| Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite G Cerutti, Y Guo, T Zhou, J Gorman, M Lee, M Rapp, ER Reddem, J Yu, ... Cell host & microbe 29 (5), 819-833. e7, 2021 | 473 | 2021 |
| Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1 K Xu, P Acharya, R Kong, C Cheng, GY Chuang, K Liu, MK Louder, ... Nature medicine 24 (6), 857-867, 2018 | 277 | 2018 |
| DeepSol: a deep learning framework for sequence-based protein solubility prediction S Khurana, R Rawi, K Kunji, GY Chuang, H Bensmail, R Mall Bioinformatics 34 (15), 2605-2613, 2018 | 188 | 2018 |
| Quantification of the impact of the HIV-1-glycan shield on antibody elicitation T Zhou, NA Doria-Rose, C Cheng, GBE Stewart-Jones, GY Chuang, ... Cell reports 19 (4), 719-732, 2017 | 183 | 2017 |
| Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529 M Pancera, YT Lai, T Bylund, A Druz, S Narpala, S O'Dell, A Schön, ... Nature chemical biology 13 (10), 1115-1122, 2017 | 134 | 2017 |
| Antibody lineages with vaccine-induced antigen-binding hotspots develop broad HIV neutralization R Kong, H Duan, Z Sheng, K Xu, P Acharya, X Chen, C Cheng, ... Cell 178 (3), 567-584. e19, 2019 | 108 | 2019 |
| Completeness of HIV-1 envelope glycan shield at transmission determines neutralization breadth K Wagh, EF Kreider, Y Li, HJ Barbian, GH Learn, E Giorgi, PT Hraber, ... Cell reports 25 (4), 893-908. e7, 2018 | 103 | 2018 |
| PaRSnIP: sequence-based protein solubility prediction using gradient boosting machine R Rawi, R Mall, K Kunji, CH Shen, PD Kwong, GY Chuang Bioinformatics 34 (7), 1092-1098, 2018 | 94 | 2018 |
| Longitudinal analysis reveals early development of three MPER-directed neutralizing antibody lineages from an HIV-1-infected individual SJ Krebs, YD Kwon, CA Schramm, WH Law, G Donofrio, KH Zhou, S Gift, ... Immunity 50 (3), 677-691. e13, 2019 | 87 | 2019 |
| A neutralizing antibody recognizing primarily N-linked glycan targets the silent face of the HIV envelope T Zhou, A Zheng, U Baxa, GY Chuang, IS Georgiev, R Kong, S O’Dell, ... Immunity 48 (3), 500-513. e6, 2018 | 81 | 2018 |
| Structural survey of broadly neutralizing antibodies targeting the HIV-1 Env trimer delineates epitope categories and characteristics of recognition GY Chuang, J Zhou, P Acharya, R Rawi, CH Shen, Z Sheng, B Zhang, ... Structure 27 (1), 196-206. e6, 2019 | 75 | 2019 |
| Surface-matrix screening identifies semi-specific interactions that improve potency of a near pan-reactive HIV-1-neutralizing antibody YD Kwon, GY Chuang, B Zhang, RT Bailer, NA Doria-Rose, TS Gindin, ... Cell reports 22 (7), 1798-1809, 2018 | 62 | 2018 |
| Structure of super-potent antibody CAP256-VRC26. 25 in complex with HIV-1 envelope reveals a combined mode of trimer-apex recognition J Gorman, GY Chuang, YT Lai, CH Shen, JC Boyington, A Druz, H Geng, ... Cell reports 31 (1), 2020 | 58 | 2020 |
| Complete functional mapping of infection-and vaccine-elicited antibodies against the fusion peptide of HIV AS Dingens, P Acharya, HK Haddox, R Rawi, K Xu, GY Chuang, H Wei, ... PLoS pathogens 14 (7), e1007159, 2018 | 56 | 2018 |
| Soluble prefusion closed DS-SOSIP. 664-Env trimers of diverse HIV-1 strains MG Joyce, IS Georgiev, Y Yang, A Druz, H Geng, GY Chuang, Y Do Kwon, ... Cell reports 21 (10), 2992-3002, 2017 | 52 | 2017 |
| Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting C Cheng, K Xu, R Kong, GY Chuang, AR Corrigan, H Geng, KR Hill, ... PloS one 14 (4), e0215163, 2019 | 46 | 2019 |
| Automated design by structure-based stabilization and consensus repair to achieve prefusion-closed envelope trimers in a wide variety of HIV strains R Rawi, L Rutten, YT Lai, AS Olia, S Blokland, J Juraszek, CH Shen, ... Cell reports 33 (8), 2020 | 36 | 2020 |
| Preclinical development of a fusion peptide conjugate as an HIV vaccine immunogen L Ou, WP Kong, GY Chuang, M Ghosh, K Gulla, S O’Dell, J Varriale, ... Scientific reports 10 (1), 3032, 2020 | 35 | 2020 |
| Accurate prediction for antibody resistance of clinical HIV-1 isolates R Rawi, R Mall, CH Shen, SK Farney, A Shiakolas, J Zhou, H Bensmail, ... Scientific reports 9 (1), 14696, 2019 | 33 | 2019 |
| BCrystal: an interpretable sequence-based protein crystallization predictor A Elbasir, R Mall, K Kunji, R Rawi, Z Islam, GY Chuang, PR Kolatkar, ... Bioinformatics 36 (5), 1429-1438, 2020 | 31 | 2020 |
