| Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers J Laurén, DA Gimbel, HB Nygaard, JW Gilbert, SM Strittmatter Nature 457 (7233), 1128-1132, 2009 | 1919 | 2009 |
| Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons JW Um, HB Nygaard, JK Heiss, MA Kostylev, M Stagi, A Vortmeyer, ... Nature neuroscience 15 (9), 1227-1235, 2012 | 747 | 2012 |
| Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein JW Um, AC Kaufman, M Kostylev, JK Heiss, M Stagi, H Takahashi, ... Neuron 79 (5), 887-902, 2013 | 636 | 2013 |
| Memory impairment in transgenic Alzheimer mice requires cellular prion protein DA Gimbel, HB Nygaard, EE Coffey, EC Gunther, J Laurén, ZA Gimbel, ... Journal of Neuroscience 30 (18), 6367-6374, 2010 | 510 | 2010 |
| Epileptic activity in Alzheimer's disease: causes and clinical relevance KA Vossel, MC Tartaglia, HB Nygaard, AZ Zeman, BL Miller The Lancet Neurology 16 (4), 311-322, 2017 | 493 | 2017 |
| An unbiased expression screen for synaptogenic proteins identifies the LRRTM protein family as synaptic organizers MW Linhoff, J Laurén, RM Cassidy, FA Dobie, H Takahashi, HB Nygaard, ... Neuron 61 (5), 734-749, 2009 | 405 | 2009 |
| World‐Wide FINGERS Network: a global approach to risk reduction and prevention of dementia M Kivipelto, F Mangialasche, HM Snyder, R Allegri, S Andrieu, H Arai, ... Alzheimer's & dementia 16 (7), 1078-1094, 2020 | 357 | 2020 |
| F yn inhibition rescues established memory and synapse loss in A lzheimer mice AC Kaufman, SV Salazar, LT Haas, J Yang, MA Kostylev, AT Jeng, ... Annals of neurology 77 (6), 953-971, 2015 | 325 | 2015 |
| Fyn kinase inhibition as a novel therapy for Alzheimer’s disease HB Nygaard, CH van Dyck, SM Strittmatter Alzheimer's research & therapy 6, 1-8, 2014 | 216 | 2014 |
| Genetic reduction of striatal-enriched tyrosine phosphatase (STEP) reverses cognitive and cellular deficits in an Alzheimer’s disease mouse model Y Zhang, P Kurup, J Xu, N Carty, SM Fernandez, HB Nygaard, C Pittenger, ... Proceedings of the National Academy of Sciences 107 (44), 19014-19019, 2010 | 204 | 2010 |
| A phase Ib multiple ascending dose study of the safety, tolerability, and central nervous system availability of AZD0530 (saracatinib) in Alzheimer’s disease HB Nygaard, AF Wagner, GS Bowen, SP Good, MG MacAvoy, ... Alzheimer's research & therapy 7, 1-11, 2015 | 152 | 2015 |
| Targeting Fyn kinase in Alzheimer’s disease HB Nygaard Biological psychiatry 83 (4), 369-376, 2018 | 147 | 2018 |
| Prion-protein-interacting amyloid-β oligomers of high molecular weight are tightly correlated with memory impairment in multiple Alzheimer mouse models MA Kostylev, AC Kaufman, HB Nygaard, P Patel, LT Haas, EC Gunther, ... Journal of Biological Chemistry 290 (28), 17415-17438, 2015 | 133 | 2015 |
| Effect of AZD0530 on cerebral metabolic decline in Alzheimer disease: a randomized clinical trial CH Van Dyck, HB Nygaard, K Chen, MC Donohue, R Raman, ... JAMA neurology 76 (10), 1219-1229, 2019 | 121 | 2019 |
| Cellular prion protein mediates the toxicity of β-amyloid oligomers: implications for Alzheimer disease HB Nygaard, SM Strittmatter Archives of neurology 66 (11), 1325-1328, 2009 | 94 | 2009 |
| Brivaracetam, but not ethosuximide, reverses memory impairments in an Alzheimer’s disease mouse model HB Nygaard, AC Kaufman, T Sekine-Konno, LL Huh, H Going, ... Alzheimer's research & therapy 7, 1-12, 2015 | 88 | 2015 |
| Sleep and EEG power spectral analysis in three transgenic mouse models of Alzheimer’s disease: APP/PS1, 3xTgAD, and Tg2576 BA Kent, SM Strittmatter, HB Nygaard Journal of Alzheimer's Disease 64 (4), 1325-1336, 2018 | 83 | 2018 |
| Current and emerging therapies for Alzheimer’s disease HB Nygaard Clinical therapeutics 35 (10), 1480-1489, 2013 | 53 | 2013 |
| Sleep and its regulation: An emerging pathogenic and treatment frontier in Alzheimer’s disease BA Kent, HH Feldman, HB Nygaard Progress in neurobiology 197, 101902, 2021 | 42 | 2021 |
| Delayed daily activity and reduced NREM slow-wave power in the APPswe/PS1dE9 mouse model of Alzheimer's disease BA Kent, M Michalik, EG Marchant, KW Yau, HH Feldman, RE Mistlberger, ... Neurobiology of Aging 78, 74-86, 2019 | 29 | 2019 |
