Inhibition of RNA polymerase II as a trigger for the p53 response M Ljungman, F Zhang, F Chen, AJ Rainbow, BC McKay Oncogene 18 (3), 583-592, 1999 | 349 | 1999 |
Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53 CT Williamson, E Kubota, JD Hamill, A Klimowicz, R Ye, H Muzik, M Dean, ... EMBO molecular medicine 4 (6), 515-527, 2012 | 146 | 2012 |
Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis BC McKay, M Ljungman, AJ Rainbow Oncogene 17 (5), 545-555, 1998 | 125 | 1998 |
P53 plays a protective role against UV-and cisplatin-induced apoptosis in transcription-coupled repair proficient fibroblasts BC McKay, C Becerril, M Ljungman Oncogene 20 (46), 6805-6808, 2001 | 121 | 2001 |
Regulation of ultraviolet light-induced gene expression by gene size BC McKay, LJ Stubbert, CC Fowler, JM Smith, RA Cardamore, ... Proceedings of the National Academy of Sciences 101 (17), 6582-6586, 2004 | 100 | 2004 |
Focal adhesion kinase inhibitors are potent anti-angiogenic agents MA Cabrita, LM Jones, JL Quizi, LA Sabourin, BC McKay, CL Addison Molecular oncology 5 (6), 517-526, 2011 | 97 | 2011 |
Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene. BC McKay, MA Francis, AJ Rainbow Carcinogenesis 18 (2), 245-249, 1997 | 94 | 1997 |
Potential roles for p53 in nucleotide excision repair BC McKay, M Ljungman, AJ Rainbow Carcinogenesis 20 (8), 1389-1396, 1999 | 88 | 1999 |
UV light-induced degradation of RNA polymerase II is dependent on the Cockayne’s syndrome A and B proteins but not p53 or MLH1 BC McKay, F Chen, ST Clarke, HE Wiggin, LM Harley, M Ljungman Mutation Research/DNA Repair 485 (2), 93-105, 2001 | 80 | 2001 |
The Tumor Suppressor p53 Can Both Stimulate and Inhibit Ultraviolet Light–induced Apoptosis BC McKay, F Chen, CR Perumalswami, F Zhang, M Ljungman Molecular biology of the cell 11 (8), 2543-2551, 2000 | 74 | 2000 |
Role for p53 in the recovery of transcription and protection against apoptosis induced by ultraviolet light BC McKay, M Ljungman Neoplasia 1 (3), 276-284, 1999 | 72 | 1999 |
Compromised genomic integrity impedes muscle growth after Atrx inactivation MS Huh, TP O’Dea, D Ouazia, BC McKay, G Parise, RJ Parks, ... The Journal of clinical investigation 122 (12), 4412-4423, 2012 | 65 | 2012 |
Dose-dependent effects of DNA-damaging agents on p53-mediated cell cycle arrest D Chang, F Chen, F Zhang, BC McKay, M Ljungman | 60 | 1999 |
Preferential estrogen receptor β ligands reduce Bcl-2 expression in hormone-resistant breast cancer cells to increase autophagy SC Ruddy, R Lau, MA Cabrita, C McGregor, BC McKay, LC Murphy, ... Molecular cancer therapeutics 13 (7), 1882-1893, 2014 | 56 | 2014 |
NF-κB-dependent role for cold-inducible RNA binding protein in regulating interleukin 1β C Brochu, MA Cabrita, BD Melanson, JD Hamill, R Lau, MAC Pratt, ... PloS one 8 (2), e57426, 2013 | 56 | 2013 |
Ultraviolet light-induced apoptosis is associated with S-phase in primary human fibroblasts BC McKay, C Becerril, JC Spronck, M Ljungman DNA repair 1 (10), 811-820, 2002 | 55 | 2002 |
Decreased transcription-coupled nucleotide excision repair capacity is associated with increased p53-and MLH1-independent apoptosis in response to cisplatin LJ Stubbert, JM Smith, BC McKay BMC cancer 10, 1-10, 2010 | 48 | 2010 |
The role of mRNA decay in p53-induced gene expression BD Melanson, R Bose, JD Hamill, KA Marcellus, EF Pan, BC McKay Rna 17 (12), 2222-2234, 2011 | 47 | 2011 |
In vitro selections of mammaglobin A and mammaglobin B aptamers for the recognition of circulating breast tumor cells EM Hassan, WG Willmore, BC McKay, MC DeRosa Scientific reports 7 (1), 14487, 2017 | 35 | 2017 |
Lack of functional pRb results in attenuated recovery of mRNA synthesis and increased apoptosis following UV radiation in human breast cancer cells CA Billecke, ME Ljungman, BC McKay, A Rehemtulla, N Taneja, ... Oncogene 21 (29), 4481-4489, 2002 | 35 | 2002 |