Immunodeficiency in protein kinase Cβ-deficient mice M Leitges, C Schmedt, R Guinamard, J Davoust, S Schaal, S Stabel, ... Science 273 (5276), 788-791, 1996 | 575 | 1996 |
Activation of PKC-δ and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy P Geraldes, J Hiraoka-Yamamoto, M Matsumoto, A Clermont, M Leitges, ... Nature medicine 15 (11), 1298-1306, 2009 | 511 | 2009 |
Targeted disruption of the ζPKC gene results in the impairment of the NF-κB pathway M Leitges, L Sanz, P Martin, A Duran, U Braun, JF Garcı́a, F Camacho, ... Molecular cell 8 (4), 771-780, 2001 | 488 | 2001 |
PKC-β controls IκB kinase lipid raft recruitment and activation in response to BCR signaling TT Su, B Guo, Y Kawakami, K Sommer, K Chae, LA Humphries, RM Kato, ... Nature immunology 3 (8), 780-786, 2002 | 423 | 2002 |
Protein Kinase C θ Affects Ca2+ Mobilization and NFAT Activation in Primary Mouse T Cells C Pfeifhofer, K Kofler, T Gruber, N Ghaffari Tabrizi, C Lutz, K Maly, ... The Journal of experimental medicine 197 (11), 1525-1535, 2003 | 400 | 2003 |
The atypical PKC-interacting protein p62 is an important mediator of RANK-activated osteoclastogenesis A Durán, M Serrano, M Leitges, JM Flores, S Picard, JP Brown, J Moscat, ... Developmental cell 6 (2), 303-309, 2004 | 361 | 2004 |
Protein kinase Mζ synthesis from a brain mRNA encoding an independent protein kinase Cζ catalytic domain: implications for the molecular mechanism of memory AI Hernandez, N Blace, JF Crary, PA Serrano, M Leitges, JM Libien, ... Journal of Biological Chemistry 278 (41), 40305-40316, 2003 | 341 | 2003 |
Protein kinase Cδ controls self-antigen-induced B-cell tolerance I Mecklenbräuker, K Saijo, NY Zheng, M Leitges, A Tarakhovsky Nature 416 (6883), 860-865, 2002 | 332 | 2002 |
Syk kinase-coupled C-type lectin receptors engage protein kinase C-δ to elicit Card9 adaptor-mediated innate immunity D Strasser, K Neumann, H Bergmann, MJ Marakalala, R Guler, ... Immunity 36 (1), 32-42, 2012 | 308 | 2012 |
Exacerbated vein graft arteriosclerosis in protein kinase Cδ–null mice M Leitges, M Mayr, U Braun, U Mayr, C Li, G Pfister, N Ghaffari-Tabrizi, ... The Journal of clinical investigation 108 (10), 1505-1512, 2001 | 306 | 2001 |
12R-lipoxygenase deficiency disrupts epidermal barrier function N Epp, G Fürstenberger, K Müller, S de Juanes, M Leitges, I Hausser, ... The Journal of cell biology 177 (1), 173-182, 2007 | 245 | 2007 |
Mutant KRas-induced mitochondrial oxidative stress in acinar cells upregulates EGFR signaling to drive formation of pancreatic precancerous lesions GY Liou, H Döppler, KE DelGiorno, L Zhang, M Leitges, HC Crawford, ... Cell reports 14 (10), 2325-2336, 2016 | 244 | 2016 |
Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo DR Clayburgh, MW Musch, M Leitges, YX Fu, JR Turner The Journal of clinical investigation 116 (10), 2682-2694, 2006 | 225 | 2006 |
Protein kinase C-β contributes to NADPH oxidase activation in neutrophils LV DEKKER, M LEITGES, G ALTSCHULER, N MISTRY, A MCDERMOTT, ... Biochemical Journal 347 (1), 285-289, 2000 | 212 | 2000 |
AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis CM Louie, G Caridi, VS Lopes, F Brancati, A Kispert, MA Lancaster, ... Nature genetics 42 (2), 175-180, 2010 | 206 | 2010 |
Characterization of protein kinase C β isoform's action on retinoblastoma protein phosphorylation, vascular endothelial growth factor-induced endothelial cell proliferation … K Suzuma, N Takahara, I Suzuma, K Isshiki, K Ueki, M Leitges, LP Aiello, ... Proceedings of the National Academy of Sciences 99 (2), 721-726, 2002 | 205 | 2002 |
Muscle-specific knockout of PKC-λ impairs glucose transport and induces metabolic and diabetic syndromes RV Farese, MP Sajan, H Yang, P Li, S Mastorides, WR Gower, S Nimal, ... The Journal of clinical investigation 117 (8), 2289-2301, 2007 | 203 | 2007 |
A role for the β isoform of protein kinase C in fear conditioning EJ Weeber, CM Atkins, JC Selcher, AW Varga, B Mirnikjoo, R Paylor, ... Journal of Neuroscience 20 (16), 5906-5914, 2000 | 201 | 2000 |
Protein kinase c-β-dependent activation of NF-κB in stromal cells is indispensable for the survival of chronic lymphocytic leukemia B cells in vivo G Lutzny, T Kocher, M Schmidt-Supprian, M Rudelius, L Klein-Hitpass, ... Cancer cell 23 (1), 77-92, 2013 | 198 | 2013 |
Control of nutrient stress-induced metabolic reprogramming by PKCζ in tumorigenesis L Ma, Y Tao, A Duran, V Llado, A Galvez, JF Barger, EA Castilla, J Chen, ... Cell 152 (3), 599-611, 2013 | 197 | 2013 |