Glutamine triggers acetylation-dependent degradation of glutamine synthetase via the thalidomide receptor cereblon T Van Nguyen, JE Lee, MJ Sweredoski, SJ Yang, SJ Jeon, JS Harrison, ... Molecular cell 61 (6), 809-820, 2016 | 166 | 2016 |
SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation T Van Nguyen, P Angkasekwinai, H Dou, FM Lin, LS Lu, J Cheng, ... Molecular cell 45 (2), 210-221, 2012 | 129 | 2012 |
SUMOylation and de-SUMOylation in response to DNA damage H Dou, C Huang, T Van Nguyen, LS Lu, ETH Yeh FEBS letters 585 (18), 2891-2896, 2011 | 101 | 2011 |
DNA damage-induced cellular senescence is sufficient to suppress tumorigenesis: a mouse model T Van Nguyen, N Puebla-Osorio, H Pang, ME Dujka, C Zhu The Journal of Experimental Medicine 204 (6), 1453-1461, 2007 | 87 | 2007 |
p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates TV Nguyen, J Li, CC Lu, JL Mamrosh, G Lu, BE Cathers, RJ Deshaies Proceedings of the National Academy of Sciences 114 (14), 3565-3571, 2017 | 81 | 2017 |
Regulation of SOX11 expression through CCND1 and STAT3 in mantle cell lymphoma A Mohanty, N Sandoval, A Phan, TV Nguyen, RW Chen, E Budde, M Mei, ... Blood, The Journal of the American Society of Hematology 133 (4), 306-318, 2019 | 39 | 2019 |
USP15 antagonizes CRL4CRBN-mediated ubiquitylation of glutamine synthetase and neosubstrates TV Nguyen Proceedings of the National Academy of Sciences 118 (40), e2111391118, 2021 | 34 | 2021 |
Ubiquitin-dependent proteasomal degradation of AMPK gamma subunit by Cereblon inhibits AMPK activity SJ Yang, SJ Jeon, T Van Nguyen, RJ Deshaies, CS Park, KM Lee Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (8), 118729, 2020 | 23 | 2020 |
The CRL3gigaxonin ubiquitin ligase–USP15 pathway governs the destruction of neurofilament proteins HM Park, L Le, TT Nguyen, KH Nam, A Ordureau, JE Lee, TV Nguyen Proceedings of the National Academy of Sciences 120 (45), e2306395120, 2023 | 3 | 2023 |
Methods of using usp15 inhibitors TV Nguyen WO Patent WO2023039405A1, 2023 | | 2023 |
Sumo-Specific Protease 1 Controls Lymphoid Development Through Regulation Of Sumoylation/Acetylation Switch In Stat5 TV Nguyen | | 2011 |