undergoing retinal degeneration R Sudharsan, L Murgiano, HY Tang, TW Olsen, VRM Chavali, GD Aguirre, ... Scientific reports 11 (1), 460, 2021 | 4 | 2021 |
Photoreceptor outer segment isolation from a single canine retina for RPE phagocytosis assay R Sudharsan, MH Elliott, N Dolgova, GD Aguirre, WA Beltran Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 593-601, 2018 | 3 | 2018 |
Assessment of AAV-mediated RHO augmentation in the canine T4R RHO model of autosomal dominant retinitis pigmentosa S Iwabe, S Genini, R Sudharsan, AS Lewin, BP Rossmiller, ... Investigative Ophthalmology & Visual Science 55 (13), 3316-3316, 2014 | 2 | 2014 |
Photochemical restoration of light sensitivity in the degenerated canine retina S Nikonov, N Dolgova, R Sudharsan, I Tochitsky, S Iwabe, JM Guzman, ... Pharmaceutics 14 (12), 2711, 2022 | 1 | 2022 |
Author correction: involvement of innate immune system in late stages of inherited photoreceptor degeneration R Sudharsan, DP Beiting, GD Aguirre, WA Beltran Scientific Reports 8, 2018 | 1 | 2018 |
An optimized workflow for transcriptomic analysis from archival paraformaldehyde-fixed retinal tissues collected by laser capture microdissection K Takahashi, WA Beltran, R Sudharsan Experimental Eye Research, 109989, 2024 | | 2024 |
Mapping protein distribution in the canine photoreceptor sensory cilium and calyceal processes by ultrastructure expansion microscopy K Takahashi, R Sudharsan, WA Beltran bioRxiv, 2024.06. 27.600953, 2024 | | 2024 |
Identification of photoreceptor-specific promoters for gene therapy at advanced stages of retinal degeneration R Sudharsan, L Murgiano, A Ahuja, Y Sato, JC Kwok, M Sedorovitz, ... Investigative Ophthalmology & Visual Science 65 (7), 5315-5315, 2024 | | 2024 |
Ultrastructure expansion microscopy for characterization of the canine photoreceptor sensory cilium K Takahashi, R Sudharsan, WA Beltran Investigative Ophthalmology & Visual Science 65 (7), 5578-5578, 2024 | | 2024 |
Impact of subretinal AAV delivery on the transcriptomic inflammatory profile of the degenerating retina R Sudharsan, JC Kwok, GD Aguirre, WA Beltran Investigative Ophthalmology & Visual Science 64 (8), 3023-3023, 2023 | | 2023 |