Metabolism and metabolites of polychlorinated biphenyls FA Grimm, D Hu, I Kania-Korwel, HJ Lehmler, G Ludewig, KC Hornbuckle, ... Critical reviews in toxicology 45 (3), 245-272, 2015 | 422 | 2015 |
High-content assay multiplexing for toxicity screening in induced pluripotent stem cell-derived cardiomyocytes and hepatocytes FA Grimm, Y Iwata, O Sirenko, M Bittner, I Rusyn Assay and drug development technologies 13 (9), 529-546, 2015 | 125 | 2015 |
Sulfated metabolites of polychlorinated biphenyls are high-affinity ligands for the thyroid hormone transport protein transthyretin FA Grimm, HJ Lehmler, X He, LW Robertson, MW Duffel Environmental health perspectives 121 (6), 657-662, 2013 | 110 | 2013 |
ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models SW Marvel, K To, FA Grimm, FA Wright, I Rusyn, DM Reif BMC bioinformatics 19, 1-7, 2018 | 108 | 2018 |
A chemical–biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives FA Grimm, Y Iwata, O Sirenko, GA Chappell, FA Wright, DM Reif, ... Green chemistry 18 (16), 4407-4419, 2016 | 90 | 2016 |
In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model O Sirenko, FA Grimm, KR Ryan, Y Iwata, WA Chiu, F Parham, JA Wignall, ... Toxicology and applied pharmacology 322, 60-74, 2017 | 82 | 2017 |
Technology transfer of the microphysiological systems: a case study of the human proximal tubule tissue chip C Sakolish, EJ Weber, EJ Kelly, J Himmelfarb, R Mouneimne, FA Grimm, ... Scientific reports 8 (1), 14882, 2018 | 78 | 2018 |
Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes SD Burnett, AD Blanchette, FA Grimm, JS House, DM Reif, FA Wright, ... Toxicology and applied pharmacology 381, 114711, 2019 | 57 | 2019 |
A pipeline for high-throughput concentration response modeling of gene expression for toxicogenomics JS House, FA Grimm, DD Jima, YH Zhou, I Rusyn, FA Wright Frontiers in genetics 8, 168, 2017 | 56 | 2017 |
Tissue distribution, metabolism, and excretion of 3, 3′-dichloro-4′-sulfooxy-biphenyl in the rat FA Grimm, X He, LM Teesch, HJ Lehmler, LW Robertson, MW Duffel Environmental science & technology 49 (13), 8087-8095, 2015 | 48 | 2015 |
A human population-based organotypic in vitro model for cardiotoxicity screening FA Grimm, A Blanchette, JS House, K Ferguson, NH Hsieh, C Dalaijamts, ... Altex 35 (4), 441, 2018 | 46 | 2018 |
Identification of a sulfate metabolite of PCB 11 in human serum FA Grimm, HJ Lehmler, WX Koh, J DeWall, LM Teesch, KC Hornbuckle, ... Environment international 98, 120-128, 2017 | 43 | 2017 |
Revealing adverse outcome pathways from public high-throughput screening data to evaluate new toxicants by a knowledge-based deep neural network approach HL Ciallella, DP Russo, LM Aleksunes, FA Grimm, H Zhu Environmental science & technology 55 (15), 10875-10887, 2021 | 35 | 2021 |
Predictive modeling of estrogen receptor agonism, antagonism, and binding activities using machine-and deep-learning approaches HL Ciallella, DP Russo, LM Aleksunes, FA Grimm, H Zhu Laboratory investigation 101 (4), 490-502, 2021 | 35 | 2021 |
High-content assay multiplexing for vascular toxicity screening in induced pluripotent stem cell-derived endothelial cells and human umbilical vein endothelial cells Y Iwata, WD Klaren, CS Lebakken, FA Grimm, I Rusyn Assay and drug development technologies 15 (6), 267-279, 2017 | 34 | 2017 |
Cardiovascular effects of polychlorinated biphenyls and their major metabolites FA Grimm, WD Klaren, X Li, HJ Lehmler, M Karmakar, LW Robertson, ... Environmental health perspectives 128 (7), 077008, 2020 | 31 | 2020 |
Thorough QT/QTc in a Dish: An In Vitro Human Model That Accurately Predicts Clinical Concentration‐QTc Relationships AD Blanchette, FA Grimm, C Dalaijamts, NH Hsieh, K Ferguson, YS Luo, ... Clinical Pharmacology & Therapeutics 105 (5), 1175-1186, 2019 | 31 | 2019 |
Grouping of UVCB substances with new approach methodologies (NAMs) data JS House, FA Grimm, WD Klaren, A Dalzell, S Kuchi, SD Zhang, K Lenz, ... Altex 38 (1), 123, 2021 | 29 | 2021 |
A Bayesian Method for Population-wide Cardiotoxicity Hazard and Risk Characterization Using an In Vitro Human Model AD Blanchette, SD Burnett, FA Grimm, I Rusyn, WA Chiu Toxicological sciences 178 (2), 391-403, 2020 | 26 | 2020 |
Grouping of petroleum substances as example UVCBs by ion mobility-mass spectrometry to enable chemical composition-based read-across FA Grimm, WK Russell, YS Luo, Y Iwata, WA Chiu, T Roy, PJ Boogaard, ... Environmental science & technology 51 (12), 7197-7207, 2017 | 26 | 2017 |