| Comparison of VEGF, VEGF-B, VEGF-C and Ang-1 mRNA regulation by serum, growth factors, oncoproteins and hypoxia. B Enholm, K Paavonen, A Ristimäki, V Kumar, Y Gunji, J Klefstrom, ... Oncogene 14 (20), 2475, 1997 | 654 | 1997 |
| BCL2 overexpression associated with chromosomal amplification in diffuse large B-cell lymphoma O Monni, H Joensuu, K Franssila, J Klefstrom, K Alitalo, S Knuutila Blood, The Journal of the American Society of Hematology 90 (3), 1168-1174, 1997 | 275 | 1997 |
| c‐Myc induces cellular susceptibility to the cytotoxic action of TNF‐alpha. J Klefstrom, I Västrik, E Saksela, J Valle, M Eilers, K Alitalo The EMBO journal 13 (22), 5442-5450, 1994 | 179 | 1994 |
| The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo EW Verschuren, J Klefstrom, GI Evan, N Jones Cancer cell 2 (3), 229-241, 2002 | 174 | 2002 |
| Myc-induced AMPK-phospho p53 pathway activates Bak to sensitize mitochondrial apoptosis AI Nieminen, VM Eskelinen, HM Haikala, TA Tervonen, Y Yan, ... Proceedings of the National Academy of Sciences 110 (20), E1839-E1848, 2013 | 155 | 2013 |
| Induction of TNF‐sensitive cellular phenotype by c‐Myc involves p53 and impaired NF‐κB activation J Klefstrom, E Arighi, T Littlewood, M Jäättelä, E Saksela, GI Evan, ... The EMBO journal, 1997 | 144 | 1997 |
| Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization JI Partanen, AI Nieminen, TP Makela, J Klefstrom Proceedings of the National Academy of Sciences, 2007 | 133 | 2007 |
| Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity JI Partanen, TA Tervonen, M Myllynen, E Lind, M Imai, P Katajisto, ... Proceedings of the National Academy of Sciences 109 (7), E388-E397, 2012 | 114 | 2012 |
| Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer H Heinonen, A Nieminen, M Saarela, A Kallioniemi, J Klefström, ... BMC genomics 9, 1-12, 2008 | 109 | 2008 |
| Strain-stiffening of agarose gels K Bertula, L Martikainen, P Munne, S Hietala, J Klefström, O Ikkala, ... Acs macro letters 8 (6), 670-675, 2019 | 105 | 2019 |
| c-Myc augments the apoptotic activity of cytosolic death receptor signaling proteins by engaging the mitochondrial apoptotic pathway J Klefstrom, EW Verschuren, G Evan Journal of Biological Chemistry 277 (45), 43224-43232, 2002 | 104 | 2002 |
| c-Myc blazing a trail of death: coupling of the mitochondrial and death receptor apoptosis pathways by c-Myc AI Nieminen, JI Partanen, J Klefstrom Cell Cycle 6 (20), 2464-2472, 2007 | 93 | 2007 |
| c‐Myc primed mitochondria determine cellular sensitivity to TRAIL‐induced apoptosis AI Nieminen, JI Partanen, A Hau, J Klefstrom The EMBO journal 26 (4), 1055-1067, 2007 | 86 | 2007 |
| 3D view to tumor suppression: Lkb1, polarity and the arrest of oncogenic c-Myc JI Partanen, AI Nieminen, J Klefstrom Cell Cycle 8 (5), 716-724, 2009 | 74 | 2009 |
| Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy HM Haikala, JM Anttila, E Marques, T Raatikainen, M Ilander, H Hakanen, ... Nature communications 10 (1), 620, 2019 | 72 | 2019 |
| Serine 62-phosphorylated MYC associates with nuclear lamins and its regulation by CIP2A is essential for regenerative proliferation K Myant, X Qiao, T Halonen, C Come, A Laine, M Janghorban, ... Cell reports 12 (6), 1019-1031, 2015 | 72 | 2015 |
| Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic acid–induced 2 S Werner, B Brors, J Eick, E Marques, V Pogenberg, A Parret, D Kemming, ... Cancer discovery 5 (5), 506-519, 2015 | 57 | 2015 |
| Chk1 targeting reactivates PP2A tumor suppressor activity in cancer cells A Khanna, O Kauko, C Böckelman, A Laine, I Schreck, JI Partanen, ... Cancer research 73 (22), 6757-6769, 2013 | 57 | 2013 |
| Deregulated hepsin protease activity confers oncogenicity by concomitantly augmenting HGF/MET signalling and disrupting epithelial cohesion TA Tervonen, D Belitškin, SM Pant, JI Englund, E Marques, ... Oncogene 35 (14), 1832-1846, 2016 | 50 | 2016 |
| UBR5 is coamplified with MYC in breast tumors and encodes an ubiquitin ligase that limits MYC-dependent apoptosis X Qiao, Y Liu, ML Prada, AK Mohan, A Gupta, A Jaiswal, M Sharma, ... Cancer research 80 (7), 1414-1427, 2020 | 48 | 2020 |
