Sex and gender: modifiers of health, disease, and medicine F Mauvais-Jarvis, NB Merz, PJ Barnes, RD Brinton, JJ Carrero, ... The Lancet 396 (10250), 565-582, 2020 | 1352 | 2020 |
Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease J Yao, RW Irwin, L Zhao, J Nilsen, RT Hamilton, RD Brinton Proceedings of the National Academy of Sciences 106 (34), 14670-14675, 2009 | 1014 | 2009 |
Progesterone receptors: form and function in brain RD Brinton, RF Thompson, MR Foy, M Baudry, JM Wang, CE Finch, ... Frontiers in neuroendocrinology 29 (2), 313-339, 2008 | 764 | 2008 |
17β-estradiol enhances NMDA receptor-mediated EPSPs and long-term potentiation MR Foy, J Xu, X Xie, RD Brinton, RF Thompson, TW Berger Journal of neurophysiology 81 (2), 925-929, 1999 | 631 | 1999 |
Age, APOE and sex: triad of risk of Alzheimer’s disease BC Riedel, PM Thompson, RD Brinton The Journal of steroid biochemistry and molecular biology 160, 134-147, 2016 | 602 | 2016 |
Steroid modulation of the chloride ionophore in rat brain: structure-activity requirements, regional dependence and mechanism of action. KW Gee, MB Bolger, RE Brinton, H Coirini, BS McEWEN Journal of Pharmacology and Experimental Therapeutics 246 (2), 803-812, 1988 | 562 | 1988 |
Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing SC Cunnane, E Trushina, C Morland, A Prigione, G Casadesus, ... Nature reviews Drug discovery 19 (9), 609-633, 2020 | 561 | 2020 |
Estrogen: a master regulator of bioenergetic systems in the brain and body JR Rettberg, J Yao, RD Brinton Frontiers in neuroendocrinology 35 (1), 8-30, 2014 | 512 | 2014 |
Estrogen, menopause, and the aging brain: how basic neuroscience can inform hormone therapy in women JH Morrison, RD Brinton, PJ Schmidt, AC Gore Journal of Neuroscience 26 (41), 10332-10348, 2006 | 440 | 2006 |
Perimenopause as a neurological transition state RD Brinton, J Yao, F Yin, WJ Mack, E Cadenas Nature reviews endocrinology 11 (7), 393-405, 2015 | 416 | 2015 |
Impact of progestins on estrogen-induced neuroprotection: synergy by progesterone and 19-norprogesterone and antagonism by medroxyprogesterone acetate J Nilsen, RD Brinton Endocrinology 143 (1), 205-212, 2002 | 409 | 2002 |
The healthy cell bias of estrogen action: mitochondrial bioenergetics and neurological implications RD Brinton Trends in neurosciences 31 (10), 529-537, 2008 | 376 | 2008 |
Mechanism of estrogen-mediated neuroprotection: regulation of mitochondrial calcium and Bcl-2 expression J Nilsen, RD Brinton Proceedings of the National Academy of Sciences 100 (5), 2842-2847, 2003 | 345 | 2003 |
Progesterone and estrogen regulate oxidative metabolism in brain mitochondria RW Irwin, J Yao, RT Hamilton, E Cadenas, RD Brinton, J Nilsen Endocrinology 149 (6), 3167-3175, 2008 | 321 | 2008 |
17β-estradiol induced Ca2+ influx via L-type calcium channels activates the Src/ERK/cyclic-AMP response element binding protein signal pathway and BCL-2 expression in rat … TW Wu, JM Wang, S Chen, RD Brinton Neuroscience 135 (1), 59-72, 2005 | 314 | 2005 |
The neurosteroid allopregnanolone promotes proliferation of rodent and human neural progenitor cells and regulates cell-cycle gene and protein expression JM Wang, PB Johnston, BG Ball, RD Brinton Journal of Neuroscience 25 (19), 4706-4718, 2005 | 307 | 2005 |
Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease JM Wang, C Singh, L Liu, RW Irwin, S Chen, EJ Chung, RF Thompson, ... Proceedings of the National Academy of Sciences 107 (14), 6498-6503, 2010 | 305 | 2010 |
Estrogen-induced plasticity from cells to circuits: predictions for cognitive function RD Brinton Trends in pharmacological sciences 30 (4), 212-222, 2009 | 298 | 2009 |
Estrogen receptor subtypes alpha and beta contribute to neuroprotection and increased Bcl-2 expression in primary hippocampal neurons L Zhao, T Wu, RD Brinton Brain research 1010 (1-2), 22-34, 2004 | 295 | 2004 |
Divergent impact of progesterone and medroxyprogesterone acetate (Provera) on nuclear mitogen-activated protein kinase signaling J Nilsen, RD Brinton Proceedings of the National Academy of Sciences 100 (18), 10506-10511, 2003 | 286 | 2003 |