Transcription factor AP-2 essential for cranial closure and craniofacial development H Schorle, P Meier, M Buchert, R Jaenisch, PJ Mitchell Nature 381 (6579), 235-238, 1996 | 716 | 1996 |
STAT3 and STAT1 mediate IL-11–dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice M Ernst, M Najdovska, D Grail, T Lundgren-May, M Buchert, H Tye, ... The Journal of clinical investigation 118 (5), 1727-1738, 2008 | 405 | 2008 |
The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell–cell contact in the brain M Buchert, S Schneider, V Meskenaite, MT Adams, E Canaani, T Baechi, ... The Journal of cell biology 144 (2), 361-371, 1999 | 251 | 1999 |
Targeting JAK kinase in solid tumors: emerging opportunities and challenges M Buchert, CJ Burns, M Ernst Oncogene 35 (8), 939-951, 2016 | 237 | 2016 |
Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk MM Halford, J Armes, M Buchert, V Meskenaite, D Grail, ML Hibbs, ... Nature genetics 25 (4), 414-418, 2000 | 231 | 2000 |
The JAK/STAT3 axis: A comprehensive drug target for solid malignancies J Huynh, N Etemadi, F Hollande, M Ernst, M Buchert Seminars in cancer biology 45, 13-22, 2017 | 172 | 2017 |
IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization MF Eissmann, C Dijkstra, A Jarnicki, T Phesse, J Brunnberg, AR Poh, ... Nature communications 10 (1), 2735, 2019 | 164 | 2019 |
Defective claudin-7 regulation by Tcf-4 and Sox-9 disrupts the polarity and increases the tumorigenicity of colorectal cancer cells C Darido, M Buchert, J Pannequin, P Bastide, H Zalzali, T Mantamadiotis, ... Cancer research 68 (11), 4258-4268, 2008 | 137 | 2008 |
mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice S Thiem, TP Pierce, M Palmieri, TL Putoczki, M Buchert, A Preaudet, ... The Journal of clinical investigation 123 (2), 2013 | 130 | 2013 |
Mutagenesis and selection of PDZ domains that bind new protein targets S Schneider, M Buchert, O Georgiev, B Catimel, M Halford, SA Stacker, ... Nature biotechnology 17 (2), 170-175, 1999 | 125 | 1999 |
DNA-methylation-dependent alterations of claudin-4 expression in human bladder carcinoma S Boireau, M Buchert, MS Samuel, J Pannequin, JL Ryan, A Choquet, ... Carcinogenesis 28 (2), 246-258, 2007 | 107 | 2007 |
An in vitro assay of β-galactosidase from yeast S Schneider, M Buchert, CM Hovens Biotechniques 20 (6), 960-962, 1996 | 106 | 1996 |
Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/β-Catenin Pathway In Vivo M Buchert, D Athineos, HE Abud, ZD Burke, MC Faux, MS Samuel, ... PLoS genetics 6 (1), e1000816, 2010 | 104 | 2010 |
Symplekin promotes tumorigenicity by up-regulating claudin-2 expression M Buchert, M Papin, C Bonnans, C Darido, WS Raye, V Garambois, ... Proceedings of the National Academy of Sciences 107 (6), 2628-2633, 2010 | 91 | 2010 |
Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin E Kavanagh, M Buchert, A Tsapara, A Choquet, MS Balda, F Hollande, ... Journal of cell science 119 (24), 5098-5105, 2006 | 86 | 2006 |
Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt–β-catenin–mediated intestinal tumor growth and regeneration TJ Phesse, M Buchert, E Stuart, DJ Flanagan, M Faux, S Afshar-Sterle, ... Science signaling 7 (345), ra92-ra92, 2014 | 76 | 2014 |
Biochemical and structural insights into doublecortin-like kinase domain 1 O Patel, W Dai, M Mentzel, MDW Griffin, J Serindoux, Y Gay, S Fischer, ... Structure 24 (9), 1550-1561, 2016 | 60 | 2016 |
Distinct requirements for the Sprouty domain for functional activity of Spred proteins JAJ King, AFL Straffon, GM D'ABACO, CLC Poon, STT I, CM Smith, ... Biochemical Journal 388 (2), 445-454, 2005 | 54 | 2005 |
β-Catenin/Tcf-4 inhibition after progastrin targeting reduces growth and drives differentiation of intestinal tumors J Pannequin, N Delaunay, M Buchert, F Surrel, JF Bourgaux, J Ryan, ... Gastroenterology 133 (5), 1554-1568, 2007 | 50 | 2007 |
MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors A Sakthianandeswaren, MJ Parsons, D Mouradov, RN MacKinnon, ... Cancer discovery 8 (8), 988-1005, 2018 | 49 | 2018 |