Ageing as a risk factor for disease T Niccoli, L Partridge Current biology 22 (17), R741-R752, 2012 | 1863 | 2012 |
C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins S Mizielinska, S Grönke, T Niccoli, CE Ridler, EL Clayton, A Devoy, ... Science 345 (6201), 1192-1194, 2014 | 795 | 2014 |
G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ... EMBO molecular medicine 10 (1), 22-31, 2018 | 216 | 2018 |
Capu and Spire assemble a cytoplasmic actin mesh that maintains microtubule organization in the Drosophila oocyte K Dahlgaard, AASF Raposo, T Niccoli, D St Johnston Developmental cell 13 (4), 539-553, 2007 | 184 | 2007 |
Increased glucose transport into neurons rescues Aβ toxicity in Drosophila T Niccoli, M Cabecinha, A Tillmann, F Kerr, CT Wong, D Cardenes, ... Current Biology 26 (17), 2291-2300, 2016 | 125 | 2016 |
C9orf72 arginine-rich dipeptide proteins interact with ribosomal proteins in vivo to induce a toxic translational arrest that is rescued by eIF1A TG Moens, T Niccoli, KM Wilson, ML Atilano, N Birsa, LM Gittings, ... Acta Neuropathologica 137, 487-500, 2019 | 123 | 2019 |
RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats SB Yamada, TF Gendron, T Niccoli, NR Genuth, R Grosely, Y Shi, I Glaria, ... Nature neuroscience 22 (9), 1383-1388, 2019 | 95 | 2019 |
Ageing as a risk factor for ALS/FTD T Niccoli, L Partridge, AM Isaacs Human molecular genetics 26 (R2), R105-R113, 2017 | 94 | 2017 |
Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD TG Moens, S Mizielinska, T Niccoli, JS Mitchell, A Thoeng, CE Ridler, ... Acta neuropathologica 135, 445-457, 2018 | 82 | 2018 |
Cell-nonautonomous effects of dFOXO/DAF-16 in aging N Alic, JM Tullet, T Niccoli, S Broughton, MP Hoddinott, C Slack, D Gems, ... Cell reports 6 (4), 608-616, 2014 | 64 | 2014 |
Tea3p is a cell end marker activating polarized growth in Schizosaccharomyces pombe M Arellano, T Niccoli, P Nurse Current biology 12 (9), 751-756, 2002 | 62 | 2002 |
The p150-Glued Ssm4p regulates microtubular dynamics and nuclear movement in fission yeast T Niccoli, A Yamashita, P Nurse, M Yamamoto Journal of cell science 117 (23), 5543-5556, 2004 | 47 | 2004 |
Role of Tea1p, Tea3p and Pom1p in the determination of cell ends in Schizosaccharomyces pombe T Niccoli, M Arellano, P Nurse Yeast 20 (16), 1349-1358, 2003 | 28 | 2003 |
Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila ML Atilano, S Grönke, T Niccoli, L Kempthorne, O Hahn, J Moron-Oset, ... Elife 10, e58565, 2021 | 23 | 2021 |
Different mechanisms of cell polarisation in vegetative and shmooing growth in fission yeast T Niccoli, P Nurse Journal of Cell Science 115 (8), 1651-1662, 2002 | 21 | 2002 |
Mitochondria Dysfunction in Frontotemporal Dementia/Amyotrophic Lateral Sclerosis: Lessons From Drosophila Models S Anoar, NS Woodling, T Niccoli Frontiers in Neuroscience 15, 786076, 2021 | 19 | 2021 |
PICALM rescues glutamatergic neurotransmission, behavioural function and survival in a Drosophila model of Aβ42 toxicity Y Yu, T Niccoli, Z Ren, NS Woodling, B Aleyakpo, G Szabadkai, ... Human molecular genetics 29 (14), 2420-2434, 2020 | 18 | 2020 |
Cell type-specific modulation of healthspan by Forkhead family transcription factors in the nervous system E Bolukbasi, NS Woodling, DK Ivanov, J Adcott, A Foley, A Rajasingam, ... Proceedings of the National Academy of Sciences 118 (8), e2011491118, 2021 | 13 | 2021 |
Frontotemporal dementia and glucose metabolism LR Garrett, T Niccoli Frontiers in Neuroscience 16, 812222, 2022 | 12 | 2022 |
Activating transcription factor 4-dependent lactate dehydrogenase activation as a protective response to amyloid beta toxicity T Niccoli, F Kerr, I Snoeren, D Fabian, B Aleyakpo, D Ivanov, ... Brain communications 3 (2), fcab053, 2021 | 9 | 2021 |