Kinetic basis for DNA target specificity of CRISPR-Cas12a I Strohkendl, FA Saifuddin, JR Rybarski, IJ Finkelstein, R Russell Molecular cell 71 (5), 816-824. e3, 2018 | 266 | 2018 |
Inhibition of CRISPR-Cas12a DNA targeting by nucleosomes and chromatin I Strohkendl, FA Saifuddin, BA Gibson, MK Rosen, R Russell, ... Science advances 7 (11), eabd6030, 2021 | 35 | 2021 |
Structural basis of Cas12a R-loop propagation on pathway to DNA cleavage I Strohkendl, C Moy, AH Nguyen, R Russell, DW Taylor bioRxiv, 2023.03. 13.532460, 2023 | 4 | 2023 |
Cas12a domain flexibility guides R-loop formation and forces RuvC resetting I Strohkendl, A Saha, C Moy, AH Nguyen, M Ahsan, R Russell, G Palermo, ... Molecular Cell, 2024 | | 2024 |
Folding and unfolding of an alpha-helical lid govern target double-stranded DNA break in Cas12a A Saha, I Strohkendl, M Ahsan, C Moy, AH Nguyen, R Russel, DW Taylor, ... Biophysical Journal 123 (3), 60a, 2024 | | 2024 |
Kinetic characterization of CRISPR-Cas12a DNA targeting IS Strohkendl | | 2021 |