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Deepa Rajasekaran
Deepa Rajasekaran
Associate Research Scientist, Yale University
在 yale.edu 的电子邮件经过验证
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引用次数
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An analysis of MIF structural features that control functional activation of CD74
G Pantouris, MA Syed, C Fan, D Rajasekaran, TY Cho, EM Rosenberg, ...
Chemistry & biology 22 (9), 1197-1205, 2015
1042015
Macrophage migration inhibitory factor-CXCR4 receptor interactions
D Rajasekaran, S Gröning, C Schmitz, S Zierow, N Drucker, M Bakou, ...
Journal of Biological Chemistry 291 (30), 15881-15895, 2016
992016
Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment
D Rajasekaran, S Zierow, M Syed, R Bucala, V Bhandari, EJ Lolis
The FASEB Journal 28 (11), 4961, 2014
802014
MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations
C Fan, D Rajasekaran, MA Syed, L Leng, JP Loria, V Bhandari, R Bucala, ...
Proceedings of the National Academy of Sciences 110 (27), 10994-10999, 2013
502013
N-and C-terminal cooperation in rotavirus enterotoxin: novel mechanism of modulation of the properties of a multifunctional protein by a structurally and functionally …
MR Jagannath, MM Kesavulu, R Deepa, PN Sastri, SS Kumar, K Suguna, ...
Journal of virology 80 (1), 412-425, 2006
442006
A model of GAG/MIP-2/CXCR2 interfaces and its functional effects
D Rajasekaran, C Keeler, MA Syed, MC Jones, JK Harrison, D Wu, ...
Biochemistry 51 (28), 5642-5654, 2012
322012
Structure of the extended diarrhea-inducing domain of rotavirus enterotoxigenic protein NSP4
R Deepa, C Durga Rao, K Suguna
Archives of virology 152, 847-859, 2007
312007
The flexible C terminus of the rotavirus non-structural protein NSP4 is an important determinant of its biological properties
D Rajasekaran, NP Sastri, JR Marathahalli, SS Indi, K Pamidimukkala, ...
Journal of general virology 89 (6), 1485-1496, 2008
262008
Characterization, dynamics, and mechanism of CXCR4 antagonists on a constitutively active mutant
EM Rosenberg, RES Harrison, LK Tsou, N Drucker, B Humphries, ...
Cell chemical biology 26 (5), 662-673. e7, 2019
252019
Crystallographic and Receptor Binding Characterization of Plasmodium falciparum Macrophage Migration Inhibitory Factor Complexed to Two Potent Inhibitors
G Pantouris, D Rajasekaran, A Baeza Garcia, VG Ruiz, L Leng, ...
Journal of medicinal chemistry 57 (20), 8652-8656, 2014
192014
Structural insight into the evolution of a new chemokine family from zebrafish
D Rajasekaran, C Fan, W Meng, JW Pflugrath, EJ Lolis
Proteins: Structure, Function, and Bioinformatics 82 (5), 708-716, 2014
72014
Expression, purification, crystallization and preliminary crystallographic analysis of the diarrhoea-causing and virulence-determining region of rotaviral nonstructural protein …
R Deepa, MR Jagannath, MM Kesavulu, C Durga Rao, K Suguna
Acta Crystallographica Section D: Biological Crystallography 60 (1), 135-136, 2004
72004
HTS driven by fluorescence lifetime detection of FRET identifies activators and inhibitors of cardiac myosin
JM Muretta, D Rajasekaran, Y Blat, S Little, M Myers, C Nair, B Burdekin, ...
SLAS Discovery 28 (5), 223-232, 2023
62023
The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity
EM Rosenberg Jr, J Herrington, D Rajasekaran, JW Murphy, G Pantouris, ...
Acta Crystallographica Section D: Structural Biology 76 (10), 1033-1049, 2020
32020
High-Throughput Screening of a Functional Human CXCL12-CXCR4 Signaling Axis in a Genetically Modified S. cerevisiae: Discovery of a Novel Up-Regulator of …
JW Murphy, D Rajasekaran, J Merkel, E Skeens, C Keeler, ME Hodsdon, ...
Frontiers in Molecular Biosciences 7, 164, 2020
32020
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