An analysis of MIF structural features that control functional activation of CD74 G Pantouris, MA Syed, C Fan, D Rajasekaran, TY Cho, EM Rosenberg, ... Chemistry & biology 22 (9), 1197-1205, 2015 | 104 | 2015 |
Macrophage migration inhibitory factor-CXCR4 receptor interactions D Rajasekaran, S Gröning, C Schmitz, S Zierow, N Drucker, M Bakou, ... Journal of Biological Chemistry 291 (30), 15881-15895, 2016 | 99 | 2016 |
Targeting distinct tautomerase sites of D-DT and MIF with a single molecule for inhibition of neutrophil lung recruitment D Rajasekaran, S Zierow, M Syed, R Bucala, V Bhandari, EJ Lolis The FASEB Journal 28 (11), 4961, 2014 | 80 | 2014 |
MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations C Fan, D Rajasekaran, MA Syed, L Leng, JP Loria, V Bhandari, R Bucala, ... Proceedings of the National Academy of Sciences 110 (27), 10994-10999, 2013 | 50 | 2013 |
N-and C-terminal cooperation in rotavirus enterotoxin: novel mechanism of modulation of the properties of a multifunctional protein by a structurally and functionally … MR Jagannath, MM Kesavulu, R Deepa, PN Sastri, SS Kumar, K Suguna, ... Journal of virology 80 (1), 412-425, 2006 | 44 | 2006 |
A model of GAG/MIP-2/CXCR2 interfaces and its functional effects D Rajasekaran, C Keeler, MA Syed, MC Jones, JK Harrison, D Wu, ... Biochemistry 51 (28), 5642-5654, 2012 | 32 | 2012 |
Structure of the extended diarrhea-inducing domain of rotavirus enterotoxigenic protein NSP4 R Deepa, C Durga Rao, K Suguna Archives of virology 152, 847-859, 2007 | 31 | 2007 |
The flexible C terminus of the rotavirus non-structural protein NSP4 is an important determinant of its biological properties D Rajasekaran, NP Sastri, JR Marathahalli, SS Indi, K Pamidimukkala, ... Journal of general virology 89 (6), 1485-1496, 2008 | 26 | 2008 |
Characterization, dynamics, and mechanism of CXCR4 antagonists on a constitutively active mutant EM Rosenberg, RES Harrison, LK Tsou, N Drucker, B Humphries, ... Cell chemical biology 26 (5), 662-673. e7, 2019 | 25 | 2019 |
Crystallographic and Receptor Binding Characterization of Plasmodium falciparum Macrophage Migration Inhibitory Factor Complexed to Two Potent Inhibitors G Pantouris, D Rajasekaran, A Baeza Garcia, VG Ruiz, L Leng, ... Journal of medicinal chemistry 57 (20), 8652-8656, 2014 | 19 | 2014 |
Structural insight into the evolution of a new chemokine family from zebrafish D Rajasekaran, C Fan, W Meng, JW Pflugrath, EJ Lolis Proteins: Structure, Function, and Bioinformatics 82 (5), 708-716, 2014 | 7 | 2014 |
Expression, purification, crystallization and preliminary crystallographic analysis of the diarrhoea-causing and virulence-determining region of rotaviral nonstructural protein … R Deepa, MR Jagannath, MM Kesavulu, C Durga Rao, K Suguna Acta Crystallographica Section D: Biological Crystallography 60 (1), 135-136, 2004 | 7 | 2004 |
HTS driven by fluorescence lifetime detection of FRET identifies activators and inhibitors of cardiac myosin JM Muretta, D Rajasekaran, Y Blat, S Little, M Myers, C Nair, B Burdekin, ... SLAS Discovery 28 (5), 223-232, 2023 | 6 | 2023 |
The N-terminal length and side-chain composition of CXCL13 affect crystallization, structure and functional activity EM Rosenberg Jr, J Herrington, D Rajasekaran, JW Murphy, G Pantouris, ... Acta Crystallographica Section D: Structural Biology 76 (10), 1033-1049, 2020 | 3 | 2020 |
High-Throughput Screening of a Functional Human CXCL12-CXCR4 Signaling Axis in a Genetically Modified S. cerevisiae: Discovery of a Novel Up-Regulator of … JW Murphy, D Rajasekaran, J Merkel, E Skeens, C Keeler, ME Hodsdon, ... Frontiers in Molecular Biosciences 7, 164, 2020 | 3 | 2020 |