Cigarette smoke–induced neurogenic inflammation is mediated by α, β-unsaturated aldehydes and the TRPA1 receptor in rodents E Andre, B Campi, S Materazzi, M Trevisani, S Amadesi, D Massi, ... The Journal of clinical investigation 118 (7), 2574-2582, 2008 | 495 | 2008 |
The TGR5 receptor mediates bile acid–induced itch and analgesia F Alemi, E Kwon, DP Poole, TM Lieu, V Lyo, F Cattaruzza, F Cevikbas, ... The Journal of clinical investigation 123 (4), 1513-1530, 2013 | 398 | 2013 |
The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice F Alemi, DP Poole, J Chiu, K Schoonjans, F Cattaruzza, JR Grider, ... Gastroenterology 144 (1), 145-154, 2013 | 326 | 2013 |
Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system DP Poole, C Godfrey, F Cattaruzza, GS Cottrell, JG Kirkland, JC Pelayo, ... Neurogastroenterology & Motility 22 (7), 814-e228, 2010 | 239 | 2010 |
The bile acid receptor TGR5 activates the TRPA1 channel to induce itch in mice TM Lieu, G Jayaweera, P Zhao, DP Poole, D Jensen, M Grace, P McIntyre, ... Gastroenterology 147 (6), 1417-1428, 2014 | 227 | 2014 |
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ... Science Translational Medicine 9 (392), eaal3447, 2017 | 199 | 2017 |
The involvement of nitric oxide synthase neurons in enteric neuropathies LR Rivera, DP Poole, M Thacker, JB Furness Neurogastroenterology & Motility 23 (11), 980-988, 2011 | 190 | 2011 |
Protease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling DP Poole, S Amadesi, NA Veldhuis, FC Abogadie, TM Lieu, W Darby, ... Journal of biological chemistry 288 (8), 5790-5802, 2013 | 169 | 2013 |
The G protein–coupled receptor–transient receptor potential channel axis: molecular insights for targeting disorders of sensation and inflammation NA Veldhuis, DP Poole, M Grace, P McIntyre, NW Bunnett Pharmacological Reviews 67 (1), 36-73, 2015 | 168 | 2015 |
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission RE Yarwood, WL Imlach, TM Lieu, NA Veldhuis, DD Jensen, ... Proceedings of the National Academy of Sciences 114 (46), 12309-12314, 2017 | 156 | 2017 |
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome NN Jimenez-Vargas, LA Pattison, P Zhao, TM Lieu, R Latorre, DD Jensen, ... Proceedings of the National Academy of Sciences 115 (31), E7438-E7447, 2018 | 151 | 2018 |
The distribution of purine P2X2 receptors in the guinea-pig enteric nervous system P Castelucci, HL Robbins, DP Poole, JB Furness Histochemistry and cell biology 117, 415-422, 2002 | 146 | 2002 |
Quantification and potential functions of endogenous agonists of transient receptor potential channels in patients with irritable bowel syndrome N Cenac, T Bautzova, P Le Faouder, NA Veldhuis, DP Poole, C Rolland, ... Gastroenterology 149 (2), 433-444. e7, 2015 | 134 | 2015 |
The distribution of P2X3 purine receptor subunits in the guinea pig enteric nervous system DP Poole, P Castelucci, HL Robbins, R Chiocchetti, JB Furness Autonomic Neuroscience 101 (1-2), 39-47, 2002 | 120 | 2002 |
A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain PD Ramírez-García, JS Retamal, P Shenoy, W Imlach, M Sykes, N Truong, ... Nature nanotechnology 14 (12), 1150-1159, 2019 | 118 | 2019 |
Evidence that two forms of choline acetyltransferase are differentially expressed in subclasses of enteric neurons R Chiocchetti, DP Poole, H Kimura, Y Aimi, HL Robbins, P Castelucci, ... Cell and tissue research 311, 11-22, 2003 | 114 | 2003 |
Enteric glia modulate macrophage phenotype and visceral sensitivity following inflammation V Grubišić, JL McClain, DE Fried, I Grants, P Rajasekhar, E Csizmadia, ... Cell reports 32 (10), 2020 | 112 | 2020 |
Transient receptor potential ion channels V4 and A1 contribute to pancreatitis pain in mice E Ceppa, F Cattaruzza, V Lyo, S Amadesi, JC Pelayo, DP Poole, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 299 (3 …, 2010 | 110 | 2010 |
Transient receptor potential ankyrin 1 is expressed by inhibitory motoneurons of the mouse intestine DP Poole, JC Pelayo, F Cattaruzza, YM Kuo, G Gai, JV Chiu, R Bron, ... Gastroenterology 141 (2), 565-575. e4, 2011 | 102 | 2011 |
The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts DD Jensen, CB Godfrey, C Niklas, M Canals, M Kocan, DP Poole, ... Journal of Biological Chemistry 288 (32), 22942-22960, 2013 | 88 | 2013 |