Narcolepsy is strongly associated with the T-cell receptor alpha locus J Hallmayer, J Faraco, L Lin, S Hesselson, J Winkelmann, M Kawashima, ... Nature genetics 41 (6), 708-711, 2009 | 553 | 2009 |
Association of common genetic variation in the insulin/IGF1 signaling pathway with human longevity L Pawlikowska, D Hu, S Huntsman, A Sung, C Chu, J Chen, AH Joyner, ... Aging cell 8 (4), 460-472, 2009 | 412 | 2009 |
Alternative splicing in cancer: implications for biology and therapy J Chen, WA Weiss Oncogene 34 (1), 1-14, 2015 | 295 | 2015 |
Drugging MYCN through an Allosteric Transition in Aurora Kinase A WC Gustafson, JG Meyerowitz, EA Nekritz, J Chen, C Benes, E Charron, ... Cancer cell 26 (3), 414-427, 2014 | 290 | 2014 |
EGFR Phosphorylates Tumor-Derived EGFRvIII Driving STAT3/5 and Progression in Glioblastoma QW Fan, CK Cheng, WC Gustafson, E Charron, P Zipper, RA Wong, ... Cancer Cell 24 (4), 438-449, 2013 | 279 | 2013 |
Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC FJ Swartling, V Savov, AI Persson, J Chen, CS Hackett, PA Northcott, ... Cancer cell 21 (5), 601-613, 2012 | 240 | 2012 |
Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma BM Costa, JS Smith, Y Chen, J Chen, HS Phillips, KD Aldape, G Zardo, ... Cancer research 70 (2), 453-462, 2010 | 170 | 2010 |
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics X Huang, AM Dubuc, R Hashizume, J Berg, Y He, J Wang, C Chiang, ... Genes & Development 26 (16), 1780-1796, 2012 | 94 | 2012 |
Green technologies for room temperature nucleic acid storage E Wan, M Akana, J Pons, J Chen, S Musone, PY Kwok, W Liao Current issues in molecular biology 12 (3), 135, 2010 | 88 | 2010 |
Multi-faceted epigenetic dysregulation of gene expression promotes esophageal squamous cell carcinoma W Cao, H Lee, W Wu, A Zaman, S McCorkle, M Yan, J Chen, Q Xing, ... Nature communications 11 (1), 3675, 2020 | 84 | 2020 |
Differences in allergic sensitization by self-reported race and genetic ancestry JJ Yang, EG Burchard, S Choudhry, CC Johnson, DR Ownby, D Favro, ... Journal of Allergy and Clinical Immunology 122 (4), 820-827. e9, 2008 | 71 | 2008 |
Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis M Huang, J Tailor, Q Zhen, AH Gillmor, ML Miller, H Weishaupt, J Chen, ... Cell Stem Cell 25, 433-446, 2019 | 69 | 2019 |
Natural variation in four human collagen genes across an ethnically diverse population TF Chan, A Poon, A Basu, NR Addleman, J Chen, A Phong, PH Byers, ... Genomics 91 (4), 307-314, 2008 | 69 | 2008 |
HAT1 coordinates histone production and acetylation via H4 promoter binding JJ Gruber, B Geller, AM Lipchik, J Chen, AA Salahudeen, AN Ram, ... Molecular cell 75 (4), 711-724. e5, 2019 | 66 | 2019 |
Poly (ADP-Ribose) Polymerase Inhibitor MK-4827 together with Radiation as a Novel Therapy for Metastatic Neuroblastoma S Mueller, S Bhargava, AM Molinaro, X Yang, I Kolkowitz, A Olow, ... Anticancer research 33 (3), 755-762, 2013 | 38 | 2013 |
A maternally inherited chromosome 18q22. 1 deletion in a male with late‐presenting diaphragmatic hernia and microphthalmia–evaluation of DSEL as a candidate gene for the … H Zayed, R Chao, A Moshrefi, N LopezJimenez, A Delaney, J Chen, ... American Journal of Medical Genetics Part A 152 (4), 916-923, 2010 | 38 | 2010 |
Expression Quantitative Trait Loci and Receptor Pharmacology Implicate Arg1 and the GABA-A Receptor as Therapeutic Targets in Neuroblastoma CS Hackett, DA Quigley, RA Wong, J Chen, C Cheng, YK Song, JS Wei, ... Cell reports 9 (3), 1034-1046, 2014 | 24 | 2014 |
The genetics of splicing in neuroblastoma J Chen, CS Hackett, S Zhang, YK Song, RJA Bell, AM Molinaro, ... Cancer discovery 5 (4), 380-395, 2015 | 21 | 2015 |
High-Resolution Bisulfite-Sequencing of Peripheral Blood DNA Methylation in Early-Onset and Familial Risk Breast Cancer Patients J Chen, MK Haanpää, JJ Gruber, N Jäger, JM Ford, MP Snyder Clinical Cancer Research 25, 5301-5314, 2019 | 17 | 2019 |
Chromatin Remodeling in Response to BRCA2-Crisis JJ Gruber, J Chen, B Geller, N Jäger, AM Lipchik, G Wang, AW Kurian, ... Cell Reports 28 (8), 2182-2193. e6, 2019 | 13 | 2019 |