Addiction to c-MYC in multiple myeloma T Holien, TK Våtsveen, H Hella, A Waage, A Sundan Blood, The Journal of the American Society of Hematology 120 (12), 2450-2453, 2012 | 194 | 2012 |
Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B OE Olsen, KF Wader, H Hella, AK Mylin, I Turesson, I Nesthus, A Waage, ... Cell communication and signaling 13, 1-7, 2015 | 150 | 2015 |
Targeting proliferating cell nuclear antigen and its protein interactions induces apoptosis in multiple myeloma cells R Müller, K Misund, T Holien, S Bachke, KM Gilljam, TK Våtsveen, TB Rø, ... PloS one 8 (7), e70430, 2013 | 120 | 2013 |
Overexpression and involvement in migration by the metastasis-associated phosphatase PRL-3 in human myeloma cells UM Fagerli, RU Holt, T Holien, TK Vaatsveen, F Zhan, KW Egeberg, ... Blood, The Journal of the American Society of Hematology 111 (2), 806-815, 2008 | 112 | 2008 |
Perturbation of the c-Myc–Max protein–protein interaction via synthetic α-helix mimetics KY Jung, H Wang, P Teriete, JL Yap, L Chen, ME Lanning, A Hu, ... Journal of medicinal chemistry 58 (7), 3002-3024, 2015 | 110 | 2015 |
Serum/glucocorticoid-regulated kinase 1 (SGK1) is a prominent target gene of the transcriptional response to cytokines in multiple myeloma and supports the growth of myeloma cells UM Fagerli, K Ullrich, T Stühmer, T Holien, K Köchert, RU Holt, O Bruland, ... Oncogene 30 (28), 3198-3206, 2011 | 85 | 2011 |
Artesunate shows potent anti-tumor activity in B-cell lymphoma TK Våtsveen, MR Myhre, CB Steen, S Wälchli, OC Lingjærde, B Bai, ... Journal of hematology & oncology 11, 1-12, 2018 | 81 | 2018 |
TGF-β contamination of purified recombinant GDF15 OE Olsen, A Skjærvik, BF Størdal, A Sundan, T Holien PloS one 12 (11), e0187349, 2017 | 72 | 2017 |
Monitoring multiple myeloma by quantification of recurrent mutations in serum EH Rustad, E Coward, ER Skytøen, K Misund, T Holien, T Standal, ... haematologica 102 (7), 1266, 2017 | 66 | 2017 |
c‐Met signaling promotes IL‐6‐induced myeloma cell proliferation H Hov, E Tian, T Holien, RU Holt, TK Våtsveen, UM Fagerli, A Waage, ... European journal of haematology 82 (4), 277-287, 2009 | 64 | 2009 |
Receptor binding competition: A paradigm for regulating TGF-β family action E Martinez-Hackert, A Sundan, T Holien Cytokine & growth factor reviews 57, 39-54, 2021 | 63 | 2021 |
BMPR2 inhibits activin and BMP signaling via wild-type ALK2 OE Olsen, M Sankar, S Elsaadi, H Hella, G Buene, SR Darvekar, ... Journal of cell science 131 (11), jcs213512, 2018 | 62 | 2018 |
Bone morphogenetic protein-9 suppresses growth of myeloma cells by signaling through ALK2 but is inhibited by endoglin OE Olsen, KF Wader, K Misund, TK Våtsveen, TB Rø, AK Mylin, ... Blood cancer journal 4 (3), e196-e196, 2014 | 61 | 2014 |
Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids H Wang, P Teriete, A Hu, D Raveendra-Panickar, K Pendelton, JS Lazo, ... Oncotarget 6 (32), 32380, 2015 | 59 | 2015 |
Intracellular glutathione determines bortezomib cytotoxicity in multiple myeloma cells KK Starheim, T Holien, K Misund, I Johansson, KA Baranowska, ... Blood cancer journal 6 (7), e446-e446, 2016 | 58 | 2016 |
Bone morphogenetic proteins induce apoptosis in multiple myeloma cells by Smad-dependent repression of MYC T Holien, TK Våtsveen, H Hella, C Rampa, G Brede, LAG Grøseth, ... Leukemia 26 (5), 1073-1080, 2012 | 56 | 2012 |
Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple … M Westhrin, SH Moen, T Holien, AK Mylin, L Heickendorff, OE Olsen, ... haematologica 100 (12), e511, 2015 | 55 | 2015 |
Ephrin-B2 is a candidate ligand for the Eph receptor, EphB6 E Munthe, E Rian, T Holien, AM Rasmussen, FO Levy, HC Aasheim FEBS letters 466 (1), 169-174, 2000 | 55 | 2000 |
GREM1 is associated with metastasis and predicts poor prognosis in ER-negative breast cancer patients U Neckmann, C Wolowczyk, M Hall, E Almaas, J Ren, S Zhao, ... Cell Communication and Signaling 17, 1-17, 2019 | 49 | 2019 |
Lymphoma and myeloma cells are highly sensitive to growth arrest and apoptosis induced by artesunate T Holien, OE Olsen, K Misund, H Hella, A Waage, TB Rø, A Sundan European Journal of Haematology 91 (4), 339-346, 2013 | 49 | 2013 |