关注
Yuancheng (Ryan) Lu
Yuancheng (Ryan) Lu
其他姓名吕垣澄
LSRF and AFAR Postdoctoral Fellow, MIT/Whitehead
在 wi.mit.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Reprogramming to recover youthful epigenetic information and restore vision
Y Lu, B Brommer, X Tian, A Krishnan, M Meer, C Wang, DL Vera, Q Zeng, ...
Nature 588 (7836), 124-129, 2020
5592020
Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging
A Das, GX Huang, MS Bonkowski, A Longchamp, C Li, MB Schultz, ...
Cell 173 (1), 74-89. e20, 2018
4022018
Loss of epigenetic information as a cause of mammalian aging
JH Yang, M Hayano, PT Griffin, JA Amorim, MS Bonkowski, ...
Cell 186 (2), 305-326. e27, 2023
2702023
Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging
A Das, GX Huang, MS Bonkowski, A Longchamp, C Li, MB Schultz, ...
Cell 176 (4), 944-945, 2019
422019
Reversal of ageing-and injury-induced vision loss by Tet-dependent epigenetic reprogramming
Y Lu, A Krishnan, B Brommer, X Tian, M Meer, DL Vera, C Wang, Q Zeng, ...
BioRxiv, 710210, 2019
272019
Gene therapy-mediated partial reprogramming extends lifespan and reverses age-related changes in aged mice
CC Macip, R Hasan, V Hoznek, J Kim, YR Lu, LE Metzger IV, S Sethna, ...
Cellular Reprogramming 26 (1), 24-32, 2024
222024
Molecular and cellular characterization of SIRT1 allosteric activators
MB Schultz, C Rinaldi, Y Lu, JA Amorim, DA Sinclair
Protein Acetylation: Methods and Protocols, 133-149, 2019
182019
Spateo: multidimensional spatiotemporal modeling of single-cell spatial transcriptomics
X Qiu, DY Zhu, J Yao, Z Jing, L Zuo, M Wang, KH Min, H Pan, S Wang, ...
BioRxiv, 2022.12. 07.519417, 2022
172022
The information theory of aging
YR Lu, X Tian, DA Sinclair
Nature aging 3 (12), 1486-1499, 2023
122023
Assays for NAD+-Dependent Reactions and NAD+ Metabolites
MB Schultz, Y Lu, N Braidy, DA Sinclair
ADP-ribosylation and NAD+ Utilizing Enzymes: Methods and Protocols, 77-90, 2018
82018
Sustained vision recovery by OSK gene therapy in a mouse model of glaucoma
MM Karg, YR Lu, N Refaian, J Cameron, E Hoffmann, C Hoppe, ...
Cellular Reprogramming 25 (6), 288-299, 2023
52023
Epigenetic reprogramming-A novel gene therapy that restores vision loss in a nonhuman primate model of NAION
B Ksander, M Shah, D Krasniqi, MS Gregory-Ksander, ...
Investigative Ophthalmology & Visual Science 64 (8), 474-474, 2023
52023
动物隐花色素研究进展
吕垣澄, 吴晓晖
遗传 36 (9), 864-870, 2014
32014
The Role of Epigenetics in Accelerated Aging: A Reconsideration of Later-Life Visual Loss After Early Optic Neuropathy
JF Rizzo 3rd, MP Shah, D Krasniqi, YR Lu, DA Sinclair, BR Ksander
Journal of neuro-ophthalmology: the official journal of the North American …, 2023
2*2023
Loss of epigenetic information as a cause of mammalian aging
JH Yang, M Hayano, P Griffin, JA Amorim, MS Bonkowski, JK Apostolides, ...
22021
Reversal of aging-induced and glaucoma-induced vision loss by in vivo epigenetic reprogramming
B Ksander, Y Lu, A Krishnan, B Brommer, X Tian, M Meer, D Vera, ...
Investigative Ophthalmology & Visual Science 61 (7), 2364-2364, 2020
22020
In vivo cellular reprogramming for tissue regeneration and age reversal
Y Lu, D Yu, M Bonkowski, M Schultz, X Tian, J Yang, Z He, D Sinclair
Innovation in Aging 2 (Suppl 1), 883, 2018
22018
Non-human primate laser-induced NAION model for assessing neuro-rejuvenating gene therapies
M Shah, D Krasniqi, MS Gregory-Ksander, S Rosenzweig-Lipson, ...
Investigative Ophthalmology & Visual Science 64 (8), 5223-5223, 2023
12023
Mutant reverse tetracycline transactivators for expression of genes
DA Sinclair, Y Lu, NJ DAVIDSOHN
12021
In vivo epigenetic reprogramming reverses the age-induced morphological decline of retinal pigment epithelial cells
M Karg, Y Lu, E Hoffmann, H Philipose, D Sinclair, B Ksander, ...
Investigative Ophthalmology & Visual Science 62 (8), 3283-3283, 2021
12021
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