Dissection of ESAT-6 System 1 of Mycobacterium tuberculosis and Impact on Immunogenicity and Virulence P Brodin, L Majlessi, L Marsollier, MI De Jonge, D Bottai, C Demangel, ... Infection and immunity 74 (1), 88-98, 2006 | 408 | 2006 |
ESAT-6 from Mycobacterium tuberculosis Dissociates from Its Putative Chaperone CFP-10 under Acidic Conditions and Exhibits Membrane-Lysing Activity MI De Jonge, G Pehau-Arnaudet, MM Fretz, F Romain, D Bottai, P Brodin, ... Journal of bacteriology 189 (16), 6028-6034, 2007 | 401 | 2007 |
Aged gut microbiota contributes to systemical inflammaging after transfer to germ-free mice F Fransen, AA Van Beek, T Borghuis, SE Aidy, F Hugenholtz, ... Frontiers in immunology 8, 1385, 2017 | 298 | 2017 |
The impact of gut microbiota on gender-specific differences in immunity F Fransen, AA van Beek, T Borghuis, B Meijer, F Hugenholtz, ... Frontiers in immunology 8, 754, 2017 | 232 | 2017 |
Functional analysis of early secreted antigenic target-6, the dominant T-cell antigen of Mycobacterium tuberculosis, reveals key residues involved in secretion, complex … P Brodin, MI de Jonge, L Majlessi, C Leclerc, M Nilges, ST Cole, R Brosch Journal of Biological Chemistry 280 (40), 33953-33959, 2005 | 182 | 2005 |
LifeTime and improving European healthcare through cell-based interceptive medicine N Rajewsky, G Almouzni, SA Gorski, S Aerts, I Amit, MG Bertero, C Bock, ... Nature 587 (7834), 377-386, 2020 | 139 | 2020 |
Invasive disease caused by nontypeable Haemophilus influenzae JD Langereis, MI de Jonge Emerging infectious diseases 21 (10), 1711, 2015 | 137 | 2015 |
Salmonella outer membrane vesicles displaying high densities of pneumococcal antigen at the surface offer protection against colonization K Kuipers, MH Daleke-Schermerhorn, WSP Jong, ... Vaccine 33 (17), 2022-2029, 2015 | 113 | 2015 |
Agglutination by anti-capsular polysaccharide antibody is associated with protection against experimental human pneumococcal carriage E Mitsi, AM Roche, J Reiné, T Zangari, JT Owugha, SH Pennington, ... Mucosal immunology 10 (2), 385-394, 2017 | 101 | 2017 |
SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms J Fröberg, J Gillard, R Philipsen, K Lanke, J Rust, D van Tuijl, K Teelen, ... Nature communications 12 (1), 5621, 2021 | 84 | 2021 |
For the greater good: Programmed cell death in bacterial communities SH Peeters, MI de Jonge Microbiological research 207, 161-169, 2018 | 83 | 2018 |
The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition AJH Cremers, AL Zomer, JF Gritzfeld, G Ferwerda, SAFT van Hijum, ... Microbiome 2, 1-10, 2014 | 80 | 2014 |
From microbial gene essentiality to novel antimicrobial drug targets FM Mobegi, SAFT van Hijum, P Burghout, HJ Bootsma, SPW de Vries, ... BMC genomics 15, 1-11, 2014 | 69 | 2014 |
PERISCOPE: road towards effective control of pertussis DA Diavatopoulos, KHG Mills, KE Kester, B Kampmann, M Silerova, ... The Lancet Infectious Diseases 19 (5), e179-e186, 2019 | 66 | 2019 |
Haemophilus is overrepresented in the nasopharynx of infants hospitalized with RSV infection and associated with increased viral load and enhanced mucosal … THA Ederveen, G Ferwerda, IM Ahout, M Vissers, R de Groot, J Boekhorst, ... Microbiome 6, 1-13, 2018 | 66 | 2018 |
Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system D Bottai, W Frigui, S Clark, E Rayner, A Zelmer, N Andreu, MI de Jonge, ... Vaccine 33 (23), 2710-2718, 2015 | 66 | 2015 |
Berberine and obatoclax inhibit SARS-Cov-2 replication in primary human nasal epithelial cells in vitro FS Varghese, E van Woudenbergh, GJ Overheul, MJ Eleveld, L Kurver, ... Viruses 13 (2), 282, 2021 | 64 | 2021 |
β2→ 1-fructans modulate the immune system in vivo in a microbiota-dependent and-independent fashion F Fransen, NM Sahasrabudhe, S El Aidy, H Smidt, HA Schols, P de Vos Frontiers in immunology 8, 242358, 2017 | 64 | 2017 |
Display of recombinant proteins on bacterial outer membrane vesicles by using protein ligation HB van den Berg van Saparoea, D Houben, MI de Jonge, WSP Jong, ... Applied and environmental microbiology 84 (8), e02567-17, 2018 | 63 | 2018 |
Intranasal immunisation of mice with liposomes containing recombinant meningococcal OpaB and OpaJ proteins MI de Jonge, HJ Hamstra, W Jiskoot, P Roholl, NA Williams, J Dankert, ... Vaccine 22 (29-30), 4021-4028, 2004 | 62 | 2004 |