| Mutations within the S4–S5 linker alter voltage sensor constraints in hERG K+ channels AC Van Slyke, S Rezazadeh, M Snopkowski, P Shi, CR Allard, ... Biophysical journal 99 (9), 2841-2852, 2010 | 67 | 2010 |
| A non-covalent ligand reveals biased agonism of the TRPA1 ion channel C Liu, R Reese, S Vu, L Rougé, SD Shields, S Kakiuchi-Kiyota, H Chen, ... Neuron 109 (2), 273-284. e4, 2021 | 64 | 2021 |
| Modulation of hERG K+ Channel Deactivation by Voltage Sensor Relaxation YP Shi, S Thouta, TW Claydon Frontiers in pharmacology 11, 139, 2020 | 24 | 2020 |
| Proton block of the pore underlies the inhibition of hERG cardiac K+ channels during acidosis AC Van Slyke, YM Cheng, P Mafi, CR Allard, CM Hull, YP Shi, ... American Journal of Physiology-Cell Physiology 302 (12), C1797-C1806, 2012 | 24 | 2012 |
| Extracellular protons accelerate hERG channel deactivation by destabilizing voltage sensor relaxation YP Shi, S Thouta, YM Cheng, TW Claydon Journal of General Physiology 151 (2), 231-246, 2019 | 23 | 2019 |
| The hERG channel activator, RPR260243, enhances protective IKr current early in the refractory period reducing arrhythmogenicity in zebrafish hearts YP Shi, ZK Pang, R Venkateshappa, M Gunawan, J Kemp, E Truong, ... American Journal of Physiology-Heart and Circulatory Physiology 319 (2 …, 2020 | 21 | 2020 |
| External protons destabilize the activated voltage sensor in hERG channels YP Shi, YM Cheng, AC Van Slyke, TW Claydon European Biophysics Journal 43, 59-69, 2014 | 17 | 2014 |
| Stabilization of the activated hERG channel voltage sensor by depolarization involves the S4-S5 linker S Thouta, CM Hull, YP Shi, V Sergeev, J Young, YM Cheng, TW Claydon Biophysical Journal 112 (2), 300-312, 2017 | 16 | 2017 |
| Bim regulates alloimmune-mediated vascular injury through effects on T-cell activation and death A von Rossum, W Enns, YP Shi, GE MacEwan, M Malekesmaeli, ... Arteriosclerosis, thrombosis, and vascular biology 34 (6), 1290-1297, 2014 | 11 | 2014 |
| The mechanism of action of external protons on hERG potassium channels Y Shi Simon Fraser University, 2018 | | 2018 |
| External Protons Accelerate Deactivation of hERG Channels by Destabilizing the Relaxed State of the Voltage-Sensor Y Shi, S Thouta, T Claydon Biophysical Journal 114 (3), 293a, 2018 | | 2018 |
| Acidosis Prolongs APD in Optically Mapped Adult Zebrafish Whole Hearts as a Result of hERG Channel Block YP Shi, C Chang, M Gunawan, E Lin, S Shafaattalab, G Tibbits, T Claydon Biophysical Journal 114 (3), 490a, 2018 | | 2018 |
| External Protons Destabilize the Relaxed State of the hERG Channel Voltage Sensor YP Shi, S Thouta, YM Cheng, TW Claydon Biophysical Journal 108 (2), 121a, 2015 | | 2015 |
| Time-Dependent Voltage Sensor Relaxation in hERG Channels S Thouta, YP Shi, S Sokolov, YM Cheng, TW Claydon Biophysical Journal 108 (2), 120a, 2015 | | 2015 |
| Proton block of the pore underlies the inhibition of hERG cardiac K+ channels 1 during acidosis 2 M Hull, YP Shi, TW Claydon | | 2012 |
