| Structural insights into the YAP and TEAD complex Z Li, B Zhao, P Wang, F Chen, Z Dong, H Yang, KL Guan, Y Xu Genes & development 24 (3), 235-240, 2010 | 413 | 2010 |
| Born to run: control of transcription elongation by RNA polymerase II FX Chen, ER Smith, A Shilatifard Nature reviews Molecular cell biology 19 (7), 464-478, 2018 | 388 | 2018 |
| PAF1, a molecular regulator of promoter-proximal pausing by RNA polymerase II FX Chen, AR Woodfin, A Gardini, RA Rickels, SA Marshall, ER Smith, ... Cell 162 (5), 1003-1015, 2015 | 254 | 2015 |
| Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase H Zheng, Y Qi, S Hu, X Cao, C Xu, Z Yin, X Chen, Y Li, W Liu, J Li, J Wang, ... Science 370 (6520), eabb5872, 2020 | 137 | 2020 |
| PAF1 regulation of promoter-proximal pause release via enhancer activation FX Chen, P Xie, CK Collings, K Cao, Y Aoi, SA Marshall, EJ Rendleman, ... Science 357 (6357), 1294-1298, 2017 | 134 | 2017 |
| NELF regulates a promoter-proximal step distinct from RNA Pol II pause-release Y Aoi, ER Smith, AP Shah, EJ Rendleman, SA Marshall, AR Woodfin, ... Molecular cell 78 (2), 261-274. e5, 2020 | 129 | 2020 |
| Stably paused genes revealed through inhibition of transcription initiation by the TFIIH inhibitor triptolide F Chen, X Gao, A Shilatifard Genes & development 29 (1), 39-47, 2015 | 129 | 2015 |
| Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin … J Cheng, Y Yang, J Fang, J Xiao, T Zhu, F Chen, P Wang, Z Li, H Yang, ... Journal of Biological Chemistry 288 (2), 1329-1339, 2013 | 128 | 2013 |
| LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation R Fang, F Chen, Z Dong, D Hu, AJ Barbera, EA Clark, J Fang, Y Yang, ... Molecular cell 49 (3), 558-570, 2013 | 100 | 2013 |
| Histone H3K4 methylation-dependent and-independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation CC Sze, K Cao, CK Collings, SA Marshall, EJ Rendleman, PA Ozark, ... Genes & development 31 (17), 1732-1737, 2017 | 91 | 2017 |
| ID1 mediates escape from TGFβ tumor suppression in pancreatic cancer YH Huang, J Hu, F Chen, N Lecomte, H Basnet, CJ David, MD Witkin, ... Cancer discovery 10 (1), 142-157, 2020 | 69 | 2020 |
| SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape S Hu, L Peng, C Xu, Z Wang, A Song, FX Chen Molecular Cell 81 (21), 4425-4439. e6, 2021 | 63 | 2021 |
| Structural insight into substrate recognition by histone demethylase LSD2/KDM1b F Chen, H Yang, Z Dong, J Fang, P Wang, T Zhu, W Gong, R Fang, ... Cell research 23 (2), 306-309, 2013 | 52 | 2013 |
| Coordinated regulation of cellular identity–associated H3K4me3 breadth by the COMPASS family CC Sze, PA Ozark, K Cao, M Ugarenko, S Das, LU Wang, SA Marshall, ... Science advances 6 (26), eaaz4764, 2020 | 43 | 2020 |
| Coordinated regulation of RNA polymerase II pausing and elongation progression by PAF1 Z Wang, A Song, H Xu, S Hu, B Tao, L Peng, J Wang, J Li, J Yu, L Wang, ... Science Advances 8 (13), eabm5504, 2022 | 34 | 2022 |
| Structural basis of INTAC-regulated transcription H Zheng, Q Jin, X Wang, Y Qi, W Liu, Y Ren, D Zhao, F Xavier Chen, ... Protein & Cell 14 (9), 698-702, 2023 | 33* | 2023 |
| R-loop-dependent promoter-proximal termination ensures genome stability C Xu, C Li, J Chen, Y Xiong, Z Qiao, P Fan, C Li, S Ma, J Liu, A Song, ... Nature 621 (7979), 610-619, 2023 | 29 | 2023 |
| Synergy between arsenic trioxide and JQ1 on autophagy in pancreatic cancer C Xu, X Wang, Y Zhou, FX Chen, H Wang, K Li, H Fan, X Tang, G Jiang, ... Oncogene 38 (47), 7249-7265, 2019 | 24 | 2019 |
| INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II S Hu, L Peng, A Song, YX Ji, J Cheng, M Wang, FX Chen Molecular cell 83 (10), 1588-1604. e5, 2023 | 23 | 2023 |
| H3K4me2/3 modulate the stability of RNA polymerase II pausing S Hu, A Song, L Peng, N Tang, Z Qiao, Z Wang, F Lan, FX Chen Cell Research 33 (5), 403-406, 2023 | 18 | 2023 |
Ali ShilatifardProfessor and Chairman of Biochemistry, Director of Simpson Querrey Institute for Epigenetics在 northwestern.edu 的电子邮件经过验证
