Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger PJ Schultheis, LL Clarke, P Meneton, ML Miller, M Soleimani, ... Nature genetics 19 (3), 282-285, 1998 | 913 | 1998 |
Phenotype resembling Gitelman's syndrome in mice lacking the apical Na+-Cl− cotransporter of the distal convoluted tubule PJ Schultheis, JN Lorenz, P Meneton, ML Nieman, TM Riddle, M Flagella, ... Journal of Biological Chemistry 273 (44), 29150-29155, 1998 | 318 | 1998 |
Mouse down-regulated in adenoma (DRA) is an intestinal Cl−/HCO3− exchanger and is up-regulated in colon of mice lacking the NHE3 Na+/H+ exchanger JE Melvin, K Park, L Richardson, PJ Schultheis, GE Shull Journal of Biological Chemistry 274 (32), 22855-22861, 1999 | 306 | 1999 |
Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion. PJ Schultheis, LL Clarke, P Meneton, M Harline, GP Boivin, ... The Journal of clinical investigation 101 (6), 1243-1253, 1998 | 291 | 1998 |
Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures SM Bell, CM Schreiner, PJ Schultheis, ML Miller, RL Evans, CV Vorhees, ... American Journal of Physiology-Cell Physiology 276 (4), C788-C795, 1999 | 288 | 1999 |
Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice T Wang, CL Yang, T Abbiati, PJ Schultheis, GE Shull, G Giebisch, ... American Journal of Physiology-Renal Physiology 277 (2), F298-F302, 1999 | 224 | 1999 |
Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE5) from human brain NR Baird, J Orlowski, EZ Szabó, HC Zaun, PJ Schultheis, AG Menon, ... Journal of Biological Chemistry 274 (7), 4377-4382, 1999 | 200 | 1999 |
Micropuncture analysis of single-nephron function in NHE3-deficient mice JN Lorenz, PJ Schultheis, T Traynor, GE Shull, J Schnermann American Journal of Physiology-Renal Physiology 277 (3), F447-F453, 1999 | 190 | 1999 |
Intestinal NaCl transport in NHE2 and NHE3 knockout mice LR Gawenis, X Stien, GE Shull, PJ Schultheis, AL Woo, NM Walker, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 282 (5 …, 2002 | 176 | 2002 |
Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits PJ Schultheis, SM Fleming, AK Clippinger, J Lewis, T Tsunemi, B Giasson, ... Human molecular genetics 22 (10), 2067-2082, 2013 | 158 | 2013 |
Increased sensitivity to K+ deprivation in colonic H, K-ATPase-deficient mice. P Meneton, PJ Schultheis, J Greeb, ML Nieman, LH Liu, LL Clarke, ... The Journal of clinical investigation 101 (3), 536-542, 1998 | 157 | 1998 |
Characterization of the P5 subfamily of P-type transport ATPases in mice PJ Schultheis, TT Hagen, KK O’Toole, A Tachibana, CR Burke, DL McGill, ... Biochemical and biophysical research communications 323 (3), 731-738, 2004 | 142 | 2004 |
Novel amiloride-sensitive sodium-dependent proton secretion in the mouse proximal convoluted tubule JY Choi, M Shah, MG Lee, PJ Schultheis, GE Shull, S Muallem, M Baum The Journal of clinical investigation 105 (8), 1141-1146, 2000 | 129 | 2000 |
Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2 C Ledoussal, JN Lorenz, ML Nieman, M Soleimani, PJ Schultheis, ... American Journal of Physiology-Renal Physiology 281 (4), F718-F727, 2001 | 125 | 2001 |
Profiling of renal tubule Na+ transporter abundances in NHE3 and NCC null mice using targeted proteomics HL Brooks, AM Sorensen, J Terris, PJ Schultheis, JN Lorenz, GE Shull, ... The Journal of physiology 530 (3), 359-366, 2001 | 118 | 2001 |
Structure-function studies of the Na, K-ATPase. JB Lingrel, J Van Huysse, W O'Brien, E Jewell-Motz, R Askew, ... Kidney International Supplement, 1994 | 117 | 1994 |
Three N-terminal Variants of the AE2 Cl-/HCO3-Exchanger Are Encoded by mRNAs Transcribed from Alternative Promoters (∗) Z Wang, PJ Schultheis, GE Shull Journal of Biological Chemistry 271 (13), 7835-7843, 1996 | 107 | 1996 |
Kinetic analysis of ouabain binding to native and mutated forms of Na, K-ATPase and identification of a new region involved in cardiac glycoside interactions. PJ Schultheis, ET Wallick, JB Lingrel Journal of Biological Chemistry 268 (30), 22686-22694, 1993 | 100 | 1993 |
The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation O Bachmann, B Riederer, H Rossmann, S Groos, PJ Schultheis, GE Shull, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 287 (1 …, 2004 | 97 | 2004 |
Defective fluid secretion and NaCl absorption in the parotid glands of Na+/H+ exchanger-deficient mice K Park, RL Evans, GE Watson, K Nehrke, L Richardson, SM Bell, ... Journal of Biological Chemistry 276 (29), 27042-27050, 2001 | 85 | 2001 |