Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1, 2, 4-triazoline-3-thiones AA El-Emam, AMS Al-Tamimi, MA Al-Omar, KA Alrashood, EE Habib European journal of medicinal chemistry 68, 96-102, 2013 | 102 | 2013 |
Carbonic anhydrase inhibition and the management of glaucoma: a literature and patent review 2013-2019 CT Supuran, ASA Altamimi, F Carta Expert opinion on therapeutic patents 29 (10), 781-792, 2019 | 63 | 2019 |
Discovery of novel nonsteroidal anti-inflammatory drugs and carbonic anhydrase inhibitors hybrids (NSAIDs–CAIs) for the management of rheumatoid arthritis O Akgul, L Di Cesare Mannelli, D Vullo, A Angeli, C Ghelardini, ... Journal of Medicinal Chemistry 61 (11), 4961-4977, 2018 | 53 | 2018 |
Quinazoline–sulfonamides with potent inhibitory activity against the α-carbonic anhydrase from Vibrio cholerae AM Alafeefy, M Ceruso, AMS Al-Tamimi, S Del Prete, C Capasso, ... Bioorganic & Medicinal Chemistry 22 (19), 5133-5140, 2014 | 50 | 2014 |
Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides … AM Alafeefy, HA Abdel-Aziz, D Vullo, AMS Al-Tamimi, NA Al-Jaber, ... Bioorganic & medicinal chemistry 22 (1), 141-147, 2014 | 47 | 2014 |
Inhibition studies of quinazoline-sulfonamide derivatives against the γ-CA (PgiCA) from the pathogenic bacterium, Porphyromonas gingivalis AM Alafeefy, M Ceruso, AMS Al-Tamimi, SD Prete, CT Supuran, ... Journal of Enzyme Inhibition and Medicinal Chemistry 30 (4), 592-596, 2015 | 46 | 2015 |
Structural and spectroscopic characterization of a novel potential chemotherapeutic agent 3-(1-adamantyl)-1-{[4-(2-methoxyphenyl) piperazin-1-yl] methyl}-4-methyl-1H-1, 2, 4 … AA El-Emam, AMS Al-Tamimi, KA Al-Rashood, HN Misra, V Narayan, ... Journal of Molecular Structure 1022, 49-60, 2012 | 42 | 2012 |
A review on epidermal growth factor receptor's role in breast and non-small cell lung cancer V Subramaniyan, S Fuloria, G Gupta, DH Kumar, M Sekar, KV Sathasivam, ... Chemico-biological interactions 351, 109735, 2022 | 41 | 2022 |
Development of certain new 2-substituted-quinazolin-4-yl-aminobenzenesulfonamide as potential antitumor agents AM Alafeefy, R Ahmad, M Abdulla, WM Eldehna, AMS Al-Tamimi, ... European Journal of Medicinal Chemistry 109, 247-253, 2016 | 41 | 2016 |
Inhibition of human carbonic anhydrase isozymes I, II, IX and XII with a new series of sulfonamides incorporating aroylhydrazone-,[1, 2, 4] triazolo [3, 4-b][1, 3, 4 … AM Alafeefy, HA Abdel-Aziz, D Vullo, AMS Al-Tamimi, AS Awaad, ... Journal of Enzyme Inhibition and Medicinal Chemistry 30 (1), 52-56, 2015 | 41 | 2015 |
Discovery of new organoselenium compounds as antileishmanial agents AMS Al-Tamimi, M Etxebeste-Mitxeltorena, C Sanmartin, A Jimenez-Ruiz, ... Bioorganic Chemistry 86, 339-345, 2019 | 35 | 2019 |
Coumarins and other fused bicyclic heterocycles with selective tumor-associated carbonic anhydrase isoforms inhibitory activity M Bozdag, AM Alafeefy, AM Altamimi, D Vullo, F Carta, CT Supuran Bioorganic & Medicinal Chemistry 25 (2), 677-683, 2017 | 35 | 2017 |
Carbonic anhydrase inhibitors based on sorafenib scaffold: design, synthesis, crystallographic investigation and effects on primary breast cancer cells M Bozdag, M Ferraroni, C Ward, F Carta, S Bua, A Angeli, SP Langdon, ... European Journal of Medicinal Chemistry 182, 111600, 2019 | 29 | 2019 |
Synthesis and Antimicrobial Activity of N′-Heteroarylidene-1-adamantylcarbohydrazides and (±)-2-(1-Adamantyl)-4-acetyl-5-[5-(4-substituted phenyl-3-isoxazolyl … AA El-Emam, KA Alrashood, MA Al-Omar, AMS Al-Tamimi Molecules 17 (3), 3475-3483, 2012 | 29 | 2012 |
Cationic solid lipid nanoparticles of resveratrol for hepatocellular carcinoma treatment: systematic optimization, in vitro characterization and preclinical investigation M Rahman, WH Almalki, O Afzal, AS Alfawaz Altamimi, I Kazmi, ... International Journal of Nanomedicine, 9283-9299, 2020 | 28 | 2020 |
3-(1-Adamantyl)-1-{[4-(2-methoxyphenyl) piperazin-1-yl] methyl}-4-methyl-1H-1, 2, 4-triazole-5 (4H)-thione A Al-Tamimi, A Bari, MA Al-Omar, KA Alrashood, AA El-Emam Acta Crystallographica Section E: Structure Reports Online 66 (7), o1756-o1756, 2010 | 28 | 2010 |
Sodium alginate based drug delivery in management of breast cancer MAJ Shaikh, KS Alharbi, WH Almalki, SS Imam, M Albratty, AM Meraya, ... Carbohydrate polymers 292, 119689, 2022 | 26 | 2022 |
Drug delivery challenges and current progress in nanocarrier-based ocular therapeutic system MH Akhter, I Ahmad, MY Alshahrani, AI Al-Harbi, H Khalilullah, O Afzal, ... Gels 8 (2), 82, 2022 | 24 | 2022 |
Investigation of potential anti-malarial lead candidate 2-(4-fluorobenzylthio)-5-(5-bromothiophen-2-yl)-1, 3, 4-oxadiazole: Insights from crystal structure, DFT, QTAIM and … LH Al-Wahaibi, NS Kumar, AA El-Emam, NS Venkataramanan, ... Journal of Molecular Structure 1175, 230-240, 2019 | 24 | 2019 |
Neuroprotective role of chrysin‐loaded poly (lactic‐co‐glycolic acid) nanoparticle against kindling‐induced epilepsy through Nrf2/ARE/HO‐1 pathway Y Zhang, J Zhao, O Afzal, I Kazmi, FA Al‐Abbasi, ASA Altamimi, Z Yang Journal of Biochemical and Molecular Toxicology 35 (2), e22634, 2021 | 23 | 2021 |