Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice S Kumari, MC Bonnet, MH Ulvmar, K Wolk, N Karagianni, E Witte, ... Immunity 39 (5), 899-911, 2013 | 161 | 2013 |
Identification of microRNA-221/222 and microRNA-323-3p association with rheumatoid arthritis via predictions using the human tumour necrosis factor transgenic mouse model I Pandis, C Ospelt, N Karagianni, MC Denis, M Reczko, C Camps, ... Annals of the rheumatic diseases 71 (10), 1716-1723, 2012 | 128 | 2012 |
Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis M Roulis, C Nikolaou, E Kotsaki, E Kaffe, N Karagianni, V Koliaraki, ... Proceedings of the National Academy of Sciences 111 (43), E4658-E4667, 2014 | 98 | 2014 |
Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium F Van Hauwermeiren, M Armaka, N Karagianni, K Kranidioti, ... The Journal of clinical investigation 123 (6), 2590-2603, 2013 | 91 | 2013 |
Improved topical delivery of tacrolimus: a novel composite hydrogel formulation for the treatment of psoriasis D Gabriel, T Mugnier, H Courthion, K Kranidioti, N Karagianni, MC Denis, ... Journal of Controlled Release 242, 16-24, 2016 | 82 | 2016 |
Frailty in mouse ageing: A conceptual approach T von Zglinicki, I Varela-Nieto, D Brites, N Karagianni, S Ortolano, ... Mechanisms of ageing and development 160, 34-40, 2016 | 47 | 2016 |
Targeted metabolic profiling of the Tg197 mouse model reveals itaconic acid as a marker of rheumatoid arthritis F Michopoulos, N Karagianni, NM Whalley, MA Firth, C Nikolaou, ... Journal of proteome research 15 (12), 4579-4590, 2016 | 43 | 2016 |
Comorbid TNF-mediated heart valve disease and chronic polyarthritis share common mesenchymal cell-mediated aetiopathogenesis L Ntari, M Sakkou, P Chouvardas, I Mourouzis, A Prados, MC Denis, ... Annals of the Rheumatic Diseases 77 (6), 926-934, 2018 | 27 | 2018 |
Myeloid TAKL acts as a negative regulator of the LPS response and mediates resistance to endotoxemia C Eftychi, N Karagianni, M Alexiou, M Apostolaki, G Kollias PloS one 7 (2), e31550, 2012 | 26 | 2012 |
TNFα induces endothelial dysfunction in rheumatoid arthritis via LOX-1 and arginase 2: reversal by monoclonal TNFα antibodies A Akhmedov, M Crucet, B Simic, S Kraler, NR Bonetti, C Ospelt, O Distler, ... Cardiovascular Research 118 (1), 254-266, 2022 | 22 | 2022 |
Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis M Sakkou, P Chouvardas, L Ntari, A Prados, K Moreth, H Fuchs, ... JCI insight 3 (7), 2018 | 22 | 2018 |
Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis E Christodoulou-Vafeiadou, C Geka, L Ntari, K Kranidioti, E Argyropoulou, ... Arthritis research & therapy 22, 1-14, 2020 | 18 | 2020 |
The mouse filensin gene: structure and evolutionary relation to other intermediate filament genes F Gounari, N Karagianni, A Mincheva, P Lichter, SD Georgatos, ... FEBS letters 413 (2), 371-378, 1997 | 16 | 1997 |
Gene transfer and genetic modification of embryonic stem cells by Cre‐and Cre‐PR‐expressing MESV‐based retroviral vectors S Psarras, N Karagianni, C Kellendonk, F Tronche, FL Cosset, C Stocking, ... The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004 | 15 | 2004 |
An integrative transcriptome analysis framework for drug efficacy and similarity reveals drug-specific signatures of anti-TNF treatment in a mouse model of inflammatory … N Karagianni, K Kranidioti, N Fikas, M Tsochatzidou, P Chouvardas, ... PLoS Computational Biology 15 (5), e1006933, 2019 | 14 | 2019 |
Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis D Papadopoulou, F Roumelioti, C Tzaferis, P Chouvardas, AK Pedersen, ... JCI insight 8 (9), 2023 | 7 | 2023 |
TNF overexpression and dexamethasone treatment impair chondrogenesis and bone growth in an additive manner Y Zhao, B Celvin, MC Denis, N Karagianni, C Aulin, F Zaman, ... Scientific Reports 12 (1), 18189, 2022 | 6 | 2022 |
Combination of subtherapeutic anti-TNF dose with dasatinib restores clinical and molecular arthritogenic profiles better than standard anti-TNF treatment L Ntari, C Nikolaou, K Kranidioti, D Papadopoulou, ... Journal of translational medicine 19 (1), 165, 2021 | 6 | 2021 |
Novel adenomatous polyposis coli gene promoter is located 40 kb upstream of the initiating methionine N Karagianni, MC Ly, S Psarras, K Chlichlia, V Schirrmacher, F Gounari, ... Genomics 85 (2), 231-237, 2005 | 5 | 2005 |
Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression A Kaklamanos, J Rozman, M Roulis, N Karagianni, M Armaka, M Wu, ... Scientific reports 7 (1), 2397, 2017 | 3 | 2017 |